Zobrazeno 1 - 10 of 51 pro vyhledávání: '"Jens Ole Nielsen"'
1
CIRCULATING T AND B LYMPHOCYTES AND IMMUNOGLOBULIN CONTAINING CELLS IN THE LIVER IN CHRONIC ACTIVE LIVER DISEASE
Autor: J Aldershvile, Jens Ole Nielsen, Finn Hardt, Odd Dietrichson
Publikováno v: Acta Pathologica Microbiologica Scandinavica Section C Immunology. :26-32
The number of circulating T and B lymphocytes was estimated in 25 patients with biopsy-verified chronic non alcoholic liver disease. Fifteen of these had circulating HBSAg and/or anti-HBSAg and 10 were without these markers of HB virus infection. In
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe8080ed2cd41269c225f4649620e73
https://doi.org/10.1111/j.1699-0463.1977.tb03607.x
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2
The Acquired Immunodeficiency Syndrome (AIDS) in Denmark
Autor: E. Dickmeiss, J. Gerstoft, P. Platz, T. Rønne, Lars Mathiesen, Jens Ole Nielsen
Publikováno v: Acta Medica Scandinavica. 217:213-224
Twenty Danish patients with the acquired immunodeficiency syndrome (AIDS) had been diagnosed by January 1984, 14 of them after 1982. Eighteen patients were male homosexuals, 8 of whom had visited the USA after 1979, 2 were heterosexual males with a h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a4c4eacfb401b5732f9bb484ca14a24b
https://doi.org/10.1111/j.0954-6820.1985.tb01658.x
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3
Tenofovir treatment in an unselected cohort of highly antiretroviral experienced HIV positive patients
Autor: Jan Gerstoft, Alex Lund Laursen, Klaus Larsen, Lars Mathiesen, Jens Ole Nielsen, Terese L. Katzenstein, Niels Obel, Claus J. Nielsen, Anne Lerbæk, Thomas Birk Kristiansen, Susanne Dam Nielsen
Publikováno v: Lerbæk, A, Kristiansen, T B, Katzenstein, T L, Mathiesen, L, Gerstoft, J, Nielsen, C, Larsen, K, Nielsen, J O, Obel, N, Laursen, A L & Nielsen, S D 2004, ' Tenofovir treatment in an unselected cohort of highly antiretroviral experienced HIV positive patients ', Scandinavian Journal of Infectious Diseases, vol. 36, no. 4, pp. 280-286 . https://doi.org/10.1080/00365540410019633
The aim of the present study was to explore the treatment effect of tenofovir as implemented in clinical practice. Data are presented on 34 patients. 11 patients had tenofovir added to a stable anti-retroviral treatment (ART) and 23 patients had drug
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042c551655e7719bef954d9b3a3eb1bc
https://doi.org/10.1080/00365540410019633
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4
Treatment with Granulocyte Colony–Stimulating Factor Decreases the Capacity of Hematopoietic Progenitor Cells for Generation of Lymphocytes in Human Immunodeficiency Virus–Infected Persons
Autor: Sjoerd Repping, Susanne Dam Nielsen, Marianne Hutchings, Lars Mathiesen, John-Erik Stig Hansen, Jens Ole Nielsen, Dawn R. Clark, Sanne Dam-Larsen, Frank Miedema
Publikováno v: Journal of infectious diseases, 180(6), 1819-1826. Oxford University Press
An obstacle to stem cell gene therapy for AIDS is the limited numbers of hematopoietic progenitors available. Granulocyte colony-stimulating factor (G-CSF) is used for mobilization of progenitors, but little is known about the functional characterist
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::074589ef9a5023ffaf12d23886f5f012
https://doi.org/10.1086/315136
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5
Transduction potential of human retroviruses in highly proliferating small-cell lung cancer cells as well as non-proliferating hematopoietic stem cells
Autor: Susanne Dam Nielsen, Gregers J. Gram, Maxwell Sehested, Peter Buhl Jensen, John-Erik Stig Hansen, Jens Ole Nielsen, Anders Sørensen, Mikael Rørth
Publikováno v: Europe PubMed Central
