Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Jens M. Schröder"'
Autor:
Soumitra Mohanty, Witchuda Kamolvit, Andrea Scheffschick, Anneli Björklund, Jonas Tovi, Alexander Espinosa, Kerstin Brismar, Thomas Nyström, Jens M. Schröder, Claes-Göran Östenson, Pontus Aspenström, Hanna Brauner, Annelie Brauner
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Patients with diabetes have an increased susceptibility to infections. Here the authors show that high glucose impairs innate immunity through reduced levels of the antimicrobial peptide psoriasin and impaired epithelial barrier function, resulting i
Externí odkaz:
https://doaj.org/article/ea03a48fa5854868a7989405e31a4087
Autor:
Nanna Fyhrquist, Gareth Muirhead, Stefanie Prast-Nielsen, Marine Jeanmougin, Peter Olah, Tiina Skoog, Gerome Jules-Clement, Micha Feld, Mauricio Barrientos-Somarribas, Hanna Sinkko, Ellen H. van den Bogaard, Patrick L.J.M. Zeeuwen, Gijs Rikken, Joost Schalkwijk, Hanna Niehues, Walter Däubener, Silvia Kathrin Eller, Helen Alexander, Davide Pennino, Sari Suomela, Ioannis Tessas, Emilia Lybeck, Anna M. Baran, Hamid Darban, Roopesh Singh Gangwar, Ulrich Gerstel, Katharina Jahn, Piia Karisola, Lee Yan, Britta Hansmann, Shintaro Katayama, Stephan Meller, Max Bylesjö, Philippe Hupé, Francesca Levi-Schaffer, Dario Greco, Annamari Ranki, Jens M. Schröder, Jonathan Barker, Juha Kere, Sophia Tsoka, Antti Lauerma, Vassili Soumelis, Frank O. Nestle, Bernhard Homey, Björn Andersson, Harri Alenius
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Atopic dermatitis (AD) and psoriasis (PSO) are associated with dysbiosis. Here, by analyses of skin microbiome and host transcriptome of AD and PSO patients, the authors find distinct microbial and disease-related gene transcriptomic signatures that
Externí odkaz:
https://doaj.org/article/801d353e9aec45f68391d2416fdff3f4
Autor:
Björn Andersson, Jens M. Schröder, Annamari Ranki, Melissa Saichi, Sophia Tsoka, Péter Oláh, Stefanie Prast-Nielsen, Mauricio Barrientos-Somarribas, Noora Ottman, Lukas Wisgrill, Bernhard Homey, Frank O. Nestle, Nanna Fyhrquist, Alain Lefèvre‐Utile, Juha Kere, Philippe Hupé, Dario Greco, Marc Delord, Jonathan Baker, Antti Lauerma, Francesca Levi-Schaffer, Harri Alenius, Vassili Soumelis, Helen Alexander
Publikováno v:
Allergy. 77:1486-1498
BACKGROUND Atopic dermatitis (AD) is a frequent and heterogeneous inflammatory skin disease, for which personalized medicine remains a challenge. High-throughput approaches have improved understanding of the complex pathophysiology of AD. However, a
Autor:
Peter Oláh, Eszter Szlávicz, Marcus Kuchner, Jana Nemmer, Patrick Zeeuwen, Alain Lefèvre-Utile, Nanna Fyhrquist, Stefanie Prast-Nielsen, Tiina Skoog, Angela Serra, Elke Rodríguez, Ulrike Raap, Stephan Meller, Rolland Gyulai, Philippe Hupé, Juha Kere, Francesca Levi-Schaffer, Sophia Tsoka, Helen Alexander, Frank O. Nestle, Jens M. Schröder, Stephan Weidinger, Ellen van den Bogaard, Vassili Soumelis, Dario Greco, Jonathan Barker, Antti Lauerma, Annamari Ranki, Björn Andersson, Harri Alenius, Bernhard Homey
Publikováno v:
Journal of Dermatological Science, 106, 3, pp. 132-140
Journal of Dermatological Science, 106, 132-140
Journal of Dermatological Science, 106, 132-140
Contains fulltext : 251811.pdf (Publisher’s version ) (Closed access) BACKGROUND: Loss-of-function mutations in the filaggrin (FLG) gene directly alter skin barrier function and critically influence atopic inflammation. While skin barrier dysfuncti
