Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jeong Hyang Park"'
Autor:
Jeong Hyang Park, Chang Geon Chung, Sung Soon Park, Davin Lee, Kyung Min Kim, Yeonjin Jeong, Eun Seon Kim, Jae Ho Cho, Yu-Mi Jeon, C-K James Shen, Hyung-Jun Kim, Daehee Hwang, Sung Bae Lee
Publikováno v:
eLife, Vol 9 (2020)
Cytoplasmic accumulation of TDP-43 in motor neurons is the most prominent pathological feature in amyotrophic lateral sclerosis (ALS). A feedback cycle between nucleocytoplasmic transport (NCT) defect and TDP-43 aggregation was shown to contribute to
Externí odkaz:
https://doaj.org/article/46d3424812544032a682295a9de759aa
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Due to their enormous surface area compared to other cell types, neurons face unique challenges in properly handling supply and retrieval of the plasma membrane (PM)—a process termed PM turnover—in their distal areas. Because of the length and ex
Externí odkaz:
https://doaj.org/article/3843018eef52405f8d42f1ac42cce775
Autor:
Chang Geon Chung, Min Jee Kwon, Keun Hye Jeon, Do Young Hyeon, Myeong Hoon Han, Jeong Hyang Park, In Jun Cha, Jae Ho Cho, Kunhyung Kim, Sangchul Rho, Gyu Ree Kim, Hyobin Jeong, Jae Won Lee, TaeSoo Kim, Keetae Kim, Kwang Pyo Kim, Michael D. Ehlers, Daehee Hwang, Sung Bae Lee
Publikováno v:
Cell Reports, Vol 20, Iss 2, Pp 356-369 (2017)
Dendrite aberration is a common feature of neurodegenerative diseases caused by protein toxicity, but the underlying mechanisms remain largely elusive. Here, we show that nuclear polyglutamine (polyQ) toxicity resulted in defective terminal dendrite
Externí odkaz:
https://doaj.org/article/ae951938b8364c18a9c547e11381c797
Autor:
Jae Ho Cho, Min Gu Jo, Eun Seon Kim, Na Yoon Lee, Soon Ha Kim, Chang Geon Chung, Jeong Hyang Park, Sung Bae Lee
Publikováno v:
Molecules and Cells. 45:855-867
Autor:
Sa-Haeng Kang, Young-Jae Song, Yong-Deok Jeon, Dong-Keun Kim, Jeong-Hyang Park, Ju-Ryoun Soh, Jong-Hyun Lee, Christopher Kitalong, Wonnam Kim, Hyo-Jin An, Jae-Ki Chang, Jeonghoon Lee, Jong-Sik Jin
Publikováno v:
Applied Sciences, Vol 11, Iss 4, p 1545 (2021)
Glycyrrhizae radix (GR), a plant commonly referred to as licorice, is used as a medicine and food worldwide. However, the utilization of GR from wild areas has caused desertification and a depletion of natural resources. Environmental restrictions an
Externí odkaz:
https://doaj.org/article/0b16eaf4bd1f4f3eb2593e59ea1e4579
Autor:
Tae Geol Lee, Ga Seul Lee, Jeong Hyang Park, Minh Uyen Thi Le, Sohee Yoon, Chang Geon Chung, Sung Bae Lee, Hyun Jun Jang, Jeong Hee Moon, Jin Gyeong Shon, Joon Sig Choi
Publikováno v:
Journal of the American Society for Mass Spectrometry. 32:2536-2545
Amyotrophic lateral sclerosis (ALS) is a degenerative disease caused by motor neuron damage in the central nervous system, and it is difficult to diagnose early. Drosophila melanogaster is widely used to investigate disease mechanisms and discover bi
Autor:
Chang Geon Chung, In Jun Cha, Hyung-Jun Kim, Byung Su Ko, Eun Seon Kim, Jeong Hyang Park, Jaekwang Kim, Yoon Ha Kim, Chang Man Ha, Sung Soon Park, Sung Bae Lee
Publikováno v:
Human Molecular Genetics
RNA-binding proteins (RBPs) play essential roles in diverse cellular processes through post-transcriptional regulation of RNAs. The subcellular localization of RBPs is thus under tight control, the breakdown of which is associated with aberrant cytop
Autor:
Hyun Jun, Jang, Minh Uyen Thi, Le, Jeong Hyang, Park, Chang Geon, Chung, Jin Gyeong, Shon, Ga Seul, Lee, Jeong Hee, Moon, Sung Bae, Lee, Joon Sig, Choi, Tae Geol, Lee, Sohee, Yoon
Publikováno v:
Journal of the American Society for Mass Spectrometry. 32(10)
Amyotrophic lateral sclerosis (ALS) is a degenerative disease caused by motor neuron damage in the central nervous system, and it is difficult to diagnose early.
Autor:
Jeong Hyang Park, Hyoung Jun Lee, Sohee Yoon, Yong-Hyeon Yim, Jeongkwon Kim, Hyun Jun Jang, Shin Hye Kim, Dan Bee Kim
Publikováno v:
Current Applied Physics. 17:1120-1126
Mass spectrometry (MS) with low temperature plasma (LTP) as an ionization source is one of the widely used ambient methods in analyzing various bio-chemical samples for their detection, identification, differentiation, etc. While the LTP-MS allows se
Autor:
Yoon Ha Kim, Sung Bae Lee, Chang Geon Chung, Jeong Hyang Park, Jaekwang Kim, Hyung-Jun Kim, In Jun Cha, Eun Seon Kim, Chang Man Ha
Accumulation of RNA in the nucleus is one of the pathological features of C9orf72-associated amyotrophic lateral sclerosis and frontotemporal dementia (C9-ALS/FTD), yet its potential toxic cellular consequences remain largely undefined. RNA accumulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162d298972d769b90a51468be946e732