Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Jens S. Andersen"'
Autor:
Jens S. Andersen, Aaran Vijayakumaran, Christopher Godbehere, Esben Lorentzen, Vito Mennella, Kenneth Bødtker Schou
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Centrosomes and cilia are microtubule-based superstructures vital for cell division, signaling, and motility. The once thought hollow lumen of their microtubule core structures was recently found to hold a rich meshwork of microtubule inner
Externí odkaz:
https://doaj.org/article/3844c72b2b4c460dbdffd91d1c8604c6
Autor:
Patrik Polák, William Garland, Om Rathore, Manfred Schmid, Anna Salerno-Kochan, Lis Jakobsen, Maria Gockert, Piotr Gerlach, Toomas Silla, Jens S. Andersen, Elena Conti, Torben Heick Jensen
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113325- (2023)
Summary: The RNA exosome is a versatile ribonuclease. In the nucleoplasm of mammalian cells, it is assisted by its adaptors the nuclear exosome targeting (NEXT) complex and the poly(A) exosome targeting (PAXT) connection. Via its association with the
Externí odkaz:
https://doaj.org/article/011a771c02a44db48dc70d320227324d
Autor:
Marta Montes, Michal Lubas, Frederic S. Arendrup, Bettina Mentz, Neha Rohatgi, Sarunas Tumas, Lea M. Harder, Anders J. Skanderup, Jens S. Andersen, Anders H. Lund
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Senescence-associated secretory phenotype (SASP) involves secretion of factors such as pro-inflammatory cytokines. Here the authors show that MIR31HG regulates the expression and secretion of a subset of SASP components that induce paracrine invasion
Externí odkaz:
https://doaj.org/article/8da6f54bfa9d4666b2534cafaba5a56a
Autor:
Sanne Løkkegaard, Daniel Elias, Carla L. Alves, Martin V. Bennetzen, Anne-Vibeke Lænkholm, Martin Bak, Morten F. Gjerstorff, Lene E. Johansen, Henriette Vever, Christina Bjerre, Tove Kirkegaard, Bo Nordenskjöld, Tommy Fornander, Olle Stål, Linda S. Lindström, Laura J. Esserman, Anne E. Lykkesfeldt, Jens S. Andersen, Rikke Leth-Larsen, Henrik J. Ditzel
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-15 (2021)
Abstract Resistance to endocrine therapy in estrogen receptor-positive (ER+) breast cancer is a major clinical problem with poorly understood mechanisms. There is an unmet need for prognostic and predictive biomarkers to allow appropriate therapeutic
Externí odkaz:
https://doaj.org/article/c7b5ad6a5a674cfcb8ece9f12b5c68d6
Autor:
Søs Grønbæk Holdgaard, Valentina Cianfanelli, Emanuela Pupo, Matteo Lambrughi, Michal Lubas, Julie C. Nielsen, Susana Eibes, Emiliano Maiani, Lea M. Harder, Nicole Wesch, Mads Møller Foged, Kenji Maeda, Francesca Nazio, Laura R. de la Ballina, Volker Dötsch, Andreas Brech, Lisa B. Frankel, Marja Jäättelä, Franco Locatelli, Marin Barisic, Jens S. Andersen, Simon Bekker-Jensen, Anders H. Lund, Vladimir V. Rogov, Elena Papaleo, Letizia Lanzetti, Daniela De Zio, Francesco Cecconi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Centrosomes drive mitotic spindle formation and chromosome segregation. Here, the authors show that centrosome stability is regulated by selective autophagic degradation of centriolar satellite components in a process they term doryphagy, connecting
Externí odkaz:
https://doaj.org/article/332640b7f2f048bebeba04c9ee651443
Autor:
Maren Mönnich, Louise Borgeskov, Loretta Breslin, Lis Jakobsen, Michaela Rogowski, Canan Doganli, Jacob M. Schrøder, Johanne B. Mogensen, Louise Blinkenkjær, Lea M. Harder, Emma Lundberg, Stefan Geimer, Søren T. Christensen, Jens S. Andersen, Lars A. Larsen, Lotte B. Pedersen
Publikováno v:
Cell Reports, Vol 22, Iss 10, Pp 2584-2592 (2018)
Summary: The centrosome is the main microtubule-organizing center in animal cells and comprises a mother and daughter centriole surrounded by pericentriolar material. During formation of primary cilia, the mother centriole transforms into a basal bod
Externí odkaz:
https://doaj.org/article/a68234e28fda4bce9920a039ecebb8ef
Autor:
Kinga Winczura, Manfred Schmid, Claudia Iasillo, Kelly R. Molloy, Lea Mørch Harder, Jens S. Andersen, John LaCava, Torben Heick Jensen
Publikováno v:
Cell Reports, Vol 22, Iss 1, Pp 44-58 (2018)
Summary: Nuclear RNA metabolism is influenced by protein complexes connecting to both RNA-productive and -destructive pathways. The ZC3H18 protein binds the cap-binding complex (CBC), universally present on capped RNAs, while also associating with th
Externí odkaz:
https://doaj.org/article/fa492696d2bd437c9e4a322a379dbb08
Autor:
Simone Giacometti, Nour El Houda Benbahouche, Michal Domanski, Marie-Cécile Robert, Nicola Meola, Michal Lubas, Jakob Bukenborg, Jens S. Andersen, Wiebke M. Schulze, Celine Verheggen, Grzegorz Kudla, Torben Heick Jensen, Edouard Bertrand
Publikováno v:
Cell Reports, Vol 18, Iss 11, Pp 2635-2650 (2017)
The nuclear cap-binding complex (CBC) stimulates processing reactions of capped RNAs, including their splicing, 3′-end formation, degradation, and transport. CBC effects are particular for individual RNA families, but how such selectivity is achiev
Externí odkaz:
https://doaj.org/article/173fd29c006e48f3b1da6b440058ecb1
Autor:
Jens S. Andersen, Juri Rappsilber, Hanno Steen, Akhilesh Pandey, Henrik Molina, Michael Lund, Alexandre Podtelejnikov, Angus I. Lamond, Matthias Mann
Publikováno v:
The Scientific World Journal, Vol 2, Pp 91-92 (2002)
Externí odkaz:
https://doaj.org/article/7e26cce6fb224741b5af9ab0c0513e57
Autor:
Marcus E. Peter, Christopher B. Burge, Jinbo Xu, Christine Feig, Jens S. Andersen, Jeppe Vinther, Mads M. Hedegaard, Noam Shomron, Sun-Mi Park, Benjamin Boyerinas
Supplementary Table 2 from Identification of Let-7–Regulated Oncofetal Genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::328fa2a94d0cfd33442670cbf490a72f
https://doi.org/10.1158/0008-5472.22377269
https://doi.org/10.1158/0008-5472.22377269