Analysis of cholesterol export from endo-lysosomes by Niemann Pick C2 protein using combined fluorescence and X-ray microscopy

Autor: Gerd Schneider, Frederik W. Lund, Christian W. Heegaard, Maria Szomek, Peter Guttmann, Jensen Mlv, Stephan Werner, Sergey Kapishnikov, Alice Dupont, Daniel Wüstner, Gitte Nielsen, James G. McNally

Publikováno v: Dupont, A, Lund, F W, Jensen, M L V, Szomek, M, Nielsen, G K, Heegaard, C W, Guttmann, P, Werner, S, McNally, J, Schneider, G, Kapishnikov, S & Wüstner, D 2018, ' Analysis of cholesterol export from endo-lysosomes by Niemann Pick C2 protein using combined fluorescence and X-ray microscopy ', BioRxiv . https://doi.org/10.1101/462481

The Niemann-Pick C2 protein (NPC2) is a sterol transfer protein in late endosomes and lysosomes (LE/LYSs). How its capacity to transport cholesterol between membranes is linked to endo-lysosomal membrane trafficking is not known. Using quantitative f

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https://portal.findresearcher.sdu.dk/da/publications/427dd2f1-8c32-4763-835e-9fc2f75af605

Correction: Jensen et al. Prior Antibiotic Use Increases Risk of Urinary Tract Infections Caused by Resistant Escherichia coli among Elderly in Primary Care: A Case-Control Study. Antibiotics 2022, 11 , 1382.

Autor: Jensen MLV; Department of Clinical Microbiology, Copenhagen University Hospital-Herlev and Gentofte, 2730 Herlev, Denmark.; The Research Unit for General Practice and Section of General Practice, Department of Public Health, University of Copenhagen, 1014 Copenhagen, Denmark., Siersma V; The Research Unit for General Practice and Section of General Practice, Department of Public Health, University of Copenhagen, 1014 Copenhagen, Denmark., Søes LM; Department of Clinical Microbiology, Copenhagen University Hospital-Hvidovre and Amager, 2650 Hvidovre, Denmark., Nicolaisdottir D; The Research Unit for General Practice and Section of General Practice, Department of Public Health, University of Copenhagen, 1014 Copenhagen, Denmark., Bjerrum L; The Research Unit for General Practice and Section of General Practice, Department of Public Health, University of Copenhagen, 1014 Copenhagen, Denmark., Holzknecht BJ; Department of Clinical Microbiology, Copenhagen University Hospital-Herlev and Gentofte, 2730 Herlev, Denmark.; Department of Clinical Medicine, University of Copenhagen, 2200 Copenhagen, Denmark.

Publikováno v: Antibiotics (Basel, Switzerland) [Antibiotics (Basel)] 2023 Feb 14; Vol. 12 (2). Date of Electronic Publication: 2023 Feb 14.

Trend in antibiotic prescription to children aged 0-6 years old in the capital region of Denmark between 2009 and 2018: Differences between municipalities and association with socioeconomic composition.

Autor: Larsen SB; Department of Public Health, Section of General Practice and Research Unit for General Practice, University of Copenhagen, Copenhagen, Denmark., Jensen MLV; Department of Public Health, Section of General Practice and Research Unit for General Practice, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Microbiology, Herlev and Gentofte Hospital, University of Copenhagen, Herlev, Denmark., Bjerrum L; Department of Public Health, Section of General Practice and Research Unit for General Practice, University of Copenhagen, Copenhagen, Denmark., Siersma V; Department of Public Health, Section of General Practice and Research Unit for General Practice, University of Copenhagen, Copenhagen, Denmark., Bang CW; Department of Public Health, Section of General Practice and Research Unit for General Practice, University of Copenhagen, Copenhagen, Denmark., Jensen JN; Department of Clinical Microbiology, Herlev and Gentofte Hospital, University of Copenhagen, Herlev, Denmark.

Publikováno v: The European journal of general practice [Eur J Gen Pract] 2021 Dec; Vol. 27 (1), pp. 257-263.

Niemann-Pick C2 protein regulates sterol transport between plasma membrane and late endosomes in human fibroblasts.

Autor: Berzina Z; Department of Biochemistry and Molecular Biology, VILLUM Center for Bioanalytical Sciences, University of Southern Denmark, DK-5230 Odense M, Denmark., Solanko LM; Department of Biochemistry and Molecular Biology, VILLUM Center for Bioanalytical Sciences, University of Southern Denmark, DK-5230 Odense M, Denmark; Orphazyme ApS, Ole Maales Vej 3, 2200 Copenhagen N, Denmark., Mehadi AS; Department of Biochemistry and Molecular Biology, VILLUM Center for Bioanalytical Sciences, University of Southern Denmark, DK-5230 Odense M, Denmark., Jensen MLV; Department of Biochemistry and Molecular Biology, VILLUM Center for Bioanalytical Sciences, University of Southern Denmark, DK-5230 Odense M, Denmark., Lund FW; Department of Biochemistry and Molecular Biology, VILLUM Center for Bioanalytical Sciences, University of Southern Denmark, DK-5230 Odense M, Denmark., Modzel M; Department of Biochemistry and Molecular Biology, VILLUM Center for Bioanalytical Sciences, University of Southern Denmark, DK-5230 Odense M, Denmark., Szomek M; Department of Biochemistry and Molecular Biology, VILLUM Center for Bioanalytical Sciences, University of Southern Denmark, DK-5230 Odense M, Denmark., Solanko KA; Department of Biochemistry and Molecular Biology, VILLUM Center for Bioanalytical Sciences, University of Southern Denmark, DK-5230 Odense M, Denmark., Dupont A; Department of Biochemistry and Molecular Biology, VILLUM Center for Bioanalytical Sciences, University of Southern Denmark, DK-5230 Odense M, Denmark., Nielsen GK; Department of Molecular Biology and Genetics, University of Aarhus, DK-8000 Aarhus C, Denmark., Heegaard CW; Department of Molecular Biology and Genetics, University of Aarhus, DK-8000 Aarhus C, Denmark., Ejsing CS; Department of Biochemistry and Molecular Biology, VILLUM Center for Bioanalytical Sciences, University of Southern Denmark, DK-5230 Odense M, Denmark., Wüstner D; Department of Biochemistry and Molecular Biology, VILLUM Center for Bioanalytical Sciences, University of Southern Denmark, DK-5230 Odense M, Denmark. Electronic address: wuestner@bmb.sdu.dk.

Publikováno v: Chemistry and physics of lipids [Chem Phys Lipids] 2018 Jul; Vol. 213, pp. 48-61. Date of Electronic Publication: 2018 Mar 23.