Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jens Michael Seeger"'
ATP synthase modulation leads to an increase of spare respiratory capacity in HPV associated cancers
Autor:
Matthias Kirschberg, Sandra Heuser, Gian Paolo Marcuzzi, Martin Hufbauer, Jens Michael Seeger, Anamaria Đukić, Vjekoslav Tomaić, Slawomir Majewski, Steffen Wagner, Claus Wittekindt, Nora Würdemann, Jens Peter Klussmann, Alexander Quaas, Hamid Kashkar, Baki Akgül
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Mucosal and skin cancers are associated with infections by human papillomaviruses (HPV). The manner how viral oncoproteins hijack the host cell metabolism to meet their own energy demands and how this may contribute to tumorigenesis is poorl
Externí odkaz:
https://doaj.org/article/11881e22fa564878ac276b326468d4d4
Autor:
Kerstin Brinkmann, Paola Zigrino, Axel Witt, Michael Schell, Leena Ackermann, Pia Broxtermann, Stephan Schüll, Maria Andree, Oliver Coutelle, Benjamin Yazdanpanah, Jens Michael Seeger, Daniela Klubertz, Uta Drebber, Ulrich T. Hacker, Martin Krönke, Cornelia Mauch, Thorsten Hoppe, Hamid Kashkar
Publikováno v:
Cell Reports, Vol 3, Iss 3, Pp 881-891 (2013)
The BH3-only protein NOXA represents one of the critical mediators of DNA-damage-induced cell death. In particular, its involvement in cellular responses to cancer chemotherapy is increasingly evident. Here, we identify a strategy of cancer cells to
Externí odkaz:
https://doaj.org/article/fa941ddbd6ea4fb9a312631c8f1e6f2e
Autor:
Hamid Kashkar, Martin Krönke, Hinrich Abken, Cornelia Mauch, Diana Wagner-Stippich, Paola Zigrino, Oliver Coutelle, Andreas A. Hombach, Kerstin Brinkmann, Patrick Schmidt, Jens Michael Seeger
Supplementary Figures 1-3 from The Proteasome Inhibitor Bortezomib Sensitizes Melanoma Cells toward Adoptive CTL Attack
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4623e42f22350ba883f91383b83ef520
https://doi.org/10.1158/0008-5472.22386929.v1
https://doi.org/10.1158/0008-5472.22386929.v1
Autor:
Mila Daoud, Pia Nora Broxtermann, Fabian Schorn, J Paul Werthenbach, Jens Michael Seeger, Lars M Schiffmann, Kerstin Brinkmann, Domagoj Vucic, Thomas Tüting, Cornelia Mauch, Dagmar Kulms, Paola Zigrino, Hamid Kashkar
Publikováno v:
EMBO reports. 23(6)
Elevated expression of the X-linked inhibitor of apoptosis protein (XIAP) has been frequently reported in malignant melanoma suggesting that XIAP renders apoptosis resistance and thereby supports melanoma progression. Independent of its anti-apoptoti
Autor:
Martin Krönke, Anke Deggerich, Carola Pongratz, Dirk Haubert, Katja Wiegmann, Hamid Kashkar, Jens-Michael Seeger, Benjamin Yazdanpanah
Publikováno v:
Blood. 109(9)
The proteasome inhibitor bortezomib has been shown to possess promising antitumor activity and significant efficacy against a variety of malignancies. Different studies demonstrated that bortezomib breaks the chemoresistance in different tumor cells
Autor:
Hinrich Abken, Gerd Heimlich, Anke Deggerich, Benjamin Yazdanpanah, Jens Michael Seeger, Hamid Kashkar, M Krönke, Andreas Hombach, Olaf Utermohlen
Publikováno v:
Blood. 108(10)
The immunosurveillance of Hodgkin lymphoma (HL) by cytotoxic T lymphocytes (CTLs) is insufficient, and the clinical experience with adoptive transfer of CTLs is limited. We have previously reported that defects in mitochondrial apoptotic pathways and