Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jeppe L. Schaldemose"'
Autor:
Rola Ismail, Peter Parbo, Lasse Stensvig Madsen, Allan K. Hansen, Kim V. Hansen, Jeppe L. Schaldemose, Pernille L. Kjeldsen, Morten G. Stokholm, Hanne Gottrup, Simon F. Eskildsen, David J. Brooks
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-11 (2020)
Abstract Background The aim of this longitudinal study was to assess with positron emission tomography (PET) the relationship between levels of inflammation and the loads of aggregated β-amyloid and tau at baseline and again after 2 years in prodrom
Externí odkaz:
https://doaj.org/article/d6cbb349346a47e69fbe4d108ae94551
Autor:
Martin B. Kinnerup, Michael Sommerauer, Malene F. Damholdt, Jeppe L. Schaldemose, Rola Ismail, Astrid J. Terkelsen, Kristian Stær, Allan Hansen, Tatyana D. Fedorova, Karoline Knudsen, Casper Skjærbæk, Per Borghammer, Nicola Pavese, David J. Brooks, Adjmal Nahimi
Publikováno v:
Neurobiology of Disease, Vol 152, Iss , Pp 105295- (2021)
Noradrenergic neurotransmission may play an important role in tremor modulation through its innervation of key structures of the central tremor circuits. Here, Parkinson's disease (PD) patients with (PDT+) or without (PDT-) rest tremor had 11C-methyl
Externí odkaz:
https://doaj.org/article/09bcadcf9989431db5ce5a4ce09a2016
Autor:
Rasha Hyder, Mads Jensen, Andreas Højlund, Lilli Kimppa, Christopher J. Bailey, Jeppe L. Schaldemose, Martin B. Kinnerup, Karen Østergaard, Yury Shtyrov
Publikováno v:
NeuroImage: Clinical, Vol 32, Iss , Pp 102718- (2021)
Parkinson’s disease (PD) is a neurodegenerative disorder, well-known for its motor symptoms; however, it also adversely affects cognitive functions, including language, a highly important human ability. PD pathology is associated, even in the early
Externí odkaz:
https://doaj.org/article/6d8b58e72f1e41298e2b337019131b4d
Autor:
Peter Parbo, Rola Ismail, Michael Sommerauer, Morten G. Stokholm, Allan K. Hansen, Kim V. Hansen, Ali Amidi, Jeppe L. Schaldemose, Hanne Gottrup, Hans Brændgaard, Simon F. Eskildsen, Per Borghammer, Rainer Hinz, Joel Aanerud, David J. Brooks
Publikováno v:
Neurobiology of Disease, Vol 117, Iss , Pp 211-216 (2018)
Objective: Our aim was to assess with positron emission tomography (PET) the temporal and spatial inter-relationships between levels of cortical microglial activation and the aggregated amyloid-β and tau load in mild cognitive impairment (MCI) and e
Externí odkaz:
https://doaj.org/article/5538e535c0454476a035cf05a4b9006c
Autor:
Karen Østergaard, Jeppe L. Schaldemose, Yury Shtyrov, Rasha Hyder, Andreas Højlund, Christopher J. Bailey, Martin B. Kinnerup, Lilli Kimppa, Mads Jensen
Publikováno v:
NeuroImage: Clinical, Vol 32, Iss, Pp 102718-(2021)
Hyder, R, Jensen, M, Højlund, A, Kimppa, L, Bailey, C J, Schaldemose, J L, Kinnerup, M B, Østergaard, K & Shtyrov, Y 2021, ' Functional connectivity of spoken language processing in early-stage Parkinson's disease: An MEG study ', NeuroImage: Clinical, vol. 32, 102718 . https://doi.org/10.1016/j.nicl.2021.102718
Hyder, R, Jensen, M, Højlund, A, Kimppa, L, Bailey, C J, Schaldemose, J L, Kinnerup, M B, Østergaard, K & Shtyrov, Y 2021, ' Functional connectivity of spoken language processing in early-stage Parkinson's disease: An MEG study ', NeuroImage: Clinical, vol. 32, 102718 . https://doi.org/10.1016/j.nicl.2021.102718
Parkinson’s disease (PD) is a neurodegenerative disorder, well-known for its motor symptoms; however, it also adversely affects cognitive functions, including language, a highly important human ability. PD pathology is associated, even in the early
Autor:
