Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jens Roedig"'
Autor:
Lisa Kowald, Jens Roedig, Rebekka Karlowitz, Kristina Wagner, Sonja Smith, Thomas Juretschke, Petra Beli, Stefan Müller, Sjoerd J. L. van Wijk
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Ubiquitin-specific peptidase 22 (USP22) is a deubiquitinating enzyme (DUB) that underlies tumorigenicity, proliferation, cell death and differentiation through deubiquitination of histone and non-histone targets. Ubiquitination determines st
Externí odkaz:
https://doaj.org/article/0fc6c043461f4dadbb7ba5930e2dcbc7
Autor:
Nadine Weinelt, Kaja Nicole Wächtershäuser, Gulustan Celik, Birte Jeiler, Isabelle Gollin, Laura Zein, Sonja Smith, Geoffroy Andrieux, Tonmoy Das, Jens Roedig, Leonard Feist, Björn Rotter, Melanie Boerries, Francesco Pampaloni, Sjoerd J. L. van Wijk
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Plasma membrane accumulation of phosphorylated mixed lineage kinase domain-like (MLKL) is a hallmark of necroptosis, leading to membrane rupture and inflammatory cell death. Pro-death functions of MLKL are tightly controlled by several check
Externí odkaz:
https://doaj.org/article/e14e541c4820493ea444b18cd9044345
Autor:
Rebekka Karlowitz, Megan L. Stanifer, Jens Roedig, Geoffroy Andrieux, Denisa Bojkova, Marco Bechtel, Sonja Smith, Lisa Kowald, Ralf Schubert, Melanie Boerries, Jindrich Cinatl, Steeve Boulant, Sjoerd J. L. van Wijk
Publikováno v:
Cell Death and Disease, Vol 13, Iss 8, Pp 1-14 (2022)
Abstract Pattern recognition receptors (PRRs) and interferons (IFNs) serve as essential antiviral defense against SARS-CoV-2, the causative agent of the COVID-19 pandemic. Type III IFNs (IFN-λ) exhibit cell-type specific and long-lasting functions i
Externí odkaz:
https://doaj.org/article/e0cff6daeb78475a8d5002c6e431347e
Autor:
Annkathrin Koch, Birte Jeiler, Jens Roedig, Sjoerd J.L. van Wijk, Nadezda Dolgikh, Simone Fulda
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 5, Pp 539-550 (2021)
Burkitt's lymphoma (BL) is a highly aggressive form of B-cell non-Hodgkin's lymphoma. The clinical outcome in children with BL has improved over the last years but the prognosis for adults is still poor, highlighting the need for novel treatment stra
Externí odkaz:
https://doaj.org/article/746d29e524ac4212a6dfac6ce63571a4
Autor:
Barbara Knapp, Jens Roedig, Heiko Roedig, Jacek Krzysko, Nicola Horn, Baran E. Güler, Deva Krupakar Kusuluri, Adem Yildirim, Karsten Boldt, Marius Ueffing, Ines Liebscher, Uwe Wolfrum
Publikováno v:
Molecules, Vol 27, Iss 10, p 3108 (2022)
The very large G-protein-coupled receptor 1 (VLGR1/ADGRV1) is the largest member of the adhesion G-protein-coupled receptor (ADGR) family. Mutations in VLGR1/ADGRV1 cause human Usher syndrome (USH), a form of hereditary deaf-blindness, and have been
Externí odkaz:
https://doaj.org/article/67b286e6cb1d44d49dd2470a446591ba
Autor:
Nadine Weinelt, Kaja Nicole Wächtershäuser, Sonja Smith, Geoffroy Andrieux, Tonmoy Das, Birte Jeiler, Jens Roedig, Leonard Feist, Björn Rotter, Melanie Boerries, Francesco Pampaloni, Sjoerd J. L. van Wijk
SummaryPlasma membrane accumulation of phosphorylated mixed lineage kinase domain-like (MLKL) is a hallmark of necroptosis, leading to membrane rupture and inflammatory cell death. Pro-death functions of MLKL are tightly controlled by several checkpo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4828c0934cdfab986bcf7f630ce0d9c1
https://doi.org/10.1101/2022.12.08.519265
https://doi.org/10.1101/2022.12.08.519265
Autor:
Sjoerd J L van Wijk, Simone Fulda, Birte Jeiler, Jens Roedig, Nadezda Dolgikh, Annkathrin Koch
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 5, Pp 539-550 (2021)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 5, Pp 539-550 (2021)
Burkitt's lymphoma (BL) is a highly aggressive form of B-cell non-Hodgkin's lymphoma. The clinical outcome in children with BL has improved over the last years but the prognosis for adults is still poor, highlighting the need for novel treatment stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e65da807d73e5d104985297a80089959
https://pubmed.ncbi.nlm.nih.gov/33971465
https://pubmed.ncbi.nlm.nih.gov/33971465
Autor:
Petra Beli, Lisa Kowald, Jens Roedig, Rebekka Karlowitz, Behnaz Ahangarian Abhari, Sjoerd J L van Wijk, Heiko Roedig, Simone Fulda, Thomas Juretschke
Publikováno v:
EMBO Reports
Dynamic control of ubiquitination by deubiquitinating enzymes is essential for almost all biological processes. Ubiquitin‐specific peptidase 22 (USP22) is part of the SAGA complex and catalyzes the removal of mono‐ubiquitination from histones H2A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::927194889b2a225d1caa6921089bce1b
http://europepmc.org/articles/PMC7857539
http://europepmc.org/articles/PMC7857539
Autor:
Uwe Wolfrum, Jacek Krzysko, Karsten Boldt, Jens Roedig, Nicola Horn, Marius Ueffing, Barbara Knapp
Publikováno v:
Annals of the New York Academy of SciencesReferences. 1456(1)
Adhesion G protein-coupled receptors (ADGRs) have recently become a target of intense research. Their unique protein structure, which consists of a G protein-coupled receptor combined with long adhesive extracellular domains, suggests a dual role in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::000bb8bfc614db426982eb947a78c1ca
https://pubmed.ncbi.nlm.nih.gov/31441075
https://pubmed.ncbi.nlm.nih.gov/31441075