Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jens Verbeeren"'
Publikováno v:
PLoS Genetics, Vol 19, Iss 12, p e1011109 (2023)
The Muscleblind-like (MBNL) family is a highly conserved set of RNA-binding proteins (RBPs) that regulate RNA metabolism during the differentiation of various animal tissues. Functional insufficiency of MBNL affects muscle and central nervous system
Externí odkaz:
https://doaj.org/article/4c401e4164ff44d6870338bd7d352a6a
Autor:
Jens Verbeeren, Bhupendra Verma, Elina H Niemelä, Karen Yap, Eugene V Makeyev, Mikko J Frilander
Publikováno v:
PLoS Genetics, Vol 13, Iss 5, p e1006824 (2017)
Cellular homeostasis of the minor spliceosome is regulated by a negative feed-back loop that targets U11-48K and U11/U12-65K mRNAs encoding essential components of the U12-type intron-specific U11/U12 di-snRNP. This involves interaction of the U11 sn
Externí odkaz:
https://doaj.org/article/db1e852f794c46a88539e4da8f25ae15
Autor:
Ana R. S. Ribeiro, Ruslan I. Sadreyev, Olli Matilainen, Murat Cetinbas, Jens Verbeeren, Heini Sood, Susana M. D. A. Garcia
Publikováno v:
Genetics
Muscleblind-like splicing regulators (MBNLs) are RNA-binding factors that have an important role in developmental processes. Dysfunction of these factors is a key contributor of different neuromuscular degenerative disorders, including Myotonic Dystr
Autor:
Marijke P. Baltissen, Sandra Hanks, Eelco C. Tromer, Shawn Yost, Bas de Wolf, Geert J.P.L. Kops, Michiel Vermeulen, Philippe Piloquet, Bertrand Isidor, Ali Oghabian, Jolien J. E. van Hooff, Berend Snel, Esther C.H. Uijttewaal, Nazneen Rahman, Jens Verbeeren, Laura E van Rooijen, Lisa van Voorthuijsen, Maureen V. Akinyi, Mikko J. Frilander
Publikováno v:
EMBO Journal
EMBO Journal, 40(14), 1. Nature Publishing Group
EMBO Journal, 40(14). Nature Publishing Group
The EMBO Journal
EMBO Journal, 40(14), 1. Nature Publishing Group
EMBO Journal, 40(14). Nature Publishing Group
The EMBO Journal
Aneuploidy is the leading cause of miscarriage and congenital birth defects, and a hallmark of cancer. Despite this strong association with human disease, the genetic causes of aneuploidy remain largely unknown. Through exome sequencing of patients w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97d7b40146969ea51a965e5d52d5c292
https://dspace.library.uu.nl/handle/1874/414082
https://dspace.library.uu.nl/handle/1874/414082
Autor:
Jens Verbeeren, Ruslan I. Sadreyev, Murat Cetinbas, Susana M. D. A. Garcia, Ana R. S. Ribeiro, Olli Matilainen
Muscleblind-like splicing regulators (MBNLs) are alternative splicing factors that have an important role in developmental processes. Dysfunction of these factors is a key contributor of different neuromuscular degenerative disorders, including Myoto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc715891f3eacbce663f298a5365643e
https://doi.org/10.1101/2021.02.22.432374
https://doi.org/10.1101/2021.02.22.432374
Autor:
Karen Yap, Jens Verbeeren, Mikko J. Frilander, Elina H. Niemelä, Evgeniy V. Makeyev, Bhupendra Verma
Publikováno v:
Verbeeren, J, Verma, B, Niemelä, E H, Yap, K, Makeyev, E V & Frilander, M J 2017, ' Alternative exon definition events control the choice between nuclear retention and cytoplasmic export of U11/U12-65K mRNA ', PL o S Genetics, vol. 13, no. 5, e1006824 . https://doi.org/10.1371/journal.pgen.1006824
PLoS Genetics
PLoS Genetics, Vol 13, Iss 5, p e1006824 (2017)
PLoS Genetics
PLoS Genetics, Vol 13, Iss 5, p e1006824 (2017)
Cellular homeostasis of the minor spliceosome is regulated by a negative feed-back loop that targets U11-48K and U11/U12-65K mRNAs encoding essential components of the U12-type intron-specific U11/U12 di-snRNP. This involves interaction of the U11 sn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60b710068dc94d24890d32f6fab04183
http://hdl.handle.net/10138/199224
http://hdl.handle.net/10138/199224
Publikováno v:
RNA biology. 12(11)
Many splicing regulators bind to their own pre-mRNAs to induce alternative splicing that leads to formation of unstable mRNA isoforms. This provides an autoregulatory feedback mechanism that regulates the cellular homeostasis of these factors. We hav
Autor:
Mikko J. Frilander, Janne J. Turunen, Cindy L. Will, Reinhard Lührmann, Jens Verbeeren, Elina H. Niemelä, Janne J. Ravantti
Publikováno v:
Molecular Cell
Alternative pre-mRNA splicing is typically regulated by specific protein factors that recognize unique sequence elements in pre-mRNA and affect, directly or indirectly, nearby splice site usage. We show that 5' splice site sequences (5'ss) of U12-typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd0dc5410064249374b129af56fbf5ab
https://hdl.handle.net/11858/00-001M-0000-0012-D5F2-D11858/00-001M-0000-0028-1D39-911858/00-001M-0000-0028-1D37-D
https://hdl.handle.net/11858/00-001M-0000-0012-D5F2-D11858/00-001M-0000-0028-1D39-911858/00-001M-0000-0028-1D37-D
Publikováno v:
International journal of systematic and evolutionary microbiology. 55(Pt 4)
A group of 21 bacterial strains was isolated from samples of biofilm formation in the Servilia tomb (necropolis of Carmona, Spain) and the Saint-Catherine chapel (castle at Herberstein, Austria). A polyphasic taxonomic study of these isolates, includ
Publikováno v:
International journal of systematic and evolutionary microbiology. 54(Pt 5)
Three strains showing highly similar (GTG)5-PCR patterns were isolated from a heavily damaged mural painting at the Saint-Catherine chapel (Castle Herberstein, Austria). On the basis of 16S rRNA gene sequence similarity, the strains were attributed t