Zobrazeno 1 - 10
of 227
pro vyhledávání: '"Jens W. Fischer"'
Autor:
Zheng Fan, Mara Karakone, Shunmugam Nagarajan, Nadine Nagy, Wiebke Mildenberger, Ekaterina Petrova, Laura Catharina Hinte, Mitchell Bijnen, Philipp Häne, Eric Nelius, Jing Chen, Irina Ferapontova, Ferdinand von Meyenn, Francesco Trepiccione, Mesut Berber, David Penton Ribas, Anne Eichmann, Maria-Christina Zennaro, Norihiko Takeda, Jens W. Fischer, Ariadni Spyroglou, Martin Reincke, Felix Beuschlein, Johannes Loffing, Melanie Greter, Christian Stockmann
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114395- (2024)
Summary: Macrophages play crucial roles in organ-specific functions and homeostasis. In the adrenal gland, macrophages closely associate with sinusoidal capillaries in the aldosterone-producing zona glomerulosa. We demonstrate that macrophages preser
Externí odkaz:
https://doaj.org/article/02b69b219d364673aaf81f6bfedf2bb0
Autor:
Kim J. Krott, Friedrich Reusswig, Matthias Dille, Evelyn Krüger, Simone Gorressen, Saoussen Karray, Amin Polzin, Malte Kelm, Jens W. Fischer, Margitta Elvers
Publikováno v:
Biomedicines, Vol 12, Iss 5, p 1077 (2024)
Acute myocardial infarction (AMI) is one of the leading causes of death worldwide. Cell apoptosis in the myocardium plays an important role in ischemia and reperfusion (I/R) injury, leading to cardiac damage and dysfunction. Platelets are major playe
Externí odkaz:
https://doaj.org/article/60335821fb874b1789797d31e987aa92
Autor:
Christian Vogeley, Özer Degistirici, Sören Twarock, Jessica Wladarz, Oliver Reiners, Tobias Gorges, Jens W. Fischer, Roland Meisel, Katharina Gorges
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Metastatic spread of cancer cells into a pre-metastatic niche is highly dependent on a supporting microenvironment. Human bone marrow-derived mesenchymal stem cells (bmMSCs) contribute to the tumor microenvironment and promote cancer metasta
Externí odkaz:
https://doaj.org/article/def6adfc88534c20802dc71d37a4ba04
Autor:
Luzhou Wang, Heba Zabri, Simone Gorressen, Dominik Semmler, Christian Hundhausen, Jens W. Fischer, Katharina Bottermann
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The incidence of heart failure after myocardial infarction (MI) remains high and the underlying causes are incompletely understood. The crosstalk between heart and adipose tissue and stimulated lipolysis has been identified as potential driver of hea
Externí odkaz:
https://doaj.org/article/362ba19ed7cd456f85e90c3253e24832
Autor:
Meike Klier, Simone Gorressen, Marc-Andre Urbahn, David Barbosa, Margriet Ouwens, Jens W. Fischer, Margitta Elvers
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Phospholipase D1 is a regulator of tumor necrosis factor-α expression and release upon LPS-induced sepsis and following myocardial infarction (MI). Lack of PLD1 leads to a reduced TNF-α mediated inflammatory response and to enhanced infarct size wi
Externí odkaz:
https://doaj.org/article/770335fccbc747c4b5b6db508ce1108f
Autor:
Marco Piroth, Daniel J Gorski, Christian Hundhausen, Anne Petz, Simone Gorressen, Dominik Semmler, Heba Zabri, Sonja Hartwig, Stefan Lehr, Malte Kelm, Christian Jung, Jens W. Fischer
Publikováno v:
Matrix Biology. 112:116-131
Dysregulated extracellular matrix (ECM) is a hallmark of adverse cardiac remodeling after myocardial infarction (MI). Previous work from our laboratory suggests that synthesis of the major ECM component hyaluronan (HA) may be beneficial for post-infa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e79e9fd29c60ce71535b33370ec41c1d
https://doi.org/10.1016/j.matbio.2022.08.008
https://doi.org/10.1016/j.matbio.2022.08.008
Autor:
Nadine Nagy, Gernot Kaber, Vivekananda G. Sunkari, Payton L. Marshall, Aviv Hargil, Hedwich F. Kuipers, Heather D. Ishak, Marika Bogdani, Rebecca L. Hull, Maria Grandoch, Jens W. Fischer, Tracey L. McLaughlin, Thomas N. Wight, Paul L. Bollyky
Publikováno v:
bioRxiv
Pancreatic β-cell dysfunction and death are central to the pathogenesis of type 2 diabetes (T2D). We have identified a novel role for the inflammatory extracellular matrix polymer hyaluronan (HA) in this pathophysiology. Low levels of HA are present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae04a1e25ff819bcbbe00d44dc1bdc6d
https://doi.org/10.1101/2023.02.28.530522
https://doi.org/10.1101/2023.02.28.530522
Autor:
Tatsiana Suvorava, Fedor Brack, Janet Kaczur, Patrick Petzsch, Karl Köhrer, Christine Quast, Nobert Gerdes, Katharina Voigt, Martina Krüger, Jens W. Fischer, Alexander Brückner, Bernd K. Fleischmann, Daniela Wenzel, Laura-Maria A. Zimmermann, Gerhard Sengle, Ulrich Flögel, Maria Grandoch
Abdominal aortic aneurysms (AAA) are a common vascular disorder with a high mortality due to the prevalence of aortic ruptures. The underlying pathomechanisms are complex and involve immune cell infiltration and degradation of the vascular extracellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97eb1a08b949a95b36eaa7cd09638d73
https://doi.org/10.1101/2022.12.01.518480
https://doi.org/10.1101/2022.12.01.518480
Autor:
Katherine Owsiany, Daniel J. Gorski, Gary K. Owens, Susanne Homann, Vlad Serbulea, Jens W. Fischer, Felicia Hartmann, Anne Petz, Rebecca A. Deaton, Michelle P. Bendeck, Alexandra A. C. Newman, Yu-Qing Zhou
Publikováno v:
Circ Res
Rationale: Plaque instability remains poorly understood and new therapeutic approaches to reduce plaque rupture and subsequent clinical events are of great interest. Recent studies revealed an important role of phenotypic switching of smooth muscle c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d90b8bad2298c054589a38683e3866
https://doi.org/10.1161/circresaha.120.318479
https://doi.org/10.1161/circresaha.120.318479
Autor:
Katharina Bottermann, Lisa Kalfhues, Rianne Nederlof, Anne Hemmers, Lucia M. Leitner, Vici Oenarto, Jana Nemmer, Mirjam Pfeffer, Vidisha Raje, Rene Deenen, Patrick Petzsch, Heba Zabri, Karl Köhrer, Andreas S. Reichert, Maria Grandoch, Jens W. Fischer, Diran Herebian, Johannes Stegbauer, Thurl E. Harris, Axel Gödecke
Publikováno v:
Basic Research in Cardiology. 117
Although p38 MAP Kinase α (p38 MAPKα) is generally accepted to play a central role in the cardiac stress response, to date its function in maladaptive cardiac hypertrophy is still not unambiguously defined. To induce a pathological type of cardiac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b696863849776bbc9071454166262f5
https://doi.org/10.1007/s00395-022-00955-2
https://doi.org/10.1007/s00395-022-00955-2