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pro vyhledávání: '"Jens S Kalchschmidt"'
Autor:
Jens S Kalchschmidt, Adam C T Gillman, Kostas Paschos, Quentin Bazot, Bettina Kempkes, Martin J Allday
Publikováno v:
PLoS Pathogens, Vol 12, Iss 1, p e1005383 (2016)
It is well established that Epstein-Barr virus nuclear antigen 3C (EBNA3C) can act as a potent repressor of gene expression, but little is known about the sequence of events occurring during the repression process. To explore further the role of EBNA
Externí odkaz:
https://doaj.org/article/e8f97bf739ab4b8fb015b4ca2ffdc8f3
Autor:
Quentin Bazot, Kostas Paschos, Lenka Skalska, Jens S Kalchschmidt, Gillian A Parker, Martin J Allday
Publikováno v:
PLoS Pathogens, Vol 11, Iss 7, p e1005031 (2015)
We show that two host-encoded primary RNAs (pri-miRs) and the corresponding microRNA (miR) clusters--widely reported to have cell transformation-associated activity--are regulated by EBNA3A and EBNA3C. Utilising a variety of EBV-transformed lymphobla
Externí odkaz:
https://doaj.org/article/5df2e90ec487485f89827bb3463b05d7
Autor:
Adam C. T. Gillman, Rachael Bashford-Rogers, Martin J. Allday, Christine T. Styles, Paul Kellam, Jens S. Kalchschmidt, Kostas Paschos
Publikováno v:
The Journal of Experimental Medicine
Allday and collaborators demonstrate that the EBV transcription factor and oncoprotein EBNA3C directly induces the expression of AID and somatic mutations in B cells, providing a mechanism linking infection and lymphoma induction.
Activation-ind
Activation-ind
Autor:
Adam C. T. Gillman, Jens S. Kalchschmidt, Quentin Bazot, Kostas Paschos, Bettina Kempkes, Martin J. Allday
Publikováno v:
PLoS Pathogens, Vol 12, Iss 1, p e1005383 (2016)
PLoS Pathogens
PLoS Pathog. 12:e1005383 (2016)
PLoS Pathogens
PLoS Pathog. 12:e1005383 (2016)
It is well established that Epstein-Barr virus nuclear antigen 3C (EBNA3C) can act as a potent repressor of gene expression, but little is known about the sequence of events occurring during the repression process. To explore further the role of EBNA