Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jens Modrof"'
Publikováno v:
Emerging Infectious Diseases, Vol 15, Iss 10, Pp 1668-1670 (2009)
This study investigated the association of ongoing West Nile virus (WNV) infections with neutralizing antibody titers in US plasma-derived intravenous immune globulin released during 2003–2008. Titers correlated closely with the prevalence of past
Externí odkaz:
https://doaj.org/article/17d4e070105c4c5e82f075378c87646f
Medical progress as enabled by early plasma products has also revealed biological safety challenges. The combination of donor selection, donation testing and virus reduction processes has effectively addressed these concerns, and today medicinal plas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b49dd7d088b036b7948ca18ab52c3a0
https://doi.org/10.22541/au.168063855.51303786/v1
https://doi.org/10.22541/au.168063855.51303786/v1
Autor:
Paul W. Barone, Flora J. Keumurian, Caleb Neufeld, Andrea Koenigsberg, Robert Kiss, James Leung, Michael Wiebe, Rima Ait-Belkacem, Chakameh Azimpour Tabrizi, Cristina Barbirato, Pascale Beurdeley, Audrey Brussel, Jean-Pol Cassart, Colette Cote, Noémie Deneyer, Veera Dheenadhayalan, Leyla Diaz, Angela Geiselhoeringer, Maria M. Gilleece, Jakob Goldmann, Danielle Hickman, Angela Holden, Björn Keiner, Martina Kopp, Thomas R. Kreil, Christophe Lambert, Carine Logvinoff, Brandye Michaels, Jens Modrof, Brian Mullan, Jürgen Mullberg, Marie Murphy, Sean O'Donnell, José Peña, Michael Ruffing, Horst Ruppach, Nasrin Salehi, Shahjahan Shaid, Lindsey Silva, Richard Snyder, Mélancolie Spedito-Jovial, Olivier Vandeputte, Bernice Westrek, Bin Yang, Ping Yang, Stacy L. Springs
Publikováno v:
Biologicals : journal of the International Association of Biological Standardization.
The Consortium on Adventitious Agent Contamination in Biomanufacturing (CAACB) collected historical data from 20 biopharmaceutical industry members on their experience with the in vivo adventitious virus test, the in vitro virus test, and the use of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18fdade44cfe97b4941436ee939b7239
https://pubmed.ncbi.nlm.nih.gov/36621353
https://pubmed.ncbi.nlm.nih.gov/36621353
Autor:
Daniela Niemeyer, Victor M. Corman, Maria R. Farcet, Thomas Kreil, Jens Modrof, Astrid Kerschbaum
Publikováno v:
Biologicals
With the pandemic emergence of SARS-CoV-2, the exposure of cell substrates used for manufacturing of medicines has become a possibility. Cell lines used in biomanufacturing were thus evaluated for their SARS-CoV-2 susceptibility, and the detection of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eac66b29795fff85445bda11f865bc15
https://doi.org/10.22541/au.159121409.99363381
https://doi.org/10.22541/au.159121409.99363381
Autor:
Sandra M. Leydold, Simone Knotzer, Thomas R. Kreil, Michael Karbiener, Jens Modrof, Johanna Kindermann
Publikováno v:
Biologicals : journal of the International Association of Biological Standardization. 64
Virus contamination events in cell culture-based biotechnology processes have occurred and have had a dramatic impact on the supply of life-saving drugs, and thus on the wellbeing of patients. Cleanup requires effective and robust virucidal decontami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7449682cddd0b85b3a49530699a18a7
https://pubmed.ncbi.nlm.nih.gov/32057565
https://pubmed.ncbi.nlm.nih.gov/32057565
Autor:
Philip D. Minor, Thomas R. Kreil, Philip O. Rabel, Jens Modrof, Helen Fox, Andrew J. Macadam, Maria R. Farcet, Andreas Schirmer
Publikováno v:
Transfusion. 58
Background Wild-type poliovirus may be eradicated soon and under WHO GAPIII guidance, laboratory use will be discontinued or subject to strict containment. Per US Code of Federal Regulations, however, immunoglobulin lot release testing will still req
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3914e62a3941f41987624b71efe5ad1b
https://pubmed.ncbi.nlm.nih.gov/30536436
https://pubmed.ncbi.nlm.nih.gov/30536436
Autor:
Jens Modrof, Philip O. Rabel, Andreas Wieser, Andreas Flicker, Ulrike Unger, Thomas R. Kreil, Cornelia Lackner, Maria R. Farcet, Gerhard Antoine
Publikováno v:
Transfusion. 56:383-391
BACKGROUND Hepatitis E virus (HEV) has been transmitted by transfusion of labile blood products and the occasional detection of HEV RNA in plasma pools indicates that HEV viremic donations might enter the manufacturing process of plasma products. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::384ac44204f553b8895af135ac7b2486
https://doi.org/10.1111/trf.13343
https://doi.org/10.1111/trf.13343
Publikováno v:
Biologicals
The efficacy of gaseous disinfection is critical for prevention and treatment of microbial contamination in biotechnological facilities. For an evaluation of gaseous disinfection efficacy, a down-scaled laboratory model was established, using current
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed707661559290bdefe3411051a5d97f
http://europepmc.org/articles/PMC7129659
http://europepmc.org/articles/PMC7129659
Autor:
Peter Fitzgerald, Thomas R. Kreil, Jessica A Schreiner, Maria R. Farcet, John McVey, Jens Modrof, Toby L Simon, Maria Gudino, Charles M Borders, Björn Tille
Publikováno v:
The Journal of infectious diseases. 216(8)
We report a screen of plasma donors confirming that widespread use of childhood measles vaccination since 1963 resulted in a decrease in average measles virus antibody titers among plasma donors, which is reflected in intravenous immunoglobulins (IVI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::729c6f3b9367424195f6bcf9754d3bd3
https://pubmed.ncbi.nlm.nih.gov/28968738
https://pubmed.ncbi.nlm.nih.gov/28968738
Autor:
Sandra M. Leydold, Gerhard Pölsler, Andreas Berting, Johanna Kindermann, P. Noel Barrett, Maria R. Farcet, M. Keith Howard, Thomas R. Kreil, Jens Modrof
Publikováno v:
Transfusion. 52:2122-2130
BACKGROUND: Chikungunya virus (CHIKV) outbreaks were previously restricted to parts of Africa, Indian Ocean Islands, South Asia, and Southeast Asia. In 2007, however, the first autochthonous CHIKV transmission was reported in Europe. High-level virem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efd9f9cba51740328100aa860e831e1e
https://doi.org/10.1111/j.1537-2995.2012.03565.x
https://doi.org/10.1111/j.1537-2995.2012.03565.x