Tatyana D. Fedorova, Christopher E J Doppler, Allan K Hansen, Corinna Brune, Gereon R. Fink, Per Borghammer, David J. Brooks, Martin B. Kinnerup, Michael Sommerauer, Karoline Knudsen, Rola Ismail, Matthew J. Betts, Kristian Stær, Adjmal Nahimi, Aline D. Seger, Jeppe L. Schaldemose, Ezequiel Farrher
Publikováno v:
Brain 144(9), 2732-2744 (2021). doi:10.1093/brain/awab236
Brain 144(9), 2732–2744 (2021). doi:10.1093/brain/awab236
Doppler, C E J, Kinnerup, M B, Brune, C, Farrher, E, Betts, M, Fedorova, T D, Schaldemose, J L, Knudsen, K, Ismail, R, Seger, A D, Hansen, A K, Stær, K, Fink, G R, Brooks, D J, Nahimi, A, Borghammer, P & Sommerauer, M 2021, ' Regional locus coeruleus degeneration is uncoupled from noradrenergic terminal loss in Parkinson's disease ', Brain : a journal of neurology, vol. 144, no. 9, pp. 2732–2744 . https://doi.org/10.1093/brain/awab236
Brain
Brain 144(9), 2732–2744 (2021). doi:10.1093/brain/awab236
Doppler, C E J, Kinnerup, M B, Brune, C, Farrher, E, Betts, M, Fedorova, T D, Schaldemose, J L, Knudsen, K, Ismail, R, Seger, A D, Hansen, A K, Stær, K, Fink, G R, Brooks, D J, Nahimi, A, Borghammer, P & Sommerauer, M 2021, ' Regional locus coeruleus degeneration is uncoupled from noradrenergic terminal loss in Parkinson's disease ', Brain : a journal of neurology, vol. 144, no. 9, pp. 2732–2744 . https://doi.org/10.1093/brain/awab236
Brain
Previous studies have reported substantial involvement of the noradrenergic system in Parkinson’s disease. Neuromelanin-sensitive MRI sequences and PET tracers have become available to visualize the cell bodies in the locus coeruleus and the densit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b6960feec5575c27399353d2becfef
https://pub.dzne.de/record/163310
https://pub.dzne.de/record/163310
Autor:
Michael Sommerauer, Karoline Knudsen, David J. Brooks, Allan K Hansen, Kristian Stær, Adjmal Nahimi, Tatyana D. Fedorova, Jeppe L. Schaldemose, Martin B. Kinnerup, Per Borghammer, Astrid Juhl Terkelsen, Malene Flensborg Damholdt, Rola Ismail, Nicola Pavese, Casper Skjærbæk
Publikováno v:
Kinnerup, M B, Sommerauer, M, Damholdt, M F, Schaldemose, J L, Ismail, R, Terkelsen, A J, Stær, K, Hansen, A, Fedorova, T D, Knudsen, K, Skjærbæk, C, Borghammer, P, Pavese, N, Brooks, D J & Nahimi, A 2021, ' Preserved noradrenergic function in Parkinson's disease patients with rest tremor ', Neurobiology of Disease, vol. 152, 105295 . https://doi.org/10.1016/j.nbd.2021.105295
Neurobiology of Disease, Vol 152, Iss, Pp 105295-(2021)
Neurobiology of Disease, Vol 152, Iss, Pp 105295-(2021)
Noradrenergic neurotransmission may play an important role in tremor modulation through its innervation of key structures of the central tremor circuits. Here, Parkinson's disease (PD) patients with (PDT+) or without (PDT-) rest tremor had 11C-methyl
Autor:
Morten Gersel Stokholm, Rola Ismail, Simon Fristed Eskildsen, Hanne Gottrup, Allan K Hansen, Kim V. Hansen, David J. Brooks, Peter Parbo, Pernille L. Kjeldsen, Lasse Stensvig Madsen, Jeppe L. Schaldemose
Publikováno v:
Ismail, R, Parbo, P, Madsen, L S, Hansen, A K, Hansen, K V, Schaldemose, J L, Kjeldsen, P L, Stokholm, M G, Gottrup, H, Eskildsen, S F & Brooks, D J 2020, ' The relationships between neuroinflammation, beta-amyloid and tau deposition in Alzheimer's disease : a longitudinal PET study ', Journal of Neuroinflammation, vol. 17, no. 1, 151 . https://doi.org/10.1186/s12974-020-01820-6
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-11 (2020)
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-11 (2020)
Journal of Neuroinflammation
Background The aim of this longitudinal study was to assess with positron emission tomography (PET) the relationship between levels of inflammation and the loads of aggregated β-amyloid and tau at baseline and again after 2 years in prodromal Alzhei
