Antigen Presentation of Vacuolated Apicomplexans--Two Gateways to a Vaccine Antigen

Autor: Jensen, KDC

Publikováno v: Jensen, KDC. (2016). Antigen Presentation of Vacuolated Apicomplexans--Two Gateways to a Vaccine Antigen.. Trends in parasitology, 32(2), 88-90. doi: 10.1016/j.pt.2015.12.011. UC Merced: Retrieved from: http://www.escholarship.org/uc/item/2d50d91b

For parasites that sequester themselves within a vacuole, new rules governing antigen presentation are coming into focus. Components of the host's autophagy machinery and the parasite's membranous nanotubular network within the parasitophorous vacuol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::a2d53e6acef3f4b3ae9fd97c5f90909a
http://www.escholarship.org/uc/item/2d50d91b

The GPI sidechain of Toxoplasma gondii inhibits parasite pathogenesis.

Autor: Alvarez JA; Department of Molecular and Cell Biology, School of Natural Sciences, University of California, Merced, California, USA.; Quantitative and Systems Biology Graduate Program, University of California, Merced, California, USA., Gas-Pascual E; Department of Biochemistry and Molecular Biology, Center for Tropical and Emerging Global Diseases, and Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA., Malhi S; Department of Molecular and Cell Biology, School of Natural Sciences, University of California, Merced, California, USA., Sánchez-Arcila JC; Department of Molecular and Cell Biology, School of Natural Sciences, University of California, Merced, California, USA., Njume FN; Department of Molecular and Cell Biology, School of Natural Sciences, University of California, Merced, California, USA., van der Wel H; Department of Biochemistry and Molecular Biology, Center for Tropical and Emerging Global Diseases, and Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA., Zhao Y; Department of Medicine and Center for Immunity and Inflammation, New Jersey Medical School, Rutgers University, Newark, New Jersey, USA., García-López L; Department of Molecular and Cell Biology, School of Natural Sciences, University of California, Merced, California, USA.; Quantitative and Systems Biology Graduate Program, University of California, Merced, California, USA., Ceron G; Department of Molecular and Cell Biology, School of Natural Sciences, University of California, Merced, California, USA., Posada J; Department of Molecular and Cell Biology, School of Natural Sciences, University of California, Merced, California, USA., Souza SP; Department of Molecular and Cell Biology, School of Natural Sciences, University of California, Merced, California, USA.; Quantitative and Systems Biology Graduate Program, University of California, Merced, California, USA., Yap GS; Department of Medicine and Center for Immunity and Inflammation, New Jersey Medical School, Rutgers University, Newark, New Jersey, USA., West CM; Department of Biochemistry and Molecular Biology, Center for Tropical and Emerging Global Diseases, and Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA., Jensen KDC; Department of Molecular and Cell Biology, School of Natural Sciences, University of California, Merced, California, USA.; Health Sciences Research Institute, University of California, Merced, California, USA.

Publikováno v: MBio [mBio] 2024 Oct 16; Vol. 15 (10), pp. e0052724. Date of Electronic Publication: 2024 Sep 20.

Variation in CD8 T cell IFNγ differentiation to strains of Toxoplasma gondii is characterized by small effect QTLs with contribution from ROP16.

Autor: Kongsomboonvech AK; Department of Molecular and Cell Biology, University of California, Merced, Merced, CA, United States.; Quantitative Systems Biology Graduate Program, University of California, Merced, Merced, CA, United States., García-López L; Department of Molecular and Cell Biology, University of California, Merced, Merced, CA, United States.; Quantitative Systems Biology Graduate Program, University of California, Merced, Merced, CA, United States., Njume F; Department of Molecular and Cell Biology, University of California, Merced, Merced, CA, United States., Rodriguez F; Department of Molecular and Cell Biology, University of California, Merced, Merced, CA, United States., Souza SP; Department of Molecular and Cell Biology, University of California, Merced, Merced, CA, United States.; Quantitative Systems Biology Graduate Program, University of California, Merced, Merced, CA, United States., Rosenberg A; The Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, United States., Jensen KDC; Department of Molecular and Cell Biology, University of California, Merced, Merced, CA, United States.; Health Sciences Research Institute, University of California, Merced, Merced, CA, United States.

