Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Jeong Min Chung"'
Autor:
Hayeon Lee, Yeseul Lee, Jinseok Lee, Hyeongseop Jeong, Dong Keon Yon, Clarissa L. Durie, Bumhan Ryu, Jeong Min Chung
Publikováno v:
Journal of Analytical Science and Technology, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract The selection of defocus ranges for small datasets in cryo-electron microscopy (cryo-EM) is under-researched. We present a comprehensive benchmark experiment that aimed to evaluate the relationship between contrast, defocus, and resolution,
Externí odkaz:
https://doaj.org/article/6bdbe9f1c3fe4669a5e6f379eaa933a1
Publikováno v:
Journal of Analytical Science and Technology, Vol 13, Iss 1, Pp 1-8 (2022)
Abstract In biology, evolutionary conserved protein sequences show homologous physiological phenotypes in their structures and functions. If the protein has a vital function, its sequence is usually conserved across the species. However, in highly co
Externí odkaz:
https://doaj.org/article/a58a001a8f83429ea8bc9018adb9228f
Autor:
Han-ul Kim, Anahita Vispi Bharda, Jeong Chan Moon, Dooil Jeoung, Jeong Min Chung, Hyun Suk Jung
Publikováno v:
Journal of Analytical Science and Technology, Vol 12, Iss 1, Pp 1-6 (2021)
Abstract Actin is an important unit of the cytoskeletal system, involved in many cellular processes including cell motility, signaling, and intracellular trafficking. Various studies have been undertaken to understand the regulatory mechanisms pertai
Externí odkaz:
https://doaj.org/article/dfd7f466a83e451ba04c80160627bd85
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Actin is a multifunctional biomolecule that forms not only basic structural bodies such as filopodia and lamellipodia, but also large microvilli-like organelles like stereocilia. Actin consists of four sub-domains (S1, S2, S3, and S4), and the “tar
Externí odkaz:
https://doaj.org/article/65ca99a56d7e4a14898db23e494ebeef
Autor:
Michael J Sheedlo, Clarissa L Durie, Jeong Min Chung, Louise Chang, Jacquelyn Roberts, Michele Swanson, Dana Borden Lacy, Melanie D Ohi
Publikováno v:
eLife, Vol 10 (2021)
Legionella pneumophila is an opportunistic pathogen that causes the potentially fatal pneumonia known as Legionnaires’ disease. The pathology associated with infection depends on bacterial delivery of effector proteins into the host via the membran
Externí odkaz:
https://doaj.org/article/769fbc40a033482aa6d6f369888cccee
Publikováno v:
Life, Vol 12, Iss 8, p 1267 (2022)
Cryo-electron microscopy (cryo-EM) has become an unrivaled tool for determining the structure of macromolecular complexes. The biological function of macromolecular complexes is inextricably tied to the flexibility of these complexes. Single particle
Externí odkaz:
https://doaj.org/article/43b80b65b6b74652aa7067a94720dc1b
Publikováno v:
Life, Vol 12, Iss 6, p 843 (2022)
Fascin, a major actin cross-linking protein, is expressed in most vertebrate epithelial tissues. It organizes actin filaments into well-ordered bundles that are responsible for the extension of dynamic membrane protrusions, including microspikes, fil
Externí odkaz:
https://doaj.org/article/c8ed8aa5865248e7a1882ecd04787add
Autor:
Michael J Sheedlo, Jeong Min Chung, Neha Sawhney, Clarissa L Durie, Timothy L Cover, Melanie D Ohi, D Borden Lacy
Publikováno v:
eLife, Vol 9 (2020)
The pathogenesis of Helicobacter pylori-associated gastric cancer is dependent on delivery of CagA into host cells through a type IV secretion system (T4SS). The H. pylori Cag T4SS includes a large membrane-spanning core complex containing five prote
Externí odkaz:
https://doaj.org/article/1dde8d85688348948d757c443b00197a
Autor:
Clarissa L Durie, Michael J Sheedlo, Jeong Min Chung, Brenda G Byrne, Min Su, Thomas Knight, Michele Swanson, D Borden Lacy, Melanie D Ohi
Publikováno v:
eLife, Vol 9 (2020)
Legionella pneumophila is an opportunistic pathogen that causes the potentially fatal pneumonia Legionnaires’ Disease. This infection and subsequent pathology require the Dot/Icm Type IV Secretion System (T4SS) to deliver effector proteins into hos
Externí odkaz:
https://doaj.org/article/4e727e751c3643ba8cf52314be90d2c1
Autor:
Jeong Min Chung, Michael J Sheedlo, Anne M Campbell, Neha Sawhney, Arwen E Frick-Cheng, Dana Borden Lacy, Timothy L Cover, Melanie D Ohi
Publikováno v:
eLife, Vol 8 (2019)
Bacterial type IV secretion systems (T4SSs) are molecular machines that can mediate interbacterial DNA transfer through conjugation and delivery of effector molecules into host cells. The Helicobacter pylori Cag T4SS translocates CagA, a bacterial on
Externí odkaz:
https://doaj.org/article/a09e84dbd1fd47248cd182384fd9c270