Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Jeongsil Kim-Ha"'
Autor:
Si-Cho Kim, Da-Won Kim, Eun Ju Cho, Jin-Young Lee, Jiwon Kim, Chaesun Kwon, Jeongsil Kim-Ha, Suk Kyun Hong, YoungRok Choi, Nam-Joon Yi, Kwang-Woong Lee, Kyung-Suk Suh, Won Kim, Woojin Kim, Hyunsoo Kim, Yoon Jun Kim, Jung-Hwan Yoon, Su Jong Yu, Young-Joon Kim
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-6 (2023)
Abstract To address the shortcomings of current hepatocellular carcinoma (HCC) surveillance tests, we set out to find HCC-specific methylation markers and develop a highly sensitive polymerase chain reaction (PCR)-based method to detect them in circu
Externí odkaz:
https://doaj.org/article/04e81ec649cb41649c35ba5e97d55fed
Publikováno v:
BMB Reports. 56:240-245
Autor:
Si-Cho Kim, Jiwon Kim, Da-Won Kim, Yanghee Choi, Kyunghyun Park, Eun Ju Cho, Su Jong Yu, Jeongsil Kim-Ha, Young-Joon Kim
Publikováno v:
BMB Reports. 55:553-558
Autor:
Wook-Bin Lee, Ji-Seon Kang, Won Young Choi, Quanri Zhang, Chul Han Kim, Un Yung Choi, Jeongsil Kim-Ha, Young-Joon Kim
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Resolution of granulomas in mycobacterial infection requires macrophages to switch from cytokine to nitric oxide (NO) production. Here the authors show that Mincle stimulates translation of the key NO synthesis genes by a mechanism dependent on p38-m
Externí odkaz:
https://doaj.org/article/ae17c8e545c24eaeac56e1a53a11d707
Autor:
Li Hua Jin, Jaewon Shim, Joon Sun Yoon, Byungil Kim, Jihyun Kim, Jeongsil Kim-Ha, Young-Joon Kim
Publikováno v:
PLoS Pathogens, Vol 4, Iss 10, p e1000168 (2008)
Essential aspects of the innate immune response to microbial infection appear to be conserved between insects and mammals. Although signaling pathways that activate NF-kappaB during innate immune responses to various microorganisms have been studied
Externí odkaz:
https://doaj.org/article/b97ab7b764a4456093fe8fe4589e78c2
Autor:
Lark Kyun Kim, Un Yung Choi, Hwan Sung Cho, Jung Seon Lee, Wook-bin Lee, Jihyun Kim, Kyoungsuk Jeong, Jaewon Shim, Jeongsil Kim-Ha, Young-Joon Kim
Publikováno v:
PLoS Biology, Vol 5, Iss 9, p e238 (2007)
The activation of several transcription factors is required for the elimination of infectious pathogens via the innate immune response. The transcription factors NF-kappaB, AP-1, and STAT play major roles in the synthesis of immune effector molecules
Externí odkaz:
https://doaj.org/article/a6c87e249fb148fc9632b12232f2879d
Autor:
Young Joon Kim, Jeongsil Kim-Ha
Publikováno v:
BMB Reports
Accumulating evidence indicates many brain functions are mediated by epigenetic regulation of neural genes, and their dysregulations result in neuronal disorders. Experiences such as learning and recall, as well as physical exercise, induce neuronal
Publikováno v:
BMB Reports
Upon viral infection, the 2', 5'-oligoadenylate synthetase (OAS)-ribonuclease L (RNaseL) system works to cleave viral RNA, thereby blocking viral replication. However, it is unclear whether OAS proteins have a role in regulating gene expression. Here
Autor:
Goo Taeg Oh, Yoonhee Jin, Sun Min Lee, Jungwoo Lee, Seung Woo Cho, Sejin Jeon, Won Young Choi, Kyung-Min Noh, Jeongsil Kim-Ha, Young Joon Kim
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(10)
CpG, 5'-C-phosphate-G-3', islands (CGIs) have long been known for their association with enhancers, silencers, and promoters, and for their epigenetic signatures. They are maintained in embryonic stem cells (ESCs) in a poised but inactive state via t
Autor:
Young Joon Kim, Jungwoo Lee, Dawon Kim, Won Young Choi, Sun Min Lee, Jin-Young Lee, Eunji Choi, Jeongsil Kim-Ha
Publikováno v:
Epigenomics. 8(7)
Genetic and epigenetic alterations play prominent roles in hepatocarcinogenesis and their appearance varies depending on etiological factors, race and tumor progression. Intriguingly, distinct patterns of these genetic and epigenetic mutations are co