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SummaryHistone methyltransferase polycomb repressive complex 2 (PRC2) plays a critical role in cell fate determination, and its catalytic subunit EZH2 is a key oncogenic driver in GCB-DLBCL. EZH2 inhibition in some GCB-DLBCL cell models leads to a gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d861eceffc3d97571339db87d53f0166
Autor:
Bin Masroni MS; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, 117596, Singapore., Ling Eng GW; NUS Centre for Cancer Research, Singapore, 117599, Singapore., Jeon AJ; MiRXES Lab Pte Ltd, Singapore, 138667, Singapore., Gao Y; MiRXES Lab Pte Ltd, Singapore, 138667, Singapore., Cheng H; MiRXES Lab Pte Ltd, Singapore, 138667, Singapore., Leong SM; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, 117596, Singapore.; NUS Centre for Cancer Research, Singapore, 117599, Singapore., Cheong JK; NUS Centre for Cancer Research, Singapore, 117599, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, 117596, Singapore., Hue SS; Department of Pathology, National University Hospital, Singapore, 119077, Singapore. pathue@nus.edu.sg.; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, 117596, Singapore. pathue@nus.edu.sg.; NUS Centre for Cancer Research, Singapore, 117599, Singapore. pathue@nus.edu.sg., Tan SY; Department of Pathology, National University Hospital, Singapore, 119077, Singapore. pattsy@nus.edu.sg.; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, 117596, Singapore. pattsy@nus.edu.sg.; Advanced Molecular Pathology Laboratory, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore, 138673, Singapore. pattsy@nus.edu.sg.
Publikováno v:
Cancer cell international [Cancer Cell Int] 2024 Jan 30; Vol. 24 (1), pp. 48. Date of Electronic Publication: 2024 Jan 30.
Autor:
Jeon AJ; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore., Anene-Nzelu CG; Cardiovascular Disease Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Montreal Heart Institute, Montreal, Quebec, Canada.; Department of Medicine, University of Montreal, Quebec, Canada., Teo YY; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore., Chong SL; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore., Sekar K; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore., Wu L; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore., Chew SC; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore., Chen J; Genome Institute of Singapore, Agency for Science, Technology and Research (A∗STAR), Singapore., Kendarsari RI; Genome Institute of Singapore, Agency for Science, Technology and Research (A∗STAR), Singapore., Lai H; Genome Institute of Singapore, Agency for Science, Technology and Research (A∗STAR), Singapore., Ling WH; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore., Kaya NA; Genome Institute of Singapore, Agency for Science, Technology and Research (A∗STAR), Singapore., Lim JQ; Genome Institute of Singapore, Agency for Science, Technology and Research (A∗STAR), Singapore., Chung AYF; Department of Hepatopancreatobiliary and Transplant Surgery, National Cancer Centre Singapore and Singapore General Hospital, Singapore.; Academic Clinical Programme for Surgery, Duke-NUS Medical School, Singapore., Cheow PC; Department of Hepatopancreatobiliary and Transplant Surgery, National Cancer Centre Singapore and Singapore General Hospital, Singapore.; Academic Clinical Programme for Surgery, Duke-NUS Medical School, Singapore., Kam JH; Department of Hepatopancreatobiliary and Transplant Surgery, National Cancer Centre Singapore and Singapore General Hospital, Singapore.; Academic Clinical Programme for Surgery, Duke-NUS Medical School, Singapore., Madhavan K; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, University Surgical Cluster, National University Health System, Singapore., Kow A; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, University Surgical Cluster, National University Health System, Singapore., Ganpathi IS; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, University Surgical Cluster, National University Health System, Singapore., Lim TKH; Department of Anatomical Pathology, Singapore General Hospital, Singapore., Leow WQ; Department of Anatomical Pathology, Singapore General Hospital, Singapore., Loong S; Department of Anatomical Pathology, Singapore General Hospital, Singapore., Loh TJ; Department of Anatomical Pathology, Singapore General Hospital, Singapore., Wan WK; Department of Anatomical Pathology, Singapore General Hospital, Singapore., Soon GST; Department of Pathology, National University Hospital, Singapore., Pang YH; Department of Pathology, National University Hospital, Singapore., Yoong BK; Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Bee-Lan Ong D; Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Lim J; Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., de Villa VH; Department of Surgery and Center for Liver Health and Transplantation, The Medical City, Pasig City, Philippines., Dela Cruz RD; Department of Laboratory Medicine and Pathology, The Medical City, Pasig City, Philippines., Chanwat R; Hepato-Pancreato-Biliary Surgery Unit, Department of Surgery, National Cancer Institute, Bangkok, Thailand., Thammasiri J; Division of Pathology, National Cancer Institute, Thailand., Bonney GK; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, University Surgical Cluster, National University Health System, Singapore., Goh BKP; Department of Hepatopancreatobiliary and Transplant Surgery, National Cancer Centre Singapore and Singapore General Hospital, Singapore.; Academic Clinical Programme for Surgery, Duke-NUS Medical School, Singapore., Foo RSY; Cardiovascular Disease Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Genome Institute of Singapore, Agency for Science, Technology and Research (A∗STAR), Singapore.; Cardiovascular Research Institute, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Chow PK; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore.; Department of Hepatopancreatobiliary and Transplant Surgery, National Cancer Centre Singapore and Singapore General Hospital, Singapore.; Academic Clinical Programme for Surgery, Duke-NUS Medical School, Singapore.
