Rifampicin does not reduce moxifloxacin concentrations at the site of infection and may not improve treatment outcome of a one-stage exchange surgery protocol of implant-associated osteomyelitis lesions in a porcine model.

Autor: Vittrup S; Aarhus Denmark Microdialysis Research (ADMIRE), Orthopaedic Research Laboratory, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Jensen LK; Department of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg, Denmark., Hartmann KT; Department of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg, Denmark., Aalbaek B; Department of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg, Denmark., Hanberg P; Aarhus Denmark Microdialysis Research (ADMIRE), Orthopaedic Research Laboratory, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Slater J; Aarhus Denmark Microdialysis Research (ADMIRE), Orthopaedic Research Laboratory, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Hvistendahl MA; Aarhus Denmark Microdialysis Research (ADMIRE), Orthopaedic Research Laboratory, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Stilling M; Aarhus Denmark Microdialysis Research (ADMIRE), Orthopaedic Research Laboratory, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Department of Orthopaedic Surgery, Aarhus University Hospital, Aarhus, Denmark., Jørgensen NP; Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark., Bue M; Aarhus Denmark Microdialysis Research (ADMIRE), Orthopaedic Research Laboratory, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Department of Orthopaedic Surgery, Aarhus University Hospital, Aarhus, Denmark.

Publikováno v: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica [APMIS] 2024 Mar; Vol. 132 (3), pp. 198-209. Date of Electronic Publication: 2023 Dec 28.

Bone infection evolution.

Autor: Jensen LK; Department of Veterinary and Animal Science, Faculty of Health and Medical Science, University of Copenhagen, Denmark. Electronic address: Louise-k@sund.ku.dk., Hartmann KT; Department of Veterinary and Animal Science, Faculty of Health and Medical Science, University of Copenhagen, Denmark., Witzmann F; Museum für Naturkunde, Leibniz-Institut für Evolutions- und Biodiversitätsforschung, Berlin, Germany., Asbach P; Department of Radiology, Charité - Universitätsmedizin Berlin, Germany., Stewart PS; Department of Chemical and Biological Engineering, Center for Biofilm Engineering, Montana State University, Bozeman, MT, USA.

Publikováno v: Injury [Injury] 2024 Nov; Vol. 55 Suppl 6, pp. 111826.

Eradication of Staphylococcus aureus in Implant-Associated Osteomyelitis by an Injectable In Situ-Forming Depot Antibiotics Delivery System.

Autor: Fuglsang-Madsen AJ; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark., Henriksen NL; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.; Department of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg, Denmark., Chávez ES; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark., Kvich LA; Costerton Biofilm Centre, Institute of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark., Birch JKM; Department of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg, Denmark., Hartmann KT; Department of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg, Denmark., Eriksen T; Department of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg, Denmark., Bjarnsholt T; Costerton Biofilm Centre, Institute of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Microbiology, University of Copenhagen, Copenhagen, Denmark., Gottlieb H; Department of Orthopedic Surgery, Herlev Hospital, Herlev, Denmark., Andresen TL; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark., Jensen LK; Department of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg, Denmark., Henriksen JR; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark., Hansen AE; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark.

Publikováno v: The Journal of infectious diseases [J Infect Dis] 2024 Sep 23; Vol. 230 (3), pp. 614-623.

Bladder catheterization improves bacterial interference with asymptomatic Escherichia coli 83972 in an experimental porcine model of urinary tract infection.

Autor: Stærk K; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Clinical Microbiology, Odense University Hospital, Odense, Denmark., Andersen K; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Urology, Odense University Hospital, Odense, Denmark., Hjelmager JS; Department of Clinical Research, University of Southern Denmark, Odense, Denmark., Jensen LK; Pathobiological Sciences, University of Copenhagen, Copenhagen, Denmark., Jørgensen BM; Pathobiological Sciences, University of Copenhagen, Copenhagen, Denmark., Møller-Jensen J; Department of Biomedicine and Molecular Biology, University of Southern Denmark, Denmark., Lund L; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Urology, Odense University Hospital, Odense, Denmark., Andersen TE; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Clinical Microbiology, Odense University Hospital, Odense, Denmark.

Publikováno v: The Journal of infectious diseases [J Infect Dis] 2024 Aug 20. Date of Electronic Publication: 2024 Aug 20.

The potential of sheep in preclinical models for bone infection research - A systematic review.

Autor: Beagan MLC; Odense University Hospital & University of Southern Denmark, Odense, Denmark., Dreyer CH; Odense University Hospital & University of Southern Denmark, Odense, & Slagelse Hospital, Slagelse, Denmark., Jensen LK; University of Copenhagen, Copenhagen, Denmark., Jensen HE; University of Copenhagen, Copenhagen, Denmark., Andersen TE; Odense University Hospital & University of Southern Denmark, Odense, Denmark., Overgaard S; Bispebjerg Hospital & University of Copenhagen, Copenhagen, Denmark., Ding M; Odense University Hospital & University of Southern Denmark, Odense, Denmark.

Publikováno v: Journal of orthopaedic translation [J Orthop Translat] 2024 Mar 19; Vol. 45, pp. 120-131. Date of Electronic Publication: 2024 Mar 19 (Print Publication: 2024).