Zobrazeno 1 - 10
of 308
pro vyhledávání: '"Jens U. Marquardt"'
Autor:
Christian Schmithals, Bianca Kakoschky, Dominic Denk, Maike von Harten, Jan Henrik Klug, Edith Hintermann, Anne Dropmann, Eman Hamza, Anne Claire Jacomin, Jens U. Marquardt, Stefan Zeuzem, Peter Schirmacher, Eva Herrmann, Urs Christen, Thomas J. Vogl, Oliver Waidmann, Steven Dooley, Fabian Finkelmeier, Albrecht Piiper
Publikováno v:
EBioMedicine, Vol 105, Iss , Pp 105178- (2024)
Summary: Background: The accuracy of blood-based early tumour recognition is compromised by signal production at non-tumoral sites, low amount of signal produced by small tumours, and variable tumour production. Here we examined whether tumour-specif
Externí odkaz:
https://doaj.org/article/697990059c5e4e25a28e59b2e57c8d91
Autor:
Patrick S. Plum, Timo Hess, Denis Bertrand, Isabelle Morgenstern, Oscar Velazquez Camacho, Christoph Jonas, Christina Alidousty, Britta Wagner, Stephanie Roessler, Thomas Albrecht, Jessica Becker, Vanessa Richartz, Barbara Holz, Sascha Hoppe, Huay Mei Poh, Burton Kuan Hui Chia, Cheryl Xueli Chan, Thushangi Pathiraja, Audrey SM Teo, Jens U. Marquardt, Alexis Khng, Michael Heise, Yao Fei, René Thieme, Sebastian Klein, Jing Han Hong, Simona O Dima, Irinel Popescu, Maria Hoppe‐Lotichius, Reinhard Buettner, Anja Lautem, Gerd Otto, Alexander Quaas, Niranjan Nagarajan, Steve Rozen, Bin Tean Teh, Benjamin Goeppert, Uta Drebber, Hauke Lang, Patrick Tan, Ines Gockel, Johannes Schumacher, Axel M. Hillmer
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 6, Pp n/a-n/a (2024)
Abstract Background Cholangiocarcinoma (CCA) is a fatal cancer of the bile duct with a poor prognosis owing to limited therapeutic options. The incidence of intrahepatic CCA (iCCA) is increasing worldwide, and its molecular basis is emerging. Environ
Externí odkaz:
https://doaj.org/article/26260a111e4f40929c73d9cf914a4148
Autor:
Tanja Fererberger, Christa Buechler, Arne Kandulski, Tanja Elger, Johanna Loibl, Stephan Schmid, Stefanie Sommersberger, Stefan Gunawan, Sebastian Zundler, Muriel Huss, Dominik Bettenworth, Sally Kempa, Simon Weidlich, Bandik Föh, Xinyu Huang, Marcin Grzegorzek, Stefanie Derer-Petersen, Ulrich L. Günther, Jens U. Marquardt, Claudia Kunst, Karsten Gülow, Martina Müller, Christian Sina, Franziska Schmelter, Hauke C. Tews
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
IntoductionIdentification of specific metabolome and lipidome profile of patients with primary sclerosing cholangitis (PSC) is crucial for diagnosis, targeted personalized therapy, and more accurate risk stratification.MethodsNuclear magnetic resonan
Externí odkaz:
https://doaj.org/article/09253d97ee434a928fe26eb14955b0ba
Autor:
Ralph Pries, Friederike Katharina Kosyna, Reinhard Depping, Kirstin Plötze-Martin, Christian Lange, Svenja Meyhöfer, Sebastian M. Meyhöfer, Jens U. Marquardt, Karl-Ludwig Bruchhage, Armin Steffen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Obstructive sleep apnea syndrome (OSAS) and obesity go hand in hand in the majority of patients and both are associated with a systemic inflammation, immune disturbance and comorbidities such as cardiovascular disease. However, the unambiguo
Externí odkaz:
https://doaj.org/article/5c75873caf3443b7b43d7ce4361ba42b
Autor:
Amanda J. Craig, Maruhen A. Datsch Silveira, Lichun Ma, Mahler Revsine, Limin Wang, Sophia Heinrich, Zachary Rae, Allison Ruchinskas, Kimia Dadkhah, Whitney Do, Shay Behrens, Farid R. Mehrabadi, Dana A. Dominguez, Marshonna Forgues, Anuradha Budhu, Jittiporn Chaisaingmongkol, Jonathan M. Hernandez, Jeremy L. Davis, Bao Tran, Jens U. Marquardt, Mathuros Ruchirawat, Michael Kelly, Tim F. Greten, Xin W. Wang
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113446- (2023)
