Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Jeong Seop Rhee"'
Autor:
Nina Rößler, Tassilo Jungenitz, Albrecht Sigler, Alexander Bird, Martin Mittag, Jeong Seop Rhee, Thomas Deller, Hermann Cuntz, Nils Brose, Stephan W. Schwarzacher, Peter Jedlicka
Publikováno v:
Open Biology, Vol 13, Iss 8 (2023)
Dendritic spines are crucial for excitatory synaptic transmission as the size of a spine head correlates with the strength of its synapse. The distribution of spine head sizes follows a lognormal-like distribution with more small spines than large on
Externí odkaz:
https://doaj.org/article/bd78c7109d364e9c9d436be340b75e5d
Autor:
Hong Jun Rhee, Ali H. Shaib, Kristina Rehbach, ChoongKu Lee, Peter Seif, Carolina Thomas, Erinn Gideons, Anja Guenther, Tamara Krutenko, Matthias Hebisch, Michael Peitz, Nils Brose, Oliver Brüstle, Jeong Seop Rhee
Publikováno v:
Cell Reports, Vol 27, Iss 7, Pp 2212-2228.e7 (2019)
Summary: iPSC-derived human neurons are expected to revolutionize studies on brain diseases, but their functional heterogeneity still poses a problem. Key sources of heterogeneity are the different cell culture systems used. We show that an optimized
Externí odkaz:
https://doaj.org/article/be79eb1df6054ca6a5dd84a11de59ece
Autor:
Dennis B. Nestvogel, Ricardo Martins Merino, Carolina Leon-Pinzon, Manuel Schottdorf, ChoongKu Lee, Cordelia Imig, Nils Brose, Jeong-Seop Rhee
Publikováno v:
Cell Reports, Vol 30, Iss 10, Pp 3261-3269.e4 (2020)
Summary: Short-term plasticity gates information transfer across neuronal synapses and is thought to be involved in fundamental brain processes, such as cortical gain control and sensory adaptation. Neurons employ synaptic vesicle priming proteins of
Externí odkaz:
https://doaj.org/article/5e7eccf9d8674c90a53cc788990e52c9
Autor:
Lena S. Mortensen, Silvia J.H. Park, Jiang-bin Ke, Benjamin H. Cooper, Lei Zhang, Cordelia Imig, Siegrid Löwel, Kerstin Reim, Nils Brose, Jonathan B. Demb, Jeong-Seop Rhee, Joshua H. Singer
Publikováno v:
Cell Reports, Vol 15, Iss 10, Pp 2239-2250 (2016)
Complexin (Cplx) proteins modulate the core SNARE complex to regulate exocytosis. To understand the contributions of Cplx to signaling in a well-characterized neural circuit, we investigated how Cplx3, a retina-specific paralog, shapes transmission a
Externí odkaz:
https://doaj.org/article/3c96857817d840289321a4eb85904210
Autor:
Olaf Jahn, Stefan Bonn, Klaus P. Hellmann, Nils Brose, Marilyn Tirard, Kamal Chowdhury, Jeong-Seop Rhee, Orr Shomroni, Silvia Ripamonti
Publikováno v:
Journal of neurochemistry 154(6), 647-661 (2020). doi:10.1111/jnc.15008
SUMOylation is a dynamic post-translational protein modification that primarily takes place in cell nuclei, where it plays a key role in multiple DNA-related processes. In neurons, the SUMOylation-dependent control of a subset of neuronal transcripti
Autor:
Rachel Straussberg, Marta Rosário, Guntram Borck, Victor Tarabykin, Olaf Jahn, Stephen Horan, A Ioana Weber, Rüstem Yilmaz, Ekrem Dere, Alina Smorodchenko, Hong Jun Rhee, Jeong-Seop Rhee, Susanne Mueller, Katrin I. Willig, Philipp Boehm-Sturm, Manuela Schwark, Mateusz C. Ambrozkiewicz, Sami Zaqout, Ekaterina Borisova, Theres Schaub, Bekir Altas, Silvia Ripamonti, Hiroshi Kawabe, Lars Piepkorn
Publikováno v:
Molecular Psychiatry. 26:1980-1995
Kaufman oculocerebrofacial syndrome (KOS) is a severe autosomal recessive disorder characterized by intellectual disability, developmental delays, microcephaly, and characteristic dysmorphisms. Biallelic mutations of UBE3B, encoding for a ubiquitin l
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 20
International Journal of Molecular Sciences, Vol 22, Iss 11268, p 11268 (2021)
Volume 22
Issue 20
International Journal of Molecular Sciences, Vol 22, Iss 11268, p 11268 (2021)
Ca2+ entry through Cav1.3 Ca2+ channels plays essential roles in diverse physiological events. We employed yeast-two-hybrid (Y2H) assays to mine novel proteins interacting with Cav1.3 and found Snapin2, a synaptic protein, as a partner interacting wi
Publikováno v:
International Journal of Molecular Sciences
Ca2+ entry through Cav1.3 Ca2+ channels plays essential roles in diverse physiological events. We employed yeast-two-hybrid (Y2H) assays to mine novel proteins interacting with Cav1.3 and found Snapin2, a synaptic protein, as a partner interacting wi
Autor:
Katharina Kronenberg, Thomas Michaelis, Jeong-Seop Rhee, Katrin I. Willig, Lena Spieth, Torben Ruhwedel, Sina K. Stumpf, Takashi Watanabe, Sabine Hofer, Niels Kruse, Tim Düking, Christine Stadelmann, Gesine Saher, Jan Winchenbach, Stefan A. Berghoff, Susana Minguet, Wiebke Möbius, Christian von der Brelie, Ali H Shaib, Nina Gerndt, Peter Michels, Jens Frahm, Petra Hülper, Uwe Karst
Publikováno v:
Neuro-oncology Advances
Neuro-Oncology Advances
Neuro-Oncology Advances
Background Pharmaceutical intervention in the CNS is hampered by the shielding function of the blood–brain barrier (BBB). To induce clinical anesthesia, general anesthetics such as isoflurane readily penetrate the BBB. Here, we investigated whether
Autor:
Ji Won Um, Chooungku Lee, Jeong-Seop Rhee, Hee-Yoon Lee, Xinran Liu, Jungsu Shin, Se-Young Choi, Kyung Ah Han, Dongseok Lim, Jaewon Ko, Taek Han Yoon
Leukocyte common antigen-related receptor tyrosine phosphatases (LAR-RPTPs) are evolutionarily conserved presynaptic organizers. The synaptic role of vertebrate LAR-RPTPs in vivo, however, remains unclear. This study systematically analyzed the effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f2069fa078830d3461877627afdf57
https://doi.org/10.1101/2020.01.10.901546
https://doi.org/10.1101/2020.01.10.901546