Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jens-Kerim Ergüden"'
Autor:
Mario Jeske, Gunter Karig, Jörg Keldenich, Hartmut Beck, Felix Oehme, Kai Dr. Thede, Ingo Hartung, Metin Akbaba, Hans-Christian Militzer, Jens-Kerim Ergüden, Friederike Stoll, Ingo Flamme, Uwe Thuss
Publikováno v:
ChemMedChem. 13:988-1003
Small-molecule inhibitors of hypoxia-inducible factor prolyl hydroxylases (HIF-PHs) are currently under clinical development as novel treatment options for chronic kidney disease (CKD) associated anemia. Inhibition of HIF-PH mimics hypoxia and leads
Autor:
Metin Akbaba, Uwe Thuss, Kai Dr. Thede, Gunter Karig, Jörg Keldenich, Friederike Stoll, Hans-Christian Militzer, Ingo Flamme, Mario Jeske, Jens-Kerim Ergüden, Felix Oehme, Ingo Hartung, Hartmut Beck
Publikováno v:
ChemMedChem. 13:981-981
Autor:
Ernst Schaumann, Jens-Kerim Ergüden
Publikováno v:
Synthesis. 1996:707-710
Autor:
Santiago Figueroa-Pérez, Heike Gielen-Haertwig, Jens-Kerim Ergüden, Adam Nitsche, Rolf Grosser, Lars Bärfacker, Peter Kolkhof, Alexander Hillisch, Joachim Mittendorf, Alexander Kuhl, Heike Heckroth, Holger Paulsen, Karl-Heinz Schlemmer, Johannes Platzek
Publikováno v:
ChemMedChem. 7(8)
Aldosterone is a hormone that exerts manifold deleterious effects on the kidneys, blood vessels, and heart which can lead to pathophysiological consequences. Inhibition of the mineralocorticoid receptor (MR) is a proven therapeutic concept for the ma
Autor:
Kentaro Hashimoto, Hideki Tsujishita, Stefan Weigand, Thomas Krahn, Jens-Kerim Ergüden, Johannes-Peter Stasch, Christian Schröder, Stephan Siegel, Michael Brands, Nagahiro Yoshida, Dirk Heimbach
Publikováno v:
ChemMedChem. 1(1)
Inhibition of the metalloprotease ECE-1 may be beneficial for the treatment of coronary heart disease, cancer, renal failure, and urological disorders. A novel class of indole-based ECE inhibitors was identified by high throughput screening. Optimiza
Autor:
Jens-Kerim Ergüden, Harold W. Moore
Publikováno v:
Organic letters. 1(3)
[formula: see text] This paper describes a new tandem reaction sequence leading to angularly fused polyquinanes from squaric acid-derived bicyclo[6.3.0]-undecadienediones. Such compounds undergo a dual Michael addition. The enolate form in the first
Autor:
Rolf Grosser, Johannes Platzek, Heike Heckroth, Jens-Kerim Ergüden, Joachim Mittendorf, Adam Nitsche, Lars Bärfacker, Peter Kolkhof, Alexander Kuhl, Alexander Hillisch, Karl-Heinz Schlemmer, Holger Paulsen, Heike Gielen-Haertwig, Santiago Figueroa-Pérez
Publikováno v:
ChemMedChem. 7:1301-1301