Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Jeongeun Hyun"'
Autor:
So Jung Kim, Jeongeun Hyun
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/43ffdf69511b46d380115716f0a2443c
Autor:
Sung‐Min Park, Jung‐Hwan Lee, Kwang Sung Ahn, Hye Won Shim, Ji‐Young Yoon, Jeongeun Hyun, Jun Hee Lee, Sunyoung Jang, Kyung Hyun Yoo, Yoon‐Kwan Jang, Tae‐Jin Kim, Hyun Kyu Kim, Man Ryul Lee, Jun‐Hyeog Jang, Hosup Shim, Hae‐Won Kim
Publikováno v:
Advanced Science, Vol 10, Iss 32, Pp n/a-n/a (2023)
Abstract Advancing the technologies for cellular reprogramming with high efficiency has significant impact on regenerative therapy, disease modeling, and drug discovery. Biophysical cues can tune the cell fate, yet the precise role of external physic
Externí odkaz:
https://doaj.org/article/e33d70cb762d44bd8b98683ebb4a70ba
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3092 (2024)
Non-alcoholic fatty liver disease (NAFLD) has emerged as a significant liver ailment attributed to factors like obesity and diabetes. While ongoing research explores treatments for NAFLD, further investigation is imperative to address this escalating
Externí odkaz:
https://doaj.org/article/c87973d2e443424497db061f06af3166
Autor:
Cynthia A. Moylan, Alisha M. Mavis, Dereje Jima, Rachel Maguire, Mustafa Bashir, Jeongeun Hyun, Melanie N. Cabezas, Alice Parish, Donna Niedzwiecki, Anna Mae Diehl, Susan K. Murphy, Manal F. Abdelmalek, Cathrine Hoyo
Publikováno v:
Epigenetics, Vol 17, Iss 11, Pp 1446-1461 (2022)
Non-Alcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease in children. Epigenetic alterations, such as through DNA methylation (DNAm), may link adverse childhood exposures and fatty liver and provide non-invasive methods
Externí odkaz:
https://doaj.org/article/340dddde15ac419da0f5f9f960cb993c
Autor:
Kuo Du, Satish K. Chitneni, Ayako Suzuki, Ying Wang, Ricardo Henao, Jeongeun Hyun, Richard T. Premont, Susanna Naggie, Cynthia A. Moylan, Mustafa R. Bashir, Manal F. Abdelmalek, Anna Mae Diehl
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 1, Pp 1-21 (2020)
Background & Aims: Nonalcoholic steatohepatitis (NASH) occurs in the context of aberrant metabolism. Glutaminolysis is required for metabolic reprograming of hepatic stellate cells (HSCs) and liver fibrogenesis in mice. However, it is unclear how cha
Externí odkaz:
https://doaj.org/article/2913df394d7c4f06abb93625a9bfe0c6
Autor:
Sihyung Wang, Youngmi Jung, Jeongeun Hyun, Matthew Friedersdorf, Seh-Hoon Oh, Jieun Kim, Richard T. Premont, Jack D. Keene, Anna Mae Diehl
Publikováno v:
Cellular Physiology and Biochemistry, Vol 48, Iss 3, Pp 1215-1229 (2018)
Background/Aims: Myofibroblasts (MF) derived from quiescent nonfibrogenic hepatic stellate cells (HSC) are the major sources of fibrous matrix in cirrhosis. Because many factors interact to regulate expansion and regression of MF-HSC populations, eff
Externí odkaz:
https://doaj.org/article/79865b208d884ea78ffe5ee0a26e1ad6
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5717 (2021)
Alcoholic liver disease (ALD) is a globally prevalent chronic liver disease caused by chronic or binge consumption of alcohol. The liver is the major organ that metabolizes alcohol; therefore, it is particularly sensitive to alcohol intake. Metabolit
Externí odkaz:
https://doaj.org/article/7464c14a43344b9392315f6da805247f
Publikováno v:
Biomedicines, Vol 9, Iss 4, p 347 (2021)
Liver cancer is one of the most common cancers worldwide, and its prevalence and mortality rate are increasing due to the lack of biomarkers and effective treatments. The Hippo signaling pathway has long been known to control liver size, and genetic
Externí odkaz:
https://doaj.org/article/6ae5f9fbe1b3475794b592b805601f1c
Autor:
Jieun Kim, Jeongeun Hyun, Sihyung Wang, Chanbin Lee, Jae-Wook Lee, Eun-Yi Moon, Heejae Cha, Anna Mae Diehl, Youngmi Jung
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract The molecular mechanisms of thymosin beta-4 (TB4) involved in regulating hepatic stellate cell (HSC) functions remain unclear. Therefore, we hypothesize that TB4 influences HSC activation through hedgehog (Hh) pathway. HSC functions declined
Externí odkaz:
https://doaj.org/article/de1193bb16be4930b317ead645d89755
Publikováno v:
Cellular Physiology and Biochemistry, Vol 40, Iss 1-2, Pp 263-276 (2016)
Background/Aims: Radiation-induced liver disease (RILD) is a major obstacle in treating liver cancer; however, the mechanisms underlying RILD development remain unclear. Hedgehog (Hh) orchestrates liver response to injury. Herein, we investigated the
Externí odkaz:
https://doaj.org/article/831e8a514b2946faa67662f6329b3447