Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Jeong Su Oh"'
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 2, Pp 319-328 (2024)
Abstract DNA damage is a critical threat that poses significant challenges to all cells. To address this issue, cells have evolved a sophisticated molecular and cellular process known as the DNA damage response (DDR). Among the various cell types, ma
Externí odkaz:
https://doaj.org/article/4da5548b101748c3897732840ca5c6e1
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Background The maintenance of spindle pole integrity is essential for spindle assembly and chromosome segregation during mitosis. However, the underlying mechanisms governing spindle pole integrity remain unclear. Methods ENSA was inhibited
Externí odkaz:
https://doaj.org/article/082b81eb6ac24244bbc199a385ff893b
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Fungicides are a type of pesticide used to protect plants and crops from pathogenic fungi. Azoxystrobin (AZO), a natural methoxyacrylate derived from strobilurin, is one of the most widely used fungicides in agriculture. AZO exerts its fungicidal act
Externí odkaz:
https://doaj.org/article/87a310a53907414287c6029c1cd48909
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Maintaining genome integrity in germ cells is essential not only for successful fertilization and embryo development, but also to ensure proper transmission of genetic information across generations. However, unlike oocytes, sperm are incapable of re
Externí odkaz:
https://doaj.org/article/8216c772d54342deac8ca352c1709b6f
Autor:
Minsung Kang, Navin Pandit, Ah-Young Kim, Suk Joon Cho, Young-Ju Kwon, Jiyeon Ahn, Kyu Myung Lee, Sangwook Wu, Jeong Su Oh, Kwan-Young Jung, Jae-Sung Kim
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
As pyrazole and its derivatives have a wide range of biological activities, including anticancer activity, the design of novel pyrazole derivatives has emerged as an important research field. This study describes a novel pyrazole derivative that exer
Externí odkaz:
https://doaj.org/article/4db7d44355174c20958e4f145bd37aea
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
If fertilization does not occur for a prolonged time after ovulation, oocytes undergo a time-dependent deterioration in quality in vivo and in vitro, referred to as postovulatory aging. The DNA damage response is thought to decline with aging, but li
Externí odkaz:
https://doaj.org/article/2006dd7952554521a0757258be755cc7
Autor:
Hyuk-Joon Jeon, Jeong Su Oh
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
In eukaryotic chromosomes, the centromere and telomere are two specialized structures that are essential for chromosome stability and segregation. Although centromeres and telomeres often are located in close proximity to form telocentric chromosomes
Externí odkaz:
https://doaj.org/article/4678fa6bdd104a0dbfdd649431261215
Publikováno v:
Toxics, Vol 10, Iss 6, p 327 (2022)
The polycyclic aromatic hydrocarbon quinone derivative 9,10-phenanthrenequinone (9,10-PQ) is one of the most abundant and toxic components found in diesel exhaust particles (DEPs). These DEPs are created during diesel fuel combustion and are consider
Externí odkaz:
https://doaj.org/article/5394b96ff86049daa5976469e2c234cc
Autor:
Hyuk-Joon Jeon, Jeong Su Oh
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Dynamic changes in microtubules during cell cycle progression are essential for spindle organization to ensure proper segregation of chromosomes. There is growing evidence that post translational modifications of tubulins are the key factors that con
Externí odkaz:
https://doaj.org/article/8a866d68d1204f6192b35bff5d234f46
Autor:
Ah-Young Kim, Yi Na Yoon, Jiyeon Leem, Jee-Young Lee, Kwan-Young Jung, Minsung Kang, Jiyeon Ahn, Sang-Gu Hwang, Jeong Su Oh, Jae-Sung Kim
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Although MASTL (microtubule-associated serine/threonine kinase-like) is an attractive target for anticancer treatment, MASTL inhibitors with antitumor activity have not yet been reported. In this study, we have presented a novel MASTL inhibitor, MKI-
Externí odkaz:
https://doaj.org/article/deebaccfdb9545038d2e114446e25c67