Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Jeong Eun Na"'
Autor:
Chang Hoon Ji, Hee Yeon Kim, Min Ju Lee, Ah Jung Heo, Daniel Youngjae Park, Sungsu Lim, Seulgi Shin, Woo Seung Yang, Chang An Jung, Kun Young Kim, Eun Hye Jeong, Sun Ho Park, Su Bin Kim, Su Jin Lee, Jeong Eun Na, Ji In Kang, Hyung Min Chi, Hyun Tae Kim, Yun Kyung Kim, Bo Yeon Kim, Yong Tae Kwon
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Targeted protein degradation is a promising approach for basic research and therapeutic applications. Here, the authors develop a targeted protein degradation platform called AUTOTAC to degrade oncoproteins and neurodegeneration-associated proteins v
Externí odkaz:
https://doaj.org/article/b40a23bb612c4deeb02c237334426aad
Autor:
Chang Hoon Ji, Hee Yeon Kim, Min Ju Lee, Ah Jung Heo, Daniel Youngjae Park, Sungsu Lim, Seulgi Shin, Srinivasrao Ganipisetti, Woo Seung Yang, Chang An Jung, Kun Young Kim, Eun Hye Jeong, Sun Ho Park, Su Bin Kim, Su Jin Lee, Jeong Eun Na, Ji In Kang, Hyung Min Chi, Hyun Tae Kim, Yun Kyung Kim, Bo Yeon Kim, Yong Tae Kwon
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/21b691d9004c4b9f97ea92429f17feb7
Autor:
Jun Sub Park, Hyun Lee, Bo Woon Choi, Seonggu Ro, Doyoung Lee, Jeong Eun Na, Jeoung-Ho Hong, Jae-Seon Lee, Bong-Woo Kim, Young-Gyu Ko
Publikováno v:
Experimental and Molecular Medicine, Vol 50, Iss 6, Pp 1-12 (2018)
Diabetes: lowering glucose levels by targeting protein interactions A promising drug candidate for type II diabetes targets a protein interaction involved in insulin resistance. In healthy individuals, the insulin receptor substrate 1 (IRS-1) protein
Externí odkaz:
https://doaj.org/article/6e5878df886042439218b557bcf2d955
Publikováno v:
Korean Journal of Ecology and Environment. 54:291-302
Publikováno v:
Korean Journal of Ecology and Environment. 53:11-21
Publikováno v:
Korean Journal of Ecology and Environment. 50:148-156
Autor:
Hyun Geun Lee, Jun Sub Park, Jeoung Ho Hong, Bo Woon Choi, Bong Woo Kim, Seonggu Ro, Young Gyu Ko, Jae Seon Lee, Jeong Eun Na, Doyoung Lee
Publikováno v:
Experimental and Molecular Medicine, Vol 50, Iss 6, Pp 1-12 (2018)
Mitsugumin 53 (MG53) is an E3 ligase that induces insulin receptor substrate-1 (IRS-1) ubiquitination and degradation in skeletal muscle. We previously demonstrated that the pharmaceutical disruption of the MG53-IRS-1 interaction improves insulin sen
Publikováno v:
Tetrahedron Letters. 46:4505-4508
We prepared a brand-new, bowl-shaped molecular architecture in one step from the reaction of ninhydrin and phloroglucinol in acetic acid in excellent yield (95%) in a one-pot reaction and the bipolarofacial nature of this compound was confirmed by it
Publikováno v:
Bulletin of the Korean Chemical Society. 26:319-322
2-Hydroxy-7,8-dihydro-6H-quinolin-5-one skeleton is a useful backbone for the synthesis of numerous biologically interesting compounds such as carbostyrils (2-hydroxyquinolines) or huperzine A analogues, which have shown biological activities includi
Publikováno v:
Bulletin of the Korean Chemical Society. 26:323-326
at the α-position could be carried out easilyand the following Friedel-Crafts type reaction and dehy-dration might occur simultaneously under suitable condi-tions in one-pot. Thus, we examined various reactionconditions, and finally found an effecti