Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jeong Sang Yi"'
Autor:
Junpyo Gong, Jeong Sang Yi, Hang Su Cho, Chang Hun Shin, Hyung-Jin Won, Byung-Kwan Cho, Minsoo Noh, Yeo Joon Yoon
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-7 (2023)
Abstract Streptomyces clavuligerus NRRL 3585 is a native producer of clavulanic acid (CA), a clinically used β-lactamase inhibitor, and is widely used as an industrial strain for the production of antibiotics. Selective random mutagenesis has succes
Externí odkaz:
https://doaj.org/article/bd1a8667b6e84837ad290dffec6236aa
Autor:
Jeong Sang Yi, Jung Min Kim, Min-Kyoung Kang, Jong Hoon Kim, Hang Su Cho, Yeon Hee Ban, Myoung Chong Song, Kwang-Hee Son, Yeo Joon Yoon
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-18 (2022)
Abstract Background Nematodes are parasitic animals that cause over 100 billion US dollars loss in agricultural business. The whole-genomes of two Streptomyces strains, Streptomyces spectabilis KCTC9218T and Streptomyces sp. AN091965, were sequenced.
Externí odkaz:
https://doaj.org/article/02d7e03f6c9741a68105a668a806b2b0
Publikováno v:
Natural Product Reports. 40:972-987
This highlight covers the recent advances in the metabolic engineering and combinatorial biosynthesis of insecticidal agents produced by modular type I PKSs from actinomycete.
Publikováno v:
Journal of Biotechnology. 307:69-76
Branched chain fatty acids (BCFA) are an appealing biorefinery-driven target of fatty acid (FA) production. BCFAs typically have lower melting points compared to straight chain FAs, making them useful in lubricants and biofuels. Actinobacteria, espec
Autor:
Anil Shrestha, Tokutaro Yamaguchi, Amit Kumar Chaudhary, Dipesh Dhakal, Biplav Shrestha, Hye Jin Jung, Jeong Sang Yi, Jae Kyung Sohng, Seung-Young Kim, Anaya Raj Pokhrel, Byung-Gee Kim, Prakash Parajuli
Publikováno v:
Applied Microbiology and Biotechnology. 100:9917-9931
Nargenicin A1, an antibacterial produced by Nocardia sp. CS682 (KCTC 11297BP), demonstrates effective activity against various Gram-positive bacteria. Hence, we attempted to enhance nargenicin A1 production by utilizing the cumulative effect of synth
Publikováno v:
Journal of industrial microbiologybiotechnology. 45(5)
Branched chain amino acids (BCAA) are catabolized into various acyl-CoA compounds, which are key precursors used in polyketide productions. Because of that, BCAA catabolism needs fine tuning of flux balances for enhancing the production of polyketide
Publikováno v:
Biotechnology and Bioengineering. 113:651-660
In silico model-driven analysis using genome-scale model of metabolism (GEM) has been recognized as a promising method for microbial strain improvement. However, most of the current GEM-based strain design algorithms based on flux balance analysis (F
Publikováno v:
Journal of Microbiology and Biotechnology. 25:496-502
Polyketide secondary metabolites share common precursor pools, acyl-CoA. Thus, the effects of engineering strategies for heterologous and native secondary metabolite production are often determined by the measurement of pikromycin in Streptomyces ven
Publikováno v:
Biotechnology Journal. 9:1185-1194
Streptomycetes are industrially and pharmaceutically important bacteria that produce a variety of secondary metabolites including antibiotics. Streptomycetes have a complex metabolic network responsible for the production of secondary metabolites and
Autor:
Min Woo Kim, Yujin Jeong, Jeong Sang Yi, Minsuk Kim, Eun Jung Kim, Byung-Gee Kim, Byung-Kwan Cho
Publikováno v:
ACS synthetic biology. 6(3)
Streptomycetes are Gram-positive mycelial bacteria, which synthesize a wide range of natural products including over two-thirds of the currently available antibiotics. However, metabolic engineering in Streptomyces species to overproduce a vast of na