Zobrazeno 1 - 10
of 268
pro vyhledávání: '"Jens Schmidt"'
Autor:
Hannah Wilcke, Stefanie Glaubitz, Fabian Kück, Christoph Anten, David Liebetanz, Jens Schmidt, Jana Zschüntzsch
Publikováno v:
BMC Neurology, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background Myasthenia gravis (MG) affects individuals as a chronic autoimmune disease for many years. Commonly, chronic diseases significantly reduce the patients’ quality of life. Aiming to improve the future quality of life in MG, this s
Externí odkaz:
https://doaj.org/article/2f2005e009144adaa5554bab7c79d3ab
Autor:
Jens Schmidt
Publikováno v:
Project Leadership and Society, Vol 4, Iss , Pp 100097- (2023)
This paper shows how causes and mechanisms behind past information technology (IT) project failures can be used for systematic risk mitigation in new IT projects. This is significant because successful IT projects are needed to realise the benefit po
Externí odkaz:
https://doaj.org/article/70350fb2e8a042fa91d733e56c616b2b
Autor:
Per-Ole Carstens, Luisa M. Müllar, Arne Wrede, Sabrina Zechel, Martin M. Wachowski, Almuth Brandis, Sabine Krause, Stephan Zierz, Jens Schmidt
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionWe aimed to identify B-cell-mediated immunomechanisms in inclusion body myositis (IBM) and polymyositis (PM) as part of the complex pathophysiology.Materials and methodsHuman primary myotube cultures were derived from orthopedic surgery.
Externí odkaz:
https://doaj.org/article/23060bdf8e2743068f853639ee4aa7c1
Autor:
Marc Pawlitzki, Laura Acar, Lars Masanneck, Alice Willison, Liesa Regner-Nelke, Christopher Nelke, Helmut L’hoest, Ursula Marschall, Jens Schmidt, Sven G. Meuth, Tobias Ruck
Publikováno v:
Neurological Research and Practice, Vol 4, Iss 1, Pp 1-11 (2022)
Abstract Background The medical care of patients with myositis is a great challenge in clinical practice. This is due to the rarity of these disease, the complexity of diagnosis and management as well as the lack of systematic analyses. Objectives Th
Externí odkaz:
https://doaj.org/article/d35dd452430440b08d7dcc282b5fb5e0
Autor:
Mina Shahriyari, Md Rezaul Islam, Sadman M. Sakib, Malte Rinn, Anastasia Rika, Dennis Krüger, Lalit Kaurani, Verena Gisa, Mandy Winterhoff, Harithaa Anandakumar, Orr Shomroni, Matthias Schmidt, Gabriela Salinas, Andreas Unger, Wolfgang A. Linke, Jana Zschüntzsch, Jens Schmidt, Rhonda Bassel‐Duby, Eric N. Olson, André Fischer, Wolfram‐Hubertus Zimmermann, Malte Tiburcy
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 6, Pp 3106-3121 (2022)
Abstract Background Human pluripotent stem cell‐derived muscle models show great potential for translational research. Here, we describe developmentally inspired methods for the derivation of skeletal muscle cells and their utility in skeletal musc
Externí odkaz:
https://doaj.org/article/1634c6c809c344e3adcd3f61bb3b0fea
Publikováno v:
EPJ Techniques and Instrumentation, Vol 8, Iss 1, Pp 1-19 (2021)
Abstract Electric space propulsion thrusters only produce low thrust forces. For the fulfillment of a space mission this implies long thruster runtimes, and this entails long qualification times on ground. For such long testing times, a ground facili
Externí odkaz:
https://doaj.org/article/ae0e0e52c21c4dcfa967bf5ec9e6dd37
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10675 (2023)
Inclusion body myositis (IBM) is a chronic, mostly treatment-resistant, inflammatory myopathy with a pathology that centers around specific interactions between inflammation and protein accumulation. The study aimed to identify the inflammasome as a
Externí odkaz:
https://doaj.org/article/4ccace0af427443986a6d9d246c8f3a0
Autor:
Stefanie Meyer, Silke Kaulfuß, Sabrina Zechel, Karsten Kummer, Ali Seif Amir Hosseini, Marielle Sophie Ernst, Jens Schmidt, Silke Pauli, Jana Zschüntzsch
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
BackgroundBenefits and challenges resulting from advances in genetic diagnostics are two sides of the same coin. Facilitation of a correct and timely diagnosis is paralleled by challenges in interpretation of variants of unknown significance (VUS). F
Externí odkaz:
https://doaj.org/article/d364b67d3d9e4ada90453d0c8f88eebb
Autor:
Gloria I. Perez, David Broadbent, Ahmed A. Zarea, Benedikt Dolgikh, Matthew P. Bernard, Alicia Withrow, Amelia McGill, Victoria Toomajian, Lukose K. Thampy, Jack Harkema, Joel R. Walker, Thomas A. Kirkland, Michael H. Bachmann, Jens Schmidt, Masamitsu Kanada
Publikováno v:
Advanced Genetics, Vol 3, Iss 1, Pp n/a-n/a (2022)
Abstract Cancer cells produce heterogeneous extracellular vesicles (EVs) as mediators of intercellular communication. This study focuses on a novel method to image EV subtypes and their biodistribution in vivo. A red‐shifted bioluminescence resonan
Externí odkaz:
https://doaj.org/article/815d5e51afbb41bdac0ccb970b00d3f4
Autor:
Jana Zschüntzsch, Pia Vanessa Jouvenal, Yaxin Zhang, Florian Klinker, Malte Tiburcy, David Liebetanz, Dörthe Malzahn, Heinrich Brinkmeier, Jens Schmidt
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 4, Pp 1018-1031 (2020)
Abstract Background Duchenne muscular dystrophy (DMD) is a progressive muscle‐wasting disease caused by mutations in the dystrophin gene, which leads to structural instability of the dystrophin–glycoprotein‐complex with subsequent muscle degene
Externí odkaz:
https://doaj.org/article/9a90a27f2bd24e59bf059097ed604059