Zobrazeno 1 - 10
of 1 951
pro vyhledávání: '"Jeong A. Hong"'
Publikováno v:
Molecular Therapy: Oncolytics, Vol 27, Iss , Pp 26-47 (2022)
Systemic delivery of oncolytic viruses has been widely regarded as an impractical option for antitumor treatment. Here, we selected two target genes as leading components, and significant therapeutic effects were obtained by simultaneously reducing t
Externí odkaz:
https://doaj.org/article/2161cc64333c47d29a1c95f031682dc9
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-23 (2021)
Abstract Adequate viral replication in tumor cells is the key to improving the anti-cancer effects of oncolytic adenovirus therapy. In this study, we introduced short hairpin RNAs against death-domain associated protein (Daxx), a repressor of adenovi
Externí odkaz:
https://doaj.org/article/6a774af5ee9d4227a13925858eb8e247
Autor:
Lee, Jeong-Eun, Baek, Giseon, Lee, Seokho, Jeong, Jae-Hong, Kim, Chul-Hwan, Aikawa, Yuri, Herczeg, Gregory J., Johnstone, Doug, Tobin, John J.
We present the spectra of Complex Organic Molecules (COMs) detected in HOPS 373SW with the Atacama Large Millimeter/submillimeter Array (ALMA). HOPS 373SW, which is a component of a protostellar binary with a separation of 1500 au, has been discovere
Externí odkaz:
http://arxiv.org/abs/2306.16959
Autor:
Jin-Man Kim, Ho Kyoung Kim, Han Jin Cho, Sung-Ah Moon, Yewon Kim, Jeong Yeon Hong, Seung Hun Lee, Kyunggon Kim, Jung-Min Koh
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Aging and lack of exercise are the most important etiological factors for muscle loss. We hypothesized that new factors that contribute to muscle loss could be identified from ones commonly altered in expression in aged and exercise-limited
Externí odkaz:
https://doaj.org/article/2a97c593a1584ff0a73b520c231c58bc
Publikováno v:
Journal of Neurocritical Care, Vol 17, Iss 1, Pp 24-28 (2024)
Background Branch retinal artery occlusion (BRAO) is characterized by a sudden, painless monocular visual loss. The condition usually has a favorable prognosis but can sometimes cause severe visual loss. Currently, no clinical guidelines are availabl
Externí odkaz:
https://doaj.org/article/b13137e441314e35a363df84d7e83e80
Publikováno v:
IBRO Neuroscience Reports, Vol 16, Iss , Pp 336-344 (2024)
Alzheimer’s disease (AD) is the most common age-related progressive neurodegenerative disorder. The accumulation of amyloid beta-peptide is a neuropathological marker of AD. While melatonin is recognized to have protective effects on aging and neur
Externí odkaz:
https://doaj.org/article/ab66c2bc34cf4c8b9c3bb31fc6ac932e
Autor:
Nikhil Bharti, Leonardo Santos, Marcos Davyt, Stine Behrmann, Marie Eichholtz, Alejandro Jimenez-Sanchez, Jeong S. Hong, Andras Rab, Eric J. Sorscher, Suki Albers, Zoya Ignatova
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Nonsense mutations – the underlying cause of approximately 11% of all genetic diseases – prematurely terminate protein synthesis by mutating a sense codon to a premature stop or termination codon (PTC). An emerging therapeutic strategy t
Externí odkaz:
https://doaj.org/article/7320e409d0a640aa9c9dacd192b22128
Autor:
Joon‐Tae Kim, Ji Sung Lee, Hyunsoo Kim, Beom Joon Kim, Keon‐Joo Lee, Jong‐Moo Park, Kyusik Kang, Soo Joo Lee, Jae Guk Kim, Jae‐Kwan Cha, Dae‐Hyun Kim, Tai Hwan Park, Kyungbok Lee, Jun Lee, Keun‐Sik Hong, Yong‐Jin Cho, Hong‐Kyun Park, Byung‐Chul Lee, Kyung‐Ho Yu, Mi Sun Oh, Dong‐Eog Kim, Jay Chol Choi, Jee‐Hyun Kwon, Wook‐Joo Kim, Dong‐Ick Shin, Kyu Sun Yum, Sung Il Sohn, Jeong‐Ho Hong, Sang‐Hwa Lee, Man‐Seok Park, Wi‐Sun Ryu, Kwang‐Yeol Park, Juneyoung Lee, Jeffrey L. Saver, Hee‐Joon Bae
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 10 (2024)
Background Recent clinical trials established the benefit of dual antiplatelet therapy with aspirin and clopidogrel (DAPT‐AC) in early‐presenting patients with minor ischemic stroke. However, the impact of these trials over time on the use and ou
Externí odkaz:
https://doaj.org/article/cca1701c64834a69a43067ac2a7b9d7c
Autor:
Jangsun Hwang, Hae Woon Jung, Kyung Min Kim, Daun Jeong, Jin Hyuck Lee, Jeong-Ho Hong, Woo Young Jang
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Obesity has been increasing in many regions of the world, including Europe, USA, and Korea. To manage obesity, we should consider it as a disease and apply therapeutic methods for its treatment. Molecular and therapeutic approaches for obesi
Externí odkaz:
https://doaj.org/article/bd587d0e717d45bb8664038ad4b7293f
Publikováno v:
Journal of Neurocritical Care, Vol 16, Iss 2, Pp 85-93 (2023)
Background Acute ischemic stroke is a disease with multiple etiologies. Therefore, identifying the mechanism of acute ischemic stroke is fundamental to its treatment and secondary prevention. The Trial of Org 10172 in Acute Stroke Treatment classific
Externí odkaz:
https://doaj.org/article/748f74386720418db7a814881a1bae64