Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Jeppe Praetorius"'
Autor:
Samuel Loft Sandegaard, Andreas Riishede, Henrik Birn, Helle Hasager Damkier, Jeppe Praetorius
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1904 (2024)
The main characteristic of polycystic kidney disease is the development of multiple fluid-filled renal cysts. The discovery of mislocalized sodium-potassium pump (Na,K-ATPase) in the apical membrane of cyst-lining epithelia alluded to reversal of pol
Externí odkaz:
https://doaj.org/article/7ec21ecc04ab4a2d9b2f42ca707d7a70
Autor:
Inga Baasch Christensen, Qi Wu, Anders Solitander Bohlbro, Marianne Gerberg Skals, Helle Hasager Damkier, Christian Andreas Hübner, Robert Andrew Fenton, Jeppe Praetorius
Publikováno v:
Fluids and Barriers of the CNS, Vol 17, Iss 1, Pp 1-18 (2020)
Abstract Background Genetic disruption of slc4a10, which encodes the sodium-dependent chloride/bicarbonate exchanger Ncbe, leads to a major decrease in Na+-dependent HCO3 − import into choroid plexus epithelial cells in mice and to a marked reducti
Externí odkaz:
https://doaj.org/article/213dd2f37efb4a4ca06b72a4112f550a
Autor:
Dagne Barbuskaite, Fredrik D. Pedersen, Henriette L. Christensen, Laura Ø. Johnsen, Jeppe Praetorius, Helle H. Damkier
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Arterial hypertension, is a common disorder with multiple and variable etiologies. Single nucleotide polymorphism analyses have detected an association between variants in the gene encoding the electrogenic Na+:HCO3– cotransporter NBCe2 (Slc4a5), a
Externí odkaz:
https://doaj.org/article/cb9776fe38d84f568c82fcaa96b9432a
Autor:
Inga Baasch Christensen, Lei Cheng, Jonathan R. Brewer, Udo Bartsch, Robert A. Fenton, Helle H. Damkier, Jeppe Praetorius
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 1569 (2021)
(1) Background: The unusual accumulation of Na,K-ATPase complexes in the brush border membrane of choroid plexus epithelial cells have intrigued researchers for decades. However, the full range of the expressed Na,K-ATPase subunits and their relation
Externí odkaz:
https://doaj.org/article/f9c443bfa6a44a929c511572fb2eb520
Autor:
Thomas Buus Jensen, Muhammad Umar Cheema, Agata Szymiczek, Helle Hasager Damkier, Jeppe Praetorius
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124902 (2015)
Albumin has been identified in preparations of renal distal tubules and collecting ducts by mass spectrometry. This study aimed to establish whether albumin was a contaminant in those studies or actually present in the tubular cells, and if so, ident
Externí odkaz:
https://doaj.org/article/0906eabc185747f0a22d2d512d0712a9
Autor:
Muhammad Umar Cheema, Helle Hasager Damkier, Jakob Nielsen, Ebbe Toftgaard Poulsen, Jan J Enghild, Robert A Fenton, Jeppe Praetorius
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101258 (2014)
Prolonged elevations of plasma aldosterone levels are associated with renal pathogenesis. We hypothesized that renal distress could be imposed by an augmented aldosterone-induced protein turnover challenging cellular protein degradation systems of th
Externí odkaz:
https://doaj.org/article/7f17beb439ba4539ad8bbba623f49866
Autor:
Laura Ø. Johnsen, Kathrine A. Friis, Laura B. Ryø, Jacob G. Mikkelsen, Thomas B. Lindhardt, Rasmus W. Knopper, Brian Hansen, Jeppe Praetorius, Helle H. Damkier
Publikováno v:
Johnsen, L, Friis, K A, Ryø, L B, Mikkelsen, J G, Lindhardt, T B, Knopper, R W, Hansen, B, Praetorius, J & Damkier, H H 2022, ' Regulation of Ncbe in the Choroid Plexus of Mice after Hemorrhage-Induced Hydrocephalus ', The FASEB Journal, vol. 36, no. S1 . https://doi.org/10.1096/fasebj.2022.36.S1.R3405
The choroid plexus (CP) is a small tissue located inside brain ventricles. It is responsible for the production of most of the cerebrospinal fluid (CSF); approximately 500 mL of CSF per day in the adult human [1, 2]. CSF production occurs as a net re
Publikováno v:
The FASEB Journal. 36
Autor:
Sonia Cantel, Pablo Nicolás de Francesco, Maia Uriarte, Gimena Fernandez, Vincent Prevot, Daniel Castrogiovanni, Séverine Denoyelle, Jean-Alain Fehrentz, Mario Perello, Micaela D'Arcangelo, Jeppe Praetorius, Monica Imbernon
Publikováno v:
Uriarte, M, De Francesco, P N, Fernández, G, Castrogiovanni, D, D'Arcangelo, M, Imbernon, M, Cantel, S, Denoyelle, S, Fehrentz, J A, Praetorius, J, Prevot, V & Perello, M 2021, ' Circulating ghrelin crosses the blood-cerebrospinal fluid barrier via growth hormone secretagogue receptor dependent and independent mechanisms ', Molecular and Cellular Endocrinology, vol. 538, 111449 . https://doi.org/10.1016/j.mce.2021.111449
Ghrelin is a peptide hormone mainly secreted from gastrointestinal tract that acts via the growth hormone secretagogue receptor (GHSR), which is highly expressed in the brain. Strikingly, the accessibility of ghrelin to the brain seems to be limited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9dcff22ede8f2ce0701db6a9b9a8bb5
https://pure.au.dk/portal/da/publications/circulating-ghrelin-crosses-the-bloodcerebrospinal-fluid-barrier-via-growth-hormone-secretagogue-receptor-dependent-and-independent-mechanisms(868ca3fa-1d36-4c76-b81d-173cf3d7698c).html
https://pure.au.dk/portal/da/publications/circulating-ghrelin-crosses-the-bloodcerebrospinal-fluid-barrier-via-growth-hormone-secretagogue-receptor-dependent-and-independent-mechanisms(868ca3fa-1d36-4c76-b81d-173cf3d7698c).html
Autor:
Alena Maul, Jeppe Praetorius, Tanja Herrmann, Hannes Maier, Antje K. Huebner, Sandor Nietzsche, Christian A. Hübner
Publikováno v:
J Assoc Res Otolaryngol
Huebner, A K, Maier, H, Maul, A, Nietzsche, S, Herrmann, T, Praetorius, J & Hübner, C A 2019, ' Early Hearing Loss upon Disruption of Slc4a10 in C57BL/6 Mice ', Journal of the Association for Research in Otolaryngology, vol. 20, no. 3, pp. 233-245 . https://doi.org/10.1007/s10162-019-00719-1
Huebner, A K, Maier, H, Maul, A, Nietzsche, S, Herrmann, T, Praetorius, J & Hübner, C A 2019, ' Early Hearing Loss upon Disruption of Slc4a10 in C57BL/6 Mice ', Journal of the Association for Research in Otolaryngology, vol. 20, no. 3, pp. 233-245 . https://doi.org/10.1007/s10162-019-00719-1
The unique composition of the endolymph with a high extracellular K + concentration is essential for sensory transduction in the inner ear. It is secreted by a specialized epithelium, the stria vascularis, that is connected to the fibrocyte meshwork