Publikováno v:
JHEP reports : innovation in hepatology [JHEP Rep] 2023 Feb 26; Vol. 5 (6), pp. 100715. Date of Electronic Publication: 2023 Feb 26 (Print Publication: 2023).
Autor:
Jeon AJ; Department of Hepatopancreatobiliary and Transplant Surgery, Division of Surgery and Surgical Oncology, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore, Singapore., Teo YY; Department of Hepatopancreatobiliary and Transplant Surgery, Division of Surgery and Surgical Oncology, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore, Singapore., Sekar K; Department of Hepatopancreatobiliary and Transplant Surgery, Division of Surgery and Surgical Oncology, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore, Singapore., Chong SL; Department of Hepatopancreatobiliary and Transplant Surgery, Division of Surgery and Surgical Oncology, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore, Singapore., Wu L; Department of Hepatopancreatobiliary and Transplant Surgery, Division of Surgery and Surgical Oncology, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore, Singapore., Chew SC; Department of Hepatopancreatobiliary and Transplant Surgery, Division of Surgery and Surgical Oncology, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore, Singapore., Chen J; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Kendarsari RI; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Lai H; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Ling WH; Department of Hepatopancreatobiliary and Transplant Surgery, Division of Surgery and Surgical Oncology, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore, Singapore., Kaya NA; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Lim JQ; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Ramasamy A; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Oguz G; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Chung AY; Department of Hepatopancreatobiliary and Transplant Surgery, Division of Surgery and Surgical Oncology, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Academic Clinical Programme for Surgery, Duke-NUS Medical School, Singapore, Singapore., Chan CY; Department of Hepatopancreatobiliary and Transplant Surgery, Division of Surgery and Surgical Oncology, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Academic Clinical Programme for Surgery, Duke-NUS Medical School, Singapore, Singapore., Cheow PC; Department of Hepatopancreatobiliary and Transplant Surgery, Division of Surgery and Surgical Oncology, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Academic Clinical Programme for Surgery, Duke-NUS Medical School, Singapore, Singapore., Kam JH; Department of Hepatopancreatobiliary and Transplant Surgery, Division of Surgery and Surgical Oncology, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Academic Clinical Programme for Surgery, Duke-NUS Medical School, Singapore, Singapore., Madhavan K; Division of Hepatobiliary & Pancreatic Surgery, Department of Surgery, University Surgical Cluster, National University Health System, Singapore, Singapore., Kow A; Division of Hepatobiliary & Pancreatic Surgery, Department of Surgery, University Surgical Cluster, National University Health System, Singapore, Singapore., Ganpathi IS; Division of Hepatobiliary & Pancreatic Surgery, Department of Surgery, University Surgical Cluster, National University Health System, Singapore, Singapore., Lim TKH; Department of Anatomical Pathology, Singapore General Hospital, Singapore, 169608, Singapore., Leow WQ; Department of Anatomical Pathology, Singapore General Hospital, Singapore, 169608, Singapore., Loong S; Department of Anatomical Pathology, Singapore General Hospital, Singapore, 169608, Singapore., Loh TJ; Department of Anatomical Pathology, Singapore General Hospital, Singapore, 169608, Singapore., Wan WK; Department of Anatomical Pathology, Singapore General Hospital, Singapore, 169608, Singapore., Soon GST; Department of Pathology, National University Hospital, Singapore, 119074, Singapore., Pang YH; Department of Pathology, National University Hospital, Singapore, 119074, Singapore., Yoong BK; Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Ong DB; Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Lim J; Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., de Villa VH; Department of Surgery and Center for Liver Health and Transplantation, The Medical City, Pasig City, Metro Manila, Philippines., Cruz RDD; Department of Laboratory Medicine and Pathology, The Medical City, Pasig City, Metro Manila, Philippines., Chanwat R; Hepato-Pancreato-Biliary Surgery Unit, Department of Surgery, National Cancer Institute, Bangkok, Thailand., Thammasiri J; Division of Pathology, National Cancer Institute, Bangkok, Thailand., Bonney GK; Division of Hepatobiliary & Pancreatic Surgery, Department of Surgery, University Surgical Cluster, National University Health System, Singapore, Singapore., Goh BKP; Department of Hepatopancreatobiliary and Transplant Surgery, Division of Surgery and Surgical Oncology, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Academic Clinical Programme for Surgery, Duke-NUS Medical School, Singapore, Singapore., Tucker-Kellogg G; Department of Biological Sciences, National University of Singapore, Singapore, Singapore., Foo RSY; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Cardiovascular Disease Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Cardiovascular Research Institute, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Chow PKH; Department of Hepatopancreatobiliary and Transplant Surgery, Division of Surgery and Surgical Oncology, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore. pierce.chow@duke-nus.edu.sg.; Program in Clinical and Translational Liver Cancer Research, Division of Medical Science, National Cancer Center Singapore, Singapore, Singapore. pierce.chow@duke-nus.edu.sg.; Academic Clinical Programme for Surgery, Duke-NUS Medical School, Singapore, Singapore. pierce.chow@duke-nus.edu.sg.
