Intracellular Adhesion Molecule-1 Improves Responsiveness to Immune Checkpoint Inhibitor by Activating CD8 ⁺ T Cells.

Autor: Lee SH; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, 06351, South Korea.; Department of Health Sciences and Technology, Samsung Advanced Institute of Health Sciences and Technology, Sungkyunkwan University, Seoul, 06351, South Korea., Kim Y; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju, 61005, South Korea., Jeon BN; Genome and Company, Pangyo-ro 253, Bundang-gu., Seoungnam-si, Gyeonggi-do, 13486, South Korea., Kim G; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju, 61005, South Korea.; Genome and Company, Pangyo-ro 253, Bundang-gu., Seoungnam-si, Gyeonggi-do, 13486, South Korea., Sohn J; Genome and Company, Pangyo-ro 253, Bundang-gu., Seoungnam-si, Gyeonggi-do, 13486, South Korea., Yoon Y; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju, 61005, South Korea.; Division of Nephrology, Department of Medicine, Chosun University Hospital, Chosun University School of Medicine, Gwangju, 61452, South Korea., Kim S; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju, 61005, South Korea., Kim Y; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju, 61005, South Korea., Kim H; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, 06351, South Korea.; Medical Research Institute, Sungkyunkwan University School of Medicine, Seoul, 06351, South Korea., Cha H; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, 06351, South Korea.; Medical Research Institute, Sungkyunkwan University School of Medicine, Seoul, 06351, South Korea., Lee NE; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, 06351, South Korea.; Department of Health Sciences and Technology, Samsung Advanced Institute of Health Sciences and Technology, Sungkyunkwan University, Seoul, 06351, South Korea., Yang H; Genome and Company, Pangyo-ro 253, Bundang-gu., Seoungnam-si, Gyeonggi-do, 13486, South Korea., Chung JY; Genome and Company, Pangyo-ro 253, Bundang-gu., Seoungnam-si, Gyeonggi-do, 13486, South Korea., Jeong AR; Genome and Company, Pangyo-ro 253, Bundang-gu., Seoungnam-si, Gyeonggi-do, 13486, South Korea., Kim YY; Genome and Company, Pangyo-ro 253, Bundang-gu., Seoungnam-si, Gyeonggi-do, 13486, South Korea., Kim SG; Genome and Company, Pangyo-ro 253, Bundang-gu., Seoungnam-si, Gyeonggi-do, 13486, South Korea., Seo Y; NEX-I Inc., Seoul, 05854, South Korea., Park S; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, 06351, South Korea., Jung HA; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, 06351, South Korea., Sun JM; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, 06351, South Korea., Ahn JS; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, 06351, South Korea., Ahn MJ; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, 06351, South Korea., Park H; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju, 61005, South Korea.; Genome and Company, Pangyo-ro 253, Bundang-gu., Seoungnam-si, Gyeonggi-do, 13486, South Korea., Yoon KW; Genome and Company, Pangyo-ro 253, Bundang-gu., Seoungnam-si, Gyeonggi-do, 13486, South Korea.

Publikováno v: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2023 Jun; Vol. 10 (17), pp. e2204378. Date of Electronic Publication: 2023 Apr 25.

Potential Therapeutic Skin Microbiomes Suppressing Staphylococcus aureus -Derived Immune Responses and Upregulating Skin Barrier Function-Related Genes via the AhR Signaling Pathway.

Autor: Lee E; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju 61005, Korea., Min K; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju 61005, Korea., Ahn H; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju 61005, Korea., Jeon BN; Genome and Company, Pangyo-ro 255, Bundang-gu, Seoungnam-si 13486, Korea., Park S; Genome and Company, Pangyo-ro 255, Bundang-gu, Seoungnam-si 13486, Korea., Yun C; Genome and Company, Pangyo-ro 255, Bundang-gu, Seoungnam-si 13486, Korea., Jeon H; Genome and Company, Pangyo-ro 255, Bundang-gu, Seoungnam-si 13486, Korea., Yeon JS; Genome and Company, Pangyo-ro 255, Bundang-gu, Seoungnam-si 13486, Korea., Kim H; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju 61005, Korea., Park H; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju 61005, Korea.; Genome and Company, Pangyo-ro 255, Bundang-gu, Seoungnam-si 13486, Korea.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 Aug 23; Vol. 23 (17). Date of Electronic Publication: 2022 Aug 23.

Proto-oncoprotein Zbtb7c and SIRT1 repression: implications in high-fat diet-induced and age-dependent obesity.

