Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Jeongheon Yoon"'
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Human regulatory CD4+ T cells (Tregs) are potent immunosuppressive lymphocytes responsible for immune tolerance and homeostasis. Since the seminal reports identifying Tregs, vast research has been channeled into understanding their genesis, signature
Externí odkaz:
https://doaj.org/article/e092af0c87494f64b1857cf02c0c4baa
Autor:
Elena M Pugacheva, Teruhiko Suzuki, Svetlana D Pack, Natsuki Kosaka-Suzuki, Jeongheon Yoon, Alexander A Vostrov, Eugene Barsov, Alexander V Strunnikov, Herbert C Morse, Dmitri Loukinov, Victor Lobanenkov
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e13872 (2010)
BORIS/CTCFL is a paralogue of CTCF, the major epigenetic regulator of vertebrate genomes. BORIS is normally expressed only in germ cells but is aberrantly activated in numerous cancers. While recent studies demonstrated that BORIS is a transcriptiona
Externí odkaz:
https://doaj.org/article/ea03c98b6d9b4c789955d56d6cf365ec
Publikováno v:
PLoS ONE, Vol 3, Iss 5, p e2234 (2008)
Germline-stem cells (GSCs) produce gametes and are thus true "immortal stem cells". In Drosophila ovaries, GSCs divide asymmetrically to produce daughter GSCs and cystoblasts, and the latter differentiate into germline cysts. Here we show that the hi
Externí odkaz:
https://doaj.org/article/665cb664e4e64fc098f27890de9690fb
Autor:
Solomon Conteh, Javier Traba, Chen-Feng Qi, Dong-Mi Shin, Shweta Jain, Patrick E. Duffy, Jeongheon Yoon, Wendy Dubois, Ines Gonzalez-Garcia, Herbert C. Morse, Zohreh Naghashfar, Alexander L. Kovalchuk, Sadia Abbasi, Sungyun Kang, Hongsheng Wang, Michael N. Sack, Jiafang Sun, Yuanyuan Gao
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports
Scientific Reports
Survival of antibody-secreting plasma cells (PCs) is vital for sustained antibody production. However, it remains poorly understood how long-lived PCs (LLPCs) are generated and maintained. Here we report that ectonucleotide pyrophosphatase/phosphodie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc585fc85c35821bd4a2a380590cef9
http://link.springer.com/article/10.1038/s41598-017-18028-z
http://link.springer.com/article/10.1038/s41598-017-18028-z
Publikováno v:
Blood. 129:238-245
Replacement therapy with factor VIII (FVIII) is used in patients with hemophilia A for treatment of bleeding episodes or for prophylaxis. A common and serious problem with this therapy is the patient's immune response to FVIII, because of a lack of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad892a17cf4b46c8980253a402a1fb03
https://doi.org/10.1182/blood-2016-07-727834
https://doi.org/10.1182/blood-2016-07-727834
Publikováno v:
Cell Immunol
Type 1 Diabetes (T1D) is an autoimmune disease marked by direct elimination of insulin-producing β cells by autoreactive T effectors. Recent T1D clinical trials utilizing autologous Tregs transfers to restore immune balance and improve disease has p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4475a9dab0dcb269f6116caf18bd4c2a
https://doi.org/10.1016/j.cellimm.2020.104224
https://doi.org/10.1016/j.cellimm.2020.104224
Autor:
Herbert C. Morse, Yong Chan Kim, Sadia Abbasi, Momoko Yoshimoto, Jeongheon Yoon, Hongsheng Wang
Publikováno v:
Immunology & Cell Biology. 94:719-728
Plasma cell alloantigen 1 (PC1), also known as ENPP1 (ectonucleotide pyrophosphatase/phosphodiesterase 1), is an enzyme involved primarily in hydrolysis of adenosine triphosphate at the cell surface. Although the expression pattern of PC1 is relative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8106db49c9abb80d164edfd7cfba775e
https://doi.org/10.1038/icb.2016.31
https://doi.org/10.1038/icb.2016.31
Publikováno v:
Cellular Immunology. 301:74-81
The immune response of hemophilia A patients to administered FVIII is a major complication that obviates this very therapy. We have recently described the use of synthetic, biodegradable nanoparticles carrying rapamycin and FVIII peptide antigens, to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56350f565a2e8317d4bbdd426d0d2e58
https://doi.org/10.1016/j.cellimm.2015.11.004
https://doi.org/10.1016/j.cellimm.2015.11.004
Clinical application of Ag-specific T regulatory cells (Tregs) offers promise for the treatment of undesirable immune diseases. To achieve this goal, long-term expansion of Tregs is required to obtain sufficient numbers of cells. However, human Tregs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f075f7f3737313c9e8254fbc037f9877
https://europepmc.org/articles/PMC6125212/
https://europepmc.org/articles/PMC6125212/
Autor:
Kai W. Wucherpfennig, Ai-Hong Zhang, Yong Chan Kim, Jeongheon Yoon, William E. Culp, Jason R. Lees, David W. Scott
Publikováno v:
Journal of autoimmunity. 92
Expanded polyclonal T regulatory cells (Tregs) offer great promise for the treatment of immune-mediated diseases. Inhibition by Tregs is under the control of the T-cell receptor (TCR). Therefore, we created Tregs with defined antigen specificity, usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::140e883fced6d6990fb88590ef5c4f8c
https://pubmed.ncbi.nlm.nih.gov/29857928
https://pubmed.ncbi.nlm.nih.gov/29857928