Publikováno v: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2023 May 23; Vol. 13, pp. 1130965. Date of Electronic Publication: 2023 May 23 (Print Publication: 2023).

Genetic mapping reveals Nfkbid as a central regulator of humoral immunity to Toxoplasma gondii.

Autor: Souza SP; School of Natural Sciences, Department of Molecular and Cell Biology, University of California, Merced, Merced, California, United States of America.; Graduate Program in Quantitative and Systems Biology, University of California, Merced, Merced, California, United States of America., Splitt SD; School of Natural Sciences, Department of Molecular and Cell Biology, University of California, Merced, Merced, California, United States of America.; Graduate Program in Quantitative and Systems Biology, University of California, Merced, Merced, California, United States of America., Sànchez-Arcila JC; School of Natural Sciences, Department of Molecular and Cell Biology, University of California, Merced, Merced, California, United States of America., Alvarez JA; School of Natural Sciences, Department of Molecular and Cell Biology, University of California, Merced, Merced, California, United States of America.; Graduate Program in Quantitative and Systems Biology, University of California, Merced, Merced, California, United States of America., Wilson JN; School of Natural Sciences, Department of Molecular and Cell Biology, University of California, Merced, Merced, California, United States of America.; Graduate Program in Quantitative and Systems Biology, University of California, Merced, Merced, California, United States of America., Wizzard S; School of Natural Sciences, Department of Molecular and Cell Biology, University of California, Merced, Merced, California, United States of America., Luo Z; Center for Immunology & Infectious Diseases, and Department of Pathology, Microbiology and Immunology, University of California, Davis, Davis, California, United States of America., Baumgarth N; Center for Immunology & Infectious Diseases, and Department of Pathology, Microbiology and Immunology, University of California, Davis, Davis, California, United States of America., Jensen KDC; School of Natural Sciences, Department of Molecular and Cell Biology, University of California, Merced, Merced, California, United States of America.; Health Science Research Institute, University of California, Merced, Merced, California, United States of America.

Publikováno v: PLoS pathogens [PLoS Pathog] 2021 Dec 06; Vol. 17 (12), pp. e1010081. Date of Electronic Publication: 2021 Dec 06 (Print Publication: 2021).

Naïve CD8 T cell IFNγ responses to a vacuolar antigen are regulated by an inflammasome-independent NLRP3 pathway and Toxoplasma gondii ROP5.

Autor: Kongsomboonvech AK; Department of Molecular and Cell Biology, University of California, Merced, Merced, California, United States of America., Rodriguez F; Department of Molecular and Cell Biology, University of California, Merced, Merced, California, United States of America., Diep AL; Department of Molecular and Cell Biology, University of California, Merced, Merced, California, United States of America., Justice BM; Department of Molecular and Cell Biology, University of California, Merced, Merced, California, United States of America., Castallanos BE; Department of Molecular and Cell Biology, University of California, Merced, Merced, California, United States of America., Camejo A; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America., Mukhopadhyay D; Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, Davis, California, United States of America., Taylor GA; Departments of Medicine; Molecular Genetics and Microbiology; and Immunology; and Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, North Carolina, United States of America.; Geriatric Research, Education, and Clinical Center, Durham VA Health Care System, Durham, North Carolina, United States of America., Yamamoto M; Department of Immunoparasitology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan., Saeij JPJ; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.; Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, Davis, California, United States of America., Reese ML; Department of Pharmacology, University of Texas, Southwestern Medical Center, Dallas, Texas, United States of America., Jensen KDC; Department of Molecular and Cell Biology, University of California, Merced, Merced, California, United States of America.; Health Sciences Research Institute, University of California, Merced, Merced, California, United States of America.

Publikováno v: PLoS pathogens [PLoS Pathog] 2020 Aug 27; Vol. 16 (8), pp. e1008327. Date of Electronic Publication: 2020 Aug 27 (Print Publication: 2020).