Autor: Choi WI; Brain Korea FOUR Project for Medical Science, Department of Biochemistry & Molecular Biology, Yonsei University School of Medicine, 50-1 Yonsei-Ro, SeoDaeMoon-Ku, Seoul, 03722, Korea.; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, DaeJeon, 34141, Korea., Yoon JH; Brain Korea FOUR Project for Medical Science, Department of Biochemistry & Molecular Biology, Yonsei University School of Medicine, 50-1 Yonsei-Ro, SeoDaeMoon-Ku, Seoul, 03722, Korea., Choi SH; Brain Korea FOUR Project for Medical Science, Department of Biochemistry & Molecular Biology, Yonsei University School of Medicine, 50-1 Yonsei-Ro, SeoDaeMoon-Ku, Seoul, 03722, Korea., Jeon BN; Brain Korea FOUR Project for Medical Science, Department of Biochemistry & Molecular Biology, Yonsei University School of Medicine, 50-1 Yonsei-Ro, SeoDaeMoon-Ku, Seoul, 03722, Korea., Kim H; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, DaeJeon, 34141, Korea.; KAIST Institute for the BioCentury, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Korea., Hur MW; Brain Korea FOUR Project for Medical Science, Department of Biochemistry & Molecular Biology, Yonsei University School of Medicine, 50-1 Yonsei-Ro, SeoDaeMoon-Ku, Seoul, 03722, Korea. mwhur2@yuhs.ac.

Publikováno v: Experimental & molecular medicine [Exp Mol Med] 2021 May; Vol. 53 (5), pp. 917-932. Date of Electronic Publication: 2021 May 20.

Bifidobacterium bifidum strains synergize with immune checkpoint inhibitors to reduce tumour burden in mice.

Autor: Lee SH; Division of Hematology-Oncology, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.; Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University School of Medicine, Seoul, Korea., Cho SY; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea.; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea., Yoon Y; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju, Korea., Park C; Genome and Company, Gyeonggi-do, Korea., Sohn J; Genome and Company, Gyeonggi-do, Korea., Jeong JJ; Genome and Company, Gyeonggi-do, Korea., Jeon BN; Genome and Company, Gyeonggi-do, Korea., Jang M; Genome and Company, Gyeonggi-do, Korea., An C; Genome and Company, Gyeonggi-do, Korea., Lee S; Genome and Company, Gyeonggi-do, Korea., Kim YY; Genome and Company, Gyeonggi-do, Korea., Kim G; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju, Korea., Kim S; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju, Korea., Kim Y; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju, Korea., Lee GB; Department of Chemistry, Yonsei University, Seoul, Korea., Lee EJ; Genome and Company, Gyeonggi-do, Korea., Kim SG; Genome and Company, Gyeonggi-do, Korea., Kim HS; Division of Hematology-Oncology, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea., Kim Y; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju, Korea., Kim H; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju, Korea., Yang HS; Department of Biotechnology, Hoseo University, Asan, Korea., Kim S; Department of Biotechnology, Hoseo University, Asan, Korea., Kim S; Laboratory Animal Center, Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF), Daegu, Korea., Chung H; Korea Basic Science Institute, Seoul Center, Seoul, Korea., Moon MH; Department of Chemistry, Yonsei University, Seoul, Korea., Nam MH; Korea Basic Science Institute, Seoul Center, Seoul, Korea., Kwon JY; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA., Won S; Department of Public Health Sciences, Seoul National University, Seoul, Korea., Park JS; Laboratory Animal Center, Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF), Daegu, Korea., Weinstock GM; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA., Lee C; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.; Department of Life Science, Ewha Womans University, Seoul, Korea.; The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China., Yoon KW; Genome and Company, Gyeonggi-do, Korea. kwyoon8@gmail.com.; Department of Biotechnology, Hoseo University, Asan, Korea. kwyoon8@gmail.com., Park H; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju, Korea. hspark27@gist.ac.kr.; Genome and Company, Gyeonggi-do, Korea. hspark27@gist.ac.kr.

Publikováno v: Nature microbiology [Nat Microbiol] 2021 Mar; Vol. 6 (3), pp. 277-288. Date of Electronic Publication: 2021 Jan 11.

Catechol inhibits epidermal growth factor-induced epithelial-to-mesenchymal transition and stem cell-like properties in hepatocellular carcinoma cells.

Autor: Lim WC; Korea Food Research Institute, Wanju-gun, Jeollabuk-do, Republic of Korea., Kim H; Department of Biomedical Sciences, Asan Medical Center, AMIST, University of Ulsan College of Medicine, Seoul, Republic of Korea., Kim YJ; Natural Products Research Center, Korea Institute of Science and Technology, Gangneung, Gangwon-do, Republic of Korea., Jeon BN; Genome and Company, Pangyo-ro 253, Bundang-gu, Seongnam-si, Gyeonggi-do, Republic of Korea., Kang HB; Voronoi Research Institute, S 12th F, Songdogwahak-ro 32 (IT center), Yeonsu-gu, Incheon, Republic of Korea., Ko H; HLB Life Science, Teheran-ro 420, Gangnam-gu, Seoul, Republic of Korea. drug9054@naver.com.

Publikováno v: Scientific reports [Sci Rep] 2020 May 06; Vol. 10 (1), pp. 7620. Date of Electronic Publication: 2020 May 06.