Zobrazeno 1 - 10 of 31 pro vyhledávání: '"Jeong M, Kim"'
1
Akademický článek
MICA immune complex formed with alpha 3 domain-specific antibody activates human NK cells in a Fc-dependent manner
Autor: Changchun Du, Jack Bevers, Ryan Cook, T. Noelle Lombana, Kamalakannan Rajasekaran, Marissa Matsumoto, Christoph Spiess, Jeong M. Kim, Zhengmao Ye
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Background One of the mechanisms by which tumors evade immune surveillance is through shedding of the major histocompatibility complex (MHC) class I chain-related protein A and B (MICA/B) from their cell surface. MICA/B are ligands for the a
Externí odkaz: https://doaj.org/article/ff8ffe1b8bda435d9db38f1f06d4754c
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2
Akademický článek
The Kinase Activity of Hematopoietic Progenitor Kinase 1 Is Essential for the Regulation of T Cell Function
Autor: Sairy Hernandez, Jing Qing, Rebecca Hong Thibodeau, Xiangnan Du, Summer Park, Hyang-Mi Lee, Min Xu, Soyoung Oh, Armando Navarro, Meron Roose-Girma, Robert J. Newman, Soren Warming, Michelle Nannini, Deepak Sampath, Jeong M. Kim, Jane L. Grogan, Ira Mellman
Publikováno v: Cell Reports, Vol 25, Iss 1, Pp 80-94 (2018)
Summary: We examined hematopoietic protein kinase 1 (HPK1), whose reliance on scaffold versus kinase functions for negative immune cell regulation is poorly understood and critical to its assessment as a viable drug target. We identify kinase-depende
Externí odkaz: https://doaj.org/article/b83897a71cd24096b600c382ba7050d8
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3
Akademický článek
Tumour and host cell PD-L1 is required to mediate suppression of anti-tumour immunity in mice
Autor: Janet Lau, Jeanne Cheung, Armando Navarro, Steve Lianoglou, Benjamin Haley, Klara Totpal, Laura Sanders, Hartmut Koeppen, Patrick Caplazi, Jacqueline McBride, Henry Chiu, Rebecca Hong, Jane Grogan, Vincent Javinal, Robert Yauch, Bryan Irving, Marcia Belvin, Ira Mellman, Jeong M. Kim, Maike Schmidt
Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
PD-L1, the ligand for T-cell inhibitory receptor PD-1, can be expressed by various cell types in the tumour microenvironment. Here, the authors show that, in mouse models, the expression of PD-L1 from both cancerous and normal host immune cells is im
Externí odkaz: https://doaj.org/article/1afbaeea25fd48089e499f52e8e8af6d
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4
Data from Anti-VEGF Treatment Enhances CD8+ T-cell Antitumor Activity by Amplifying Hypoxia
Autor: Kevin B. Walsh, Jeong M. Kim, Jovencio Borneo, Vincent Javinal, Aurelie Herault, Rajiv Jesudason, Genevive Hernandez, Judy Mak, Patricia E. de Almeida
Antiangiogenic therapies that target the VEGF pathway have been used clinically to combat cancer for over a decade. Beyond having a direct impact on blood vessel development and tumor perfusion, accumulating evidence indicates that these agents also
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::235e4e725cc5aa297c65f359b53e0f02
https://doi.org/10.1158/2326-6066.c.6550410
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6
Akademický článek
CD8+ T cell infiltration in breast and colon cancer: A histologic and statistical analysis.
Autor: James Ziai, Houston N Gilbert, Oded Foreman, Jeffrey Eastham-Anderson, Felix Chu, Mahrukh Huseni, Jeong M Kim
Publikováno v: PLoS ONE, Vol 13, Iss 1, p e0190158 (2018)
The prevalence of cytotoxic tumor infiltrating lymphocytes (TILs) has demonstrated prognostic value in multiple tumor types. In particular, CD8 counts (in combination with CD3 and CD45RO) have been shown to be superior to traditional UICC staging in
Externí odkaz: https://doaj.org/article/23c3a93c2955433186b3b129c97d077b
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7
Anti-VEGF Treatment Enhances CD8+ T-cell Antitumor Activity by Amplifying Hypoxia
Autor: Kevin Walsh, Aurelie Herault, Genevive Hernandez, Patrícia de Almeida, Judy Mak, Jeong M. Kim, Rajiv Jesudason, Vincent Javinal, Jovencio Borneo
Publikováno v: Cancer Immunology Research. 8:806-818
Antiangiogenic therapies that target the VEGF pathway have been used clinically to combat cancer for over a decade. Beyond having a direct impact on blood vessel development and tumor perfusion, accumulating evidence indicates that these agents also
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9bc6b07a7032555f678c5771e7435df3
https://doi.org/10.1158/2326-6066.cir-19-0360
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9
MICA immune complex formed with alpha 3 domain-specific antibody activates human NK cells in a Fc-dependent manner
Autor: Marissa L. Matsumoto, Jack Bevers, Christoph Spiess, Zhengmao Ye, Ryan Cook, Kamalakannan Rajasekaran, T. Noelle Lombana, Jeong M. Kim, Changchun Du
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-13 (2019)
Journal for Immunotherapy of Cancer
Background One of the mechanisms by which tumors evade immune surveillance is through shedding of the major histocompatibility complex (MHC) class I chain-related protein A and B (MICA/B) from their cell surface. MICA/B are ligands for the activating
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa72cec0f06e415e8387aad861c14a7
https://doi.org/10.1186/s40425-019-0687-9
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10
Anti-VEGF Treatment Enhances CD8
Autor: Patricia E, de Almeida, Judy, Mak, Genevive, Hernandez, Rajiv, Jesudason, Aurelie, Herault, Vincent, Javinal, Jovencio, Borneo, Jeong M, Kim, Kevin B, Walsh
Publikováno v: Cancer immunology research. 8(6)
Antiangiogenic therapies that target the VEGF pathway have been used clinically to combat cancer for over a decade. Beyond having a direct impact on blood vessel development and tumor perfusion, accumulating evidence indicates that these agents also
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::60dc0eae081c1809b207fa41161dda9b
https://pubmed.ncbi.nlm.nih.gov/32238381
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