Autor:
Jeppe L. Schaldemose, Rikke Beese Dalby, Sanne Hage la Cour, Rola Ismail, K. Hansen, Simon Fristed Eskildsen, Per Qvist, Anna Tietze, David J. Brooks, Hanne Gottrup, Pernille L. Kjeldsen, Peter Parbo
Publikováno v:
Ismail, R, Parbo, P, Hansen, K V, Schaldemose, J L, Dalby, R B, Tietze, A, Kjeldsen, P L, la Cour, S H, Qvist, P, Gottrup, H, Eskildsen, S F & Brooks, D J 2019, ' Abnormal Amyloid Load in Mild Cognitive Impairment : The Effect of Reducing the PiB-PET Threshold ', Journal of Neuroimaging . https://doi.org/10.1111/jon.12629
Ismail, R, Parbo, P, Hansen, K V, Schaldemose, J L, Dalby, R B, Tietze, A, Kjeldsen, P L, la Cour, S H, Qvist, P, Gottrup, H, Eskildsen, S F & Brooks, D J 2019, ' Abnormal Amyloid Load in Mild Cognitive Impairment : The Effect of Reducing the PiB-PET Threshold ', Journal of Neuroimaging, vol. 29, no. 4, pp. 499-505 . https://doi.org/10.1111/jon.12629
Ismail, R, Parbo, P, Hansen, K V, Schaldemose, J L, Dalby, R B, Tietze, A, Kjeldsen, P L, la Cour, S H, Qvist, P, Gottrup, H, Eskildsen, S F & Brooks, D J 2019, ' Abnormal Amyloid Load in Mild Cognitive Impairment : The Effect of Reducing the PiB-PET Threshold ', Journal of Neuroimaging, vol. 29, no. 4, pp. 499-505 . https://doi.org/10.1111/jon.12629
BACKGROUND AND PURPOSE: In vivo detection of β-amyloid (Aβ) plaques in Alzheimer's disease (AD) is now possible with 11C-PiB positron emission tomography (PET). Conventionally, a cortical:cerebellar PiB uptake ratio threshold of 1.4-1.5 has been us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da3d12b3999f8e8f29140a4a5a560451
https://pure.au.dk/ws/files/162833291/Rola_PiB_Threshold.pdf
https://pure.au.dk/ws/files/162833291/Rola_PiB_Threshold.pdf
Autor:
Ali Amidi, Rainer Hinz, Allan K Hansen, Hanne Gottrup, Hans Brændgaard, Kim V. Hansen, Simon Fristed Eskildsen, David J. Brooks, Per Borghammer, Michael Sommerauer, Jeppe L. Schaldemose, Morten Gersel Stokholm, Joel Aanerud, Peter Parbo, Rola Ismail
Publikováno v:
Parbo, P, Ismail, R, Sommerauer, M, Stokholm, M G, Hansen, A K, Hansen, K V, Amidi, A, Schaldemose, J L, Gottrup, H, Braendgaard, H, Eskildsen, S F, Borghammer, P, Hinz, R, Aanerud, J & Brooks, D J 2018, ' Does inflammation precede tau aggregation in early Alzheimer's disease? A PET study ', Neurobiology of disease, vol. 117 . https://doi.org/10.1016/j.nbd.2018.06.004
Parbo, P, Ismail, R, Sommerauer, M, Stokholm, M G, Hansen, A K, Hansen, K V, Amidi, A, Schaldemose, J L, Gottrup, H, Brændgaard, H, Eskildsen, S F, Borghammer, P, Hinz, R, Aanerud, J & Brooks, D J 2018, ' Does inflammation precede tau aggregation in early Alzheimer's disease? A PET study ', Neurobiology of Disease, vol. 117, pp. 211-216 . https://doi.org/10.1016/j.nbd.2018.06.004
Neurobiology of Disease, Vol 117, Iss, Pp 211-216 (2018)
Parbo, P, Ismail, R, Sommerauer, M, Stokholm, M G, Hansen, A K, Hansen, K V, Amidi, A, Schaldemose, J L, Gottrup, H, Brændgaard, H, Eskildsen, S F, Borghammer, P, Hinz, R, Aanerud, J & Brooks, D J 2018, ' Does inflammation precede tau aggregation in early Alzheimer's disease? A PET study ', Neurobiology of Disease, vol. 117, pp. 211-216 . https://doi.org/10.1016/j.nbd.2018.06.004
Neurobiology of Disease, Vol 117, Iss, Pp 211-216 (2018)
Objective: Our aim was to assess with positron emission tomography (PET) the temporal and spatial inter-relationships between levels of cortical microglial activation and the aggregated amyloid-β and tau load in mild cognitive impairment (MCI) and e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c3c2dc4bec81bd1b83b0929b34f61d7
https://pure.manchester.ac.uk/ws/files/71602001/NBD_18_181R1.pdf
https://pure.manchester.ac.uk/ws/files/71602001/NBD_18_181R1.pdf