Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jens Velde, Andersen"'
Autor:
Theresa S. Rimmele, Shaomin Li, Jens Velde Andersen, Emil W. Westi, Alexander Rotenberg, Jianlin Wang, Blanca Irene Aldana, Dennis J. Selkoe, Chiye J. Aoki, Chris G. Dulla, Paul Allen Rosenberg
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
GLT-1, the major glutamate transporter in the mammalian central nervous system, is expressed in presynaptic terminals that use glutamate as a neurotransmitter, in addition to astrocytes. It is widely assumed that glutamate homeostasis is regulated pr
Externí odkaz:
https://doaj.org/article/bd922351081f490ab166d4b63a3be5b0
Autor:
Arne Schousboe, Jens Velde Andersen
Publikováno v:
Andersen, J V & Schousboe, A 2023, ' Milestone Review : Metabolic dynamics of glutamate and GABA mediated neurotransmission — The essential roles of astrocytes ', Journal of Neurochemistry, vol. 166, no. 2, pp. 109-137 . https://doi.org/10.1111/jnc.15811
Since it was first generally accepted that the two amino acids glutamate and GABA act as principal neurotransmitters, several landmark discoveries relating to this function have been uncovered. Synaptic homeostasis of these two transmitters involves
Autor:
Jens Velde Andersen, Jakob Dahl Nissen, Sofie Kjellerup Christensen, Kia Hjulmand Markussen, Helle Sønderby Waagepetersen
Publikováno v:
Neural Plasticity, Vol 2017 (2017)
Type 2 diabetes mellitus (T2DM) is a risk factor for the development of Alzheimer’s disease, and changes in brain energy metabolism have been suggested as a causative mechanism. The aim of this study was to investigate the cerebral metabolism of th
Externí odkaz:
https://doaj.org/article/f81ac53b50a447d89cbf1b877d7c5442
Autor:
Arne Schousboe, Jens Velde Andersen
Publikováno v:
Neurochemical research.
Glutamine is an essential cerebral metabolite. Several critical brain processes are directly linked to glutamine, including ammonia homeostasis, energy metabolism and neurotransmitter recycling. Astrocytes synthesize and release large quantities of g
Autor:
Maria Hvidberg Petersen, Cecilie Wennemoes Willert, Jens Velde Andersen, Mette Madsen, Helle Sønderby Waagepetersen, Niels Henning Skotte, Anne Nørremølle
Publikováno v:
Journal of Huntington's disease. 11(2)
Background: Huntington’s disease (HD) is a neurodegenerative disorder characterized by synaptic dysfunction and loss of white matter volume especially in the striatum of the basal ganglia and to a lesser extent in the cerebral cortex. Studies inves
Autor:
Anna Luna Mølgaard, Tams, Berta, Sanz-Morello, Emil Winther, Westi, Zaynab Ahmad, Mouhammad, Jens Velde, Andersen, Kristine Karla, Freude, Rupali, Vohra, Jens, Hannibal, Blanca Irene, Aldana, Miriam, Kolko
Publikováno v:
Acta Ophthalmologica. 100
Visual changes are some of the earliest symptoms that patients with Alzheimer's disease (AD) experience. Pathophysiological processes such as amyloid-β plaque formation, vascular changes, neuroinflammation, and loss of retinal ganglion cells (RGCs)
Autor:
Michael Sørensen, Anne Byriel Walls, Gitte Dam, Lasse Kristoffer Bak, Jens Velde Andersen, Peter Ott, Hendrik Vilstrup, Arne Schousboe
Publikováno v:
Sørensen, M, Walls, A B, Dam, G, Bak, L K, Andersen, J V, Ott, P, Vilstrup, H & Schousboe, A 2022, ' Low cerebral energy metabolism in hepatic encephalopathy reflects low neuronal energy demand. Role of ammonia-induced increased GABAergic tone ', Analytical Biochemistry, vol. 654, 114766 . https://doi.org/10.1016/j.ab.2022.114766
Hepatic encephalopathy (HE) is a frequent and devastating but generally reversible neuropsychiatric complication secondary to chronic and acute liver failure. During HE, brain energy metabolism is markedly reduced and it remains unclear whether this
Publikováno v:
Journal of Neurochemistry. 150:13-61
Publikováno v:
Journal of neuroscience research. 95(11)
Removal of endogenously released glutamate is mediated primarily by astrocytes and exogenous