Publikováno v:
BMC cancer [BMC Cancer] 2023 Feb 03; Vol. 23 (1), pp. 118. Date of Electronic Publication: 2023 Feb 03.
Autor:
Jeon AJ; Department of Biological Sciences, National University of Singapore, Singapore, Singapore., Kellogg D; Department of English, Coastal Carolina University, Conway, South Carolina, USA., Khan MA; School of Data Sciences, Perdana University, Selangor, Malaysia., Tucker-Kellogg G; Department of Biological Sciences, National University of Singapore, Singapore, Singapore.; Computational Biology Programme, National University of Singapore, Singapore, Singapore.
Publikováno v:
Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology [Biochem Mol Biol Educ] 2021 Jan; Vol. 49 (1), pp. 140-150. Date of Electronic Publication: 2020 Aug 03.
Autor:
Jeon AJ; Department of Biological Sciences, Faculty of Science, National University of Singapore, 16 Science Drive 4, Singapore, 117558, Singapore., Tucker-Kellogg G; Department of Biological Sciences, Faculty of Science, National University of Singapore, 16 Science Drive 4, Singapore, 117558, Singapore. dbsgtk@nus.edu.sg.; Computational Biology Programme, Faculty of Science, National University of Singapore, 21 Lower Kent Ridge Road, Singapore, 11907, Singapore. dbsgtk@nus.edu.sg.
Publikováno v:
BMC genomics [BMC Genomics] 2020 Nov 18; Vol. 21 (Suppl 10), pp. 614. Date of Electronic Publication: 2020 Nov 18.
Autor:
Lim TG; Advanced Institutes of Convergence Technology, Seoul National University, Suwon 443-270, Republic of Korea., Jeon AJ; Advanced Institutes of Convergence Technology, Seoul National University, Suwon 443-270, Republic of Korea., Yoon JH; Department of Bioscience and Biotechnology, Konkuk University, Seoul 143-701, Republic of Korea., Song D; WCU Biomodulation Major, Department of Agricultural Biotechnology and Institute on Aging, Seoul National University, Seoul 151-921, Republic of Korea., Kim JE; WCU Biomodulation Major, Department of Agricultural Biotechnology and Institute on Aging, Seoul National University, Seoul 151-921, Republic of Korea., Kwon JY; Advanced Institutes of Convergence Technology, Seoul National University, Suwon 443-270, Republic of Korea., Kim JR; Advanced Institutes of Convergence Technology, Seoul National University, Suwon 443-270, Republic of Korea., Kang NJ; School of Food Science and Biotechnology, Kyungpook National University, Daegu 702-701, Republic of Korea., Park JS; Skin Research Institute, Amorepacific Corporation R&D Center, Yongin 341-1, Republic of Korea., Yeom MH; Skin Research Institute, Amorepacific Corporation R&D Center, Yongin 341-1, Republic of Korea., Oh DK; Department of Bioscience and Biotechnology, Konkuk University, Seoul 143-701, Republic of Korea., Lim Y; Department of Bioscience and Biotechnology, Konkuk University, Seoul 143-701, Republic of Korea., Lee CC; Department of Food Science, Cornell University, Ithaca, NY 14850, USA., Lee CY; Department of Food Science, Cornell University, Ithaca, NY 14850, USA., Lee KW; Advanced Institutes of Convergence Technology, Seoul National University, Suwon 443-270, Republic of Korea.
Publikováno v:
International journal of molecular medicine [Int J Mol Med] 2015 May; Vol. 35 (5), pp. 1388-94. Date of Electronic Publication: 2015 Mar 02.
Autor:
Jeon AJ; National Core Research Center (NCRC), Pusan National University , Pusan 609-735, Korea., Kim SJ; Samsung Electronics Co., Ltd. , Suwon 443-742, Korea., Lee SH; Korea Institute of Materials Science , Changwon 642-831, Korea., Kang CY; National Core Research Center (NCRC), Pusan National University , Pusan 609-735, Korea e-mail: kangcy@pusan.ac.kr.
Publikováno v:
Journal of electronic packaging [J Electron Packag] 2013 Jun; Vol. 135 (2), pp. 0210061-210065. Date of Electronic Publication: 2013 Mar 28.
Autor:
Yoon JH; Department of Bioscience and Biotechnology, Bio/Molecular Informatics Center, Konkuk University, Seoul, Republic of Korea., Lim TG, Lee KM, Jeon AJ, Kim SY, Lee KW
Publikováno v:
Journal of agricultural and food chemistry [J Agric Food Chem] 2011 Jan 12; Vol. 59 (1), pp. 222-8. Date of Electronic Publication: 2010 Dec 02.