Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Jens Uwe Marquardt"'
Autor:
Simon Johannes Gairing, Chiara Mangini, Lisa Zarantonello, Elise Jonasson, Henrike Dobbermann, Philippe Sultanik, Peter Robert Galle, Joachim Labenz, Dominique Thabut, Jens Uwe Marquardt, Patricia P. Bloom, Mette Munk Lauridsen, Sara Montagnese, Christian Labenz
Publikováno v:
JHEP Reports, Vol 6, Iss 8, Pp 101104- (2024)
Background & Aims: Data on the association between proton pump inhibitor (PPI) use and hepatic encephalopathy (HE) are conflicting, and data from multicentre studies are scarce. The aim of this study was to dissect the potential association between P
Externí odkaz:
https://doaj.org/article/0a4b191f35084e7bbef0e7add8959781
Autor:
Simon Johannes Gairing, Sven Danneberg, Leonard Kaps, Michael Nagel, Eva Maria Schleicher, Charlotte Quack, Sinah Engel, Stefan Bittner, Peter Robert Galle, Jörn Markus Schattenberg, Marcus-Alexander Wörns, Felix Luessi, Jens Uwe Marquardt, Christian Labenz
Publikováno v:
JHEP Reports, Vol 5, Iss 4, Pp 100671- (2023)
Background & Aims: Blood biomarkers facilitating the diagnosis of covert hepatic encephalopathy (CHE) in patients with cirrhosis are lacking. Astrocyte swelling is a major component of hepatic encephalopathy. Thus, we hypothesised that glial fibrilla
Externí odkaz:
https://doaj.org/article/701ec0faf173408db3245c6365e267e6
Autor:
Felix Thol, Simon Johannes Gairing, Carolin Czauderna, Thomas Thomaidis, Thomas Gamstätter, Yvonne Huber, Johanna Vollmar, Johanna Lorenz, Maurice Michel, Fabian Bartsch, Lukas Müller, Roman Kloeckner, Peter Robert Galle, Marcus-Alexander Wörns, Jens Uwe Marquardt, Markus Moehler, Arndt Weinmann, Friedrich Foerster
Publikováno v:
JHEP Reports, Vol 4, Iss 3, Pp 100417- (2022)
Background & Aims: Advanced biliary tract cancer (ABTC) is associated with a poor prognosis. Real-world data on the outcome of patients with ABTC undergoing sequential chemotherapies remain scarce, and little is known about treatment options beyond t
Externí odkaz:
https://doaj.org/article/ca54cc67fe5d403f87475984aa7900e7
Autor:
Svenja Meyhöfer, Armin Steffen, Kirstin Plötze-Martin, Christian Lange, Jens-Uwe Marquardt, Karl-Ludwig Bruchhage, Sebastian M. Meyhöfer, Ralph Pries
Publikováno v:
ImmunoHorizons. 7:191-199
Obesity is a dramatically increasing disease, accompanied with comorbidities such as cardiovascular disease and obstructive sleep apnea syndrome (OSAS). Both obesity and OSAS per se are associated with systemic inflammation. However, the multifactori
Publikováno v:
Gastroenterologie up2date. 18:369-388
Autor:
Hendrik Ungefroren, Axel Künstner, Hauke Busch, Sören Franzenburg, Kim Luley, Fabrice Viol, Jörg Schrader, Björn Konukiewitz, Ulrich F. Wellner, Sebastian M. Meyhöfer, Tobias Keck, Jens-Uwe Marquardt, Hendrik Lehnert
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 24; Pages: 15868
GEP-NETs are heterogeneous tumors originating from the pancreas (panNET) or the intestinal tract. Only a few patients with NETs are amenable to curative tumor resection, and for most patients, only palliative treatments to successfully control the di
Autor:
Hendrik Ungefroren, Rüdiger Braun, Olha Lapshyna, Björn Konukiewitz, Ulrich F. Wellner, Hendrik Lehnert, Jens-Uwe Marquardt
Publikováno v:
Biomedicines; Volume 10; Issue 10; Pages: 2640
Pancreatic ductal adenocarcinoma (PDAC) cells are known for their high invasive/metastatic potential, which is regulated in part by the transforming growth factor β1 (TGFβ1). The involvement of at least two type I receptors, ALK5 and ALK2, that tra
Autor:
Sophia Heinrich, Thomas Austgen, Darko Castven, Moritz Hess, Christian Labenz, Martha Kirstein, Carolin Zimpel, Lena Stockhoff, Benjamin Maasoumy, Bernd Heinrich, Hans Heinrich Wedemeyer, Peter Robert Galle, Harald Binder, Marc Nguyen‐Tat, Jens Uwe Marquardt
Publikováno v:
United European gastroenterology journalREFERENCES.
Hepatorenal syndrome is a major complication in patients with cirrhosis and associated with high mortality. Predictive biomarkers for therapy response are largely missing. Cytokeratin18-based cell death markers are significantly elevated in patients
Autor:
Simon Johannes Gairing, Robert Kuchen, Lukas Müller, Alper Cankaya, Jan Weerts, Akin Kapucu, Simon Sachse, Carolin Zimpel, Fabian Stoehr, Michael B. Pitton, Jens Mittler, Beate Katharina Straub, Jens Uwe Marquardt, Jörn M. Schattenberg, Christian Labenz, Roman Kloeckner, Arndt Weinmann, Peter Robert Galle, Marcus-Alexander Wörns, Friedrich Foerster
Publikováno v:
Clinical and translational gastroenterology. 13(10)
The 13 C-methacetin breath test ( 13 C-MBT) is a dynamic method for assessing liver function. This proof-of-concept study aimed to investigate the association between 13 C-MBT values and outcomes in patients with hepatocellular carcinoma (HCC) underg
Autor:
Hendrik Ungefroren, Isabel Thürling, Benedikt Färber, Tanja Kowalke, Tanja Fischer, Leonardo Vinícius Monteiro De Assis, Rüdiger Braun, Darko Castven, Henrik Oster, Björn Konukiewitz, Ulrich Friedrich Wellner, Hendrik Lehnert, Jens-Uwe Marquardt
Publikováno v:
Cancers; Volume 14; Issue 9; Pages: 2057
Intratumoral heterogeneity (ITH) is an intrinsic feature of malignant tumors that eventually allows a subfraction of resistant cancer cells to clonally evolve and cause therapy failure or relapse. ITH, cellular plasticity and tumor progression are dr