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pro vyhledávání: '"JeongGoo Lee"'
Autor:
JeongGoo Lee, Martin Heur
Publikováno v:
Taiwan Journal of Ophthalmology, Vol 13, Iss 1, Pp 28-33 (2023)
PURPOSE: The inducible Cre-ERT2 recombinase system allows for temporal control of gene targeting, and it is useful to studying adult function of genes that have critical developmental roles. The Zeb1flox/flox: UBC-CreERT2 mouse was generated to condi
Externí odkaz:
https://doaj.org/article/63b6088d4ea74e648b10fc60d869971c
Publikováno v:
Molecular Vision, Vol 25, Iss 1, Pp 22-34 (2019)
Purpose: To determine whether the mouse corneal endothelium enters endothelial to mesenchymal transition (EndoMT) following surgical injury in vivo. Methods: The corneal endothelium in anesthetized mice was surgically injured in vivo under direct
Externí odkaz:
https://doaj.org/article/27ed4f63756b4419b32c74beef102792
Autor:
Martin Heur, JeongGoo Lee
Publikováno v:
Taiwan Journal of Ophthalmology. 13:28
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose ZEB1 is induced during endothelial-mesenchymal transition (EnMT) in the cornea. Induction of SP1 and SP3 by ZEB1 along with identification of putative SP1 and SP3 binding sites in promoters of EnMT-associated gene lead us to investigate their