Direct gene transfer to solid tissues or metastatic cancer cells requires vectors capable of in vivo transduction to specific cells. The predominant retroviral vectors of murine origin are inactivated by human complement, which precludes their use in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dab584f3aca69b0298878ea05b995aa
https://doi.org/10.1111/j.1699-0463.1997.tb05077.x
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6
Complement-Mediated Enhancement of HIV-1 Infection in Peripheral Blood Mononuclear Cells
Autor: Susanne Dam Nielsen, Anne Marie Møller Sørensen, Ole Søgaard Lund, John-Erik Stig Hansen, Jens Ole Nielsen, Kristian Schønning
Publikováno v: Scandinavian Journal of Infectious Diseases. 29:447-452
We investigated if complement-mediated enhancement of HIV infection occurs in peripheral blood mononuclear cells (PBMC). In 7 experiments, we evaluated the effect of human complement on HIVIIIB infection in vitro. We measured HIV antigen production o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18ac974a43bc99c21cd3544200da4893
https://doi.org/10.3109/00365549709011852
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7
Resistance to V3-Directed Neutralization Caused by an N-Linked Oligosaccharide Depends on the Quaternary Structure of the HIV-1 Envelope Oligomer
Autor: John-Erik Stig Hansen, Sigvard Olofsson, Britt Jansson, Kristian Schønning, Jens Ole Nielsen
Publikováno v: Virology. 218(1):134-140
A conserved N-glycan present within the V3 loop of gp120 modulates the sensitivity to neutralization by antibodies directed to the V3 loop. A glycan-deficient mutant of HIV LAI , designated HIV A308 , displayed a 100-fold increase in sensitivity to n
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8
Sensitivity of HIV-1 to neutralization by antibodies against O-linked carbohydrate epitopes despite deletion of O-glycosylation signals in the V3 loop
Autor: Henrik Clausen, Gregers J. Gram, John-Erik Stig Hansen, Jens Ole Nielsen, Sigvard Olofsson, Britt Jansson
Publikováno v: Archives of Virology. 141:291-300
It has been suggested that threonine or serine residues in the V3 loop of HIV-1 gp120 are glycosylated with the short-chain O-linked oligosaccharides Tn or sialosyl-Tn that function as epitopes for broadly neutralizing carbohydrate specific antibodie
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c615a5ab4e4d16d561ba8672368544e4
https://doi.org/10.1007/bf01718400
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9
Inhibition of HIV-1 in vitro by C-5 propyne phosphorothioate antisense to rev
Autor: Jens Ole Nielsen, Ole Søgaard Lund, John-Erik Stig Hansen
Publikováno v: Antiviral Research. 28:81-91
A 15-mer C-5 propyne modified phosphorothioate oligodeoxynucleotide antisense to rev was approximately 5-fold more effective in providing viral inhibition compared to a 28-mer unmodified phosphorothioate oligodeoxynucleotide targeted to the same sequ
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db64093310578b9327d3caa62fd571e
https://doi.org/10.1016/0166-3542(95)00041-j
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10
Six billion neurons lost in AIDS
Autor: Jens Ole Nielsen, Court Pedersen, Solveig Oster, H. J. G. Gundersen, Rente Pakkenberg, Per Christoffersen
Publikováno v: APMIS. 103:525-529
Human immunodeficiency virus type 1 (HIV1) is neurotropic. One of the morphological changes that is seen in patients with acquired immunodeficiency syndrome (AIDS) is cerebral atrophy affecting various structures including the neocortex. The cause of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::82f7d191f06c77f0cab24affc51b9a55
https://doi.org/10.1111/j.1699-0463.1995.tb01401.x
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