Corrigendum: Guidance for the treatment of adult growth hormone deficiency with somapacitan, a long-acting growth hormone preparation

Autor: Martin Bidlingmaier, Beverly M.K. Biller, David Clemmons, Jens Otto L. Jørgensen, Hiroshi Nishioka, Yutaka Takahashi

Publikováno v: Frontiers in Endocrinology, Vol 14 (2023)

Externí odkaz: https://doaj.org/article/7671dc9111c045bfb0254559001ea363

Investigating effects of sodium beta‐hydroxybutyrate on metabolism in placebo‐controlled, bilaterally infused human leg with focus on skeletal muscle protein dynamics

Autor: Henrik Holm Thomsen, Jonas Franck Olesen, Rasmus Aagaard, Bent Roni Ranghøj Nielsen, Thomas Schmidt Voss, Mads Vandsted Svart, Mogens Johannsen, Niels Jessen, Jens Otto L. Jørgensen, Nikolaj Rittig, Ermina Bach, Niels Møller

Publikováno v: Physiological Reports, Vol 10, Iss 16, Pp n/a-n/a (2022)

Abstract Systemic administration of beta‐hydroxybutyrate (BHB) decreases whole‐body protein oxidation and muscle protein breakdown in humans. We aimed to determine any direct effect of BHB on skeletal muscle protein turnover when administered loc

Externí odkaz: https://doaj.org/article/8132f763b5bd45d786d79ddae11579b7

Gene expression profiling of subcutaneous adipose tissue reveals new biomarkers in acromegaly

Autor: Camilla M Falch, Mai Christiansen Arlien-Søborg, Jakob Dal, Arvind Y M Sundaram, Annika E Michelsen, Thor Ueland, Linn Guro Olsen, Ansgar Heck, Jens Bollerslev, Jens Otto L Jørgensen, Nicoleta C Olarescu

Publikováno v: Falch, C M, Arlien-Søborg, M C, Dal, J, Sundaram, A Y M, Michelsen, A E, Ueland, T, Olsen, L G, Heck, A, Bollerslev, J, Jørgensen, J O L & Olarescu, N C 2023, ' Gene expression profiling of subcutaneous adipose tissue reveals new biomarkers in acromegaly ', European Journal of Endocrinology, vol. 188, no. 3, pp. 310-321 . https://doi.org/10.1093/ejendo/lvad031
Falch, C M, Arlien-Søborg, M C, Dal, J, Sundaram, A Y M, Michelsen, A E, Ueland, T, Olsen, L G, Heck, A, Bollerslev, J, Jørgensen, J O L & Olarescu, N C 2023, ' Gene expression profiling of subcutaneous adipose tissue reveals new biomarkers in acromegaly ', European Journal of Endocrinology, vol. 188, no. 3, pp. 310–321 . https://doi.org/10.1093/ejendo/lvad031

Context: Active acromegaly is characterized by lipolysis-induced insulin resistance, which suggests adipose tissue (AT) as a primary driver of metabolic aberrations.Objective: To study the gene expression landscape in AT in patients with acromegaly b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93237f05c499c89a6d9e7e6b9678ecfe
https://doi.org/10.1093/ejendo/lvad031

Insulin Resistance in Patients With Acromegaly

Autor: Greisa Vila, Jens Otto L. Jørgensen, Anton Luger, Günter K. Stalla

Publikováno v: Frontiers in Endocrinology, Vol 10 (2019)

Acromegaly is characterized by chronic overproduction of growth hormone (GH) that leads to insulin resistance, glucose intolerance and, ultimately, diabetes. The GH-induced sustained stimulation of lipolysis plays a major role not only in the develop

Externí odkaz: https://doaj.org/article/3d26b21f9bac4998a8b153d127bcd842

Evaluation of functional erythropoietin receptor status in skeletal muscle in vivo: acute and prolonged studies in healthy human subjects.

Autor: Britt Christensen, Carsten Lundby, Niels Jessen, Thomas S Nielsen, Poul F Vestergaard, Niels Møller, Henriette Pilegaard, Steen B Pedersen, John J Kopchick, Jens Otto L Jørgensen

Publikováno v: PLoS ONE, Vol 7, Iss 2, p e31857 (2012)

BackgroundErythropoietin receptors have been identified in human skeletal muscle tissue, but downstream signal transduction has not been investigated. We therefore studied in vivo effects of systemic erythropoietin exposure in human skeletal muscle.M

Externí odkaz: https://doaj.org/article/beb3bcdc00064017b631103d3a01a457