Summary: Primary liver cancer (PLC) consists of two main histological subtypes; hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (iCCA). The role of transcription factors (TFs) in malignant hepatobiliary lineage commitment between H
Externí odkaz:
https://doaj.org/article/c7e7f7a06b594b8cba26dbb54618423b
Autor:
Lichun Ma, Sophia Heinrich, Limin Wang, Friederike L. Keggenhoff, Subreen Khatib, Marshonna Forgues, Michael Kelly, Stephen M. Hewitt, Areeba Saif, Jonathan M. Hernandez, Donna Mabry, Roman Kloeckner, Tim F. Greten, Jittiporn Chaisaingmongkol, Mathuros Ruchirawat, Jens U. Marquardt, Xin Wei Wang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Multiregion sequencing is needed to better capture the heterogeneity of hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (iCCA). Here, the authors analyse HCC and iCCA tumours with multiregion single-cell RNA-seq, revealing cellular
Externí odkaz:
https://doaj.org/article/f2ebde2426ee4ec09a8cd16dac1ffe6f
Autor:
Kaan Yilmaz, Onur Dikmen, Nina van Beek, Jens U. Marquardt, Martha M. Kirstein, Detlef Zillikens, Enno Schmidt
Publikováno v:
Acta Dermato-Venereologica, Vol 103 (2023)
Mucous membrane pemphigoid is an autoimmune blistering disorder characterized by predominant involvement of surface-close epithelia and linear depositions of immunoreactants at the dermal-epithelial junction on direct immunofluorescence microscopy. A
Externí odkaz:
https://doaj.org/article/31eaa54bd36a4a9badfd6435007fd666
Autor:
Darko Castven, Carolin Czauderna, Diana Becker, Sharon Pereira, Jennifer Schmitt, Arndt Weinmann, Viral Shah, Jovana Hajduk, Friederike Keggenhoff, Harald Binder, Tobias Keck, Stefanie Heilmann‐Heimbach, Marcus A. Wörns, Snorri S. Thorgeirsson, Kai Breuhahn, Peter R. Galle, Jens U. Marquardt
Publikováno v:
Hepatology Communications, Vol 6, Iss 5, Pp 1140-1156 (2022)
Induction of neoangiogenesis is a hallmark feature during disease progression of hepatocellular carcinoma (HCC). Antiangiogenetic compounds represent a mainstay of therapeutic approaches; however, development of chemoresistance is observed in the maj
Externí odkaz:
https://doaj.org/article/cede644f770a4897acbb1b8893fbe1cc
Autor:
Hamish Innes, Hans Dieter Nischalke, Indra Neil Guha, Karl Heinz Weiss, Will Irving, Daniel Gotthardt, Eleanor Barnes, Janett Fischer, M. Azim Ansari, Jonas Rosendahl, Shang‐Kuan Lin, Astrid Marot, Vincent Pedergnana, Markus Casper, Jennifer Benselin, Frank Lammert, John McLauchlan, Philip L. Lutz, Victoria Hamill, Sebastian Mueller, Joanne R. Morling, Georg Semmler, Florian Eyer, Johann von Felden, Alexander Link, Arndt Vogel, Jens U. Marquardt, Stefan Sulk, Jonel Trebicka, Luca Valenti, Christian Datz, Thomas Reiberger, Clemens Schafmayer, Thomas Berg, Pierre Deltenre, Jochen Hampe, Felix Stickel, Stephan Buch
Publikováno v:
Hepatology Communications, Vol 6, Iss 5, Pp 1213-1226 (2022)
The host genetic background for hepatocellular carcinoma (HCC) is incompletely understood. We aimed to determine if four germline genetic polymorphisms, rs429358 in apolipoprotein E (APOE), rs2642438 in mitochondrial amidoxime reducing component 1 (M
Externí odkaz:
https://doaj.org/article/b9ad89289a29441c95f20c3bfffcbd53
Autor:
Michael Nagel, Vanessa Weidner, Sina Schulz, Jens U. Marquardt, Peter R. Galle, Jörn M. Schattenberg, Marc Nguyen-Tat, Marcus-Alexander Wörns, Christian Labenz
Publikováno v:
Health and Quality of Life Outcomes, Vol 20, Iss 1, Pp 1-8 (2022)
Abstract Background Patients with liver cirrhosis suffer from significantly reduced health-related quality of life and are often dependent on support from caregivers. In this context, caregivers often suffer from impaired quality of life (QoL) as wel
Externí odkaz:
https://doaj.org/article/ccaf1e535aaf4611a0470ba4691a0d29