Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jens Wenkel"'
Publikováno v:
Expert Opinion on Biological Therapy. 2:671-676
The 93rd Annual Meeting of the American Association of Cancer Research was held in San Francisco, CA, USA. It was one of the largest conferences of its kind covering all aspects of cancer research with ∼ 6000 scientific presentations over a period
Autor:
Yan Zeng, Rong Xiang, Gerhard Gaedicke, Jens Wenkel, Holger N. Lode, Jikai Jiang, Nicole Huebener
Publikováno v:
Cancer letters. 228(1-2)
The induction of tumor protective immunity against neuroblastoma remains a major challenge for active immunotherapy. Fractalkine is a unique Th1 CX3C chemokine known to induce adhesion and migration of leukocytes mediated by both, a membrane-bound an
Autor:
Nicole Huebener, Gerhard Gaedicke, A Strandsby, B Lange, Ulrike Schroeder, Jens Wenkel, J Jikai, Holger N. Lode, Wolfgang Wrasidlo
Publikováno v:
Cancer letters. 197(1-2)
Effective chemotherapy in neuroblastoma is limited by poor anti-tumor efficacy, systemic toxicity and the induction of drug resistance. Here, we provide further evidence that a hydrolytic activated prodrug design may overcome these problems. For this
Autor:
Jens Wenkel, Kathrin M. Bernt, Andreas G. Niethammer, Lueder Wiebusch, Ralph A. Reisfeld, Christian Hagemeier, Roey J. Amir, Gerhard Gaedicke, Bjoern Lange, Ulrike Schroeder, Jiang Jikai, Holger N. Lode, Nicole Huebener, Wolfgang Wrasidlo, Doron Shabat
Publikováno v:
Blood. 102(1)
Effective therapy of high-risk leukemia with established cytotoxic drugs may be limited by poor antitumor efficacy, systemic toxicity, and the induction of drug resistance. Here, we provide the first evidence that hydrolytically activated prodrugs ma