Autor:
Soumitra Mohanty, Witchuda Kamolvit, Andrea Scheffschick, Anneli Björklund, Jonas Tovi, Alexander Espinosa, Kerstin Brismar, Thomas Nyström, Jens M. Schröder, Claes-Göran Östenson, Pontus Aspenström, Hanna Brauner, Annelie Brauner
Publikováno v:
Nature communications. 13(1)
Diabetes is known to increase susceptibility to infections, partly due to impaired granulocyte function and changes in the innate immunity. Here, we investigate the effect of diabetes, and high glucose on the expression of the antimicrobial peptide,
Autor:
Annamari Ranki, Péter Oláh, Lukas Wisgrill, Antti Lauerma, Jonathan Barker, Björn Andersson, Helen Alexander, Francesca Levi-Schaffer, Mauricio Barrientos-Somarribas, Harri Alenius, Vassili Soumelis, Frank O. Nestle, Noora Ottman, Sophia Tsoka, Jens M. Schröder, Juha Kere, Nanna Fyhrquist, Dario Greco, Bernhard Homey
Publikováno v:
Allergy
It is well established that different sites in healthy human skin are colonized by distinct microbial communities due to different physiological conditions. However, few studies have explored microbial heterogeneity between skin sites in diseased ski
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c8a09af17217e8b99ba6e20b9f53cc6
https://trepo.tuni.fi/handle/10024/127989
https://trepo.tuni.fi/handle/10024/127989
Autor:
Ellen H. van den Bogaard, Jens M. Schröder, Sophia Tsoka, Marine Jeanmougin, Lee Yan, Hamid Darban, Björn Andersson, Gijs Rikken, Davide Pennino, Shintaro Katayama, Piia Karisola, Ulrich Gerstel, Katharina Jahn, Vassili Soumelis, Hanna Niehues, Philippe Hupé, Britta Hansmann, Joost Schalkwijk, Anna M. Baran, Roopesh Singh Gangwar, Stefanie Prast-Nielsen, Dario Greco, Sari Suomela, Annamari Ranki, Walter Däubener, Frank O. Nestle, Péter Oláh, Helen Alexander, Tiina Skoog, Patrick L.J.M. Zeeuwen, Gerome Jules-Clement, Max Bylesjö, Micha Feld, Bernhard Homey, Emilia Lybeck, Antti Lauerma, Jonathan Barker, Gareth Muirhead, Ioannis Tessas, Silvia Kathrin Eller, Stephan Meller, Nanna Fyhrquist, Mauricio Barrientos-Somarribas, Juha Kere, Francesca Levi-Schaffer, Hanna Sinkko, Harri Alenius
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications
Nature Communications, 10, 4703
Nature Communications, 10, 1, pp. 4703
Fyhrquist, N, Muirhead, G S, Prast-Nielsen, S, Jeanmougin, M, Olah, P, Skoog, T, Jules-Clement, G, Feld, M, Barrientos-Somarribas, M, Sinkko, H, van den Bogaard, E H, Zeeuwen, P L J M, Rikken, G, Schalkwijk, J, Niehues, N, Däubener, W, Eller, S K, Alexander, H, Pennino, D, Suomela, S, Tessas, I, Lybeck, E, Baran, A M, Darban, H, Roopesh Singh, G, Gerstel, U, Jahn, K, Karisola, P, Yan, L, Hansmann, B, Katayama, S, Meller, S, Bylesjö, M, Hupé, P, Levi-Schaffer, F, Greco, D, Ranki, A, Schröder, J M, Barker, J N W N, Kere, J, Tsoka, S, Lauerma, A, Soumelis, V, Nestle, F O, Homey, B, Andersson, B & Alenius, H 2019, ' Microbe-host interplay in atopic dermatitis and psoriasis ', Nature Communications, vol. 10, no. 1, 4703 . https://doi.org/10.1038/s41467-019-12253-y
Nature Communications
Nature Communications, 10, 4703
Nature Communications, 10, 1, pp. 4703
Fyhrquist, N, Muirhead, G S, Prast-Nielsen, S, Jeanmougin, M, Olah, P, Skoog, T, Jules-Clement, G, Feld, M, Barrientos-Somarribas, M, Sinkko, H, van den Bogaard, E H, Zeeuwen, P L J M, Rikken, G, Schalkwijk, J, Niehues, N, Däubener, W, Eller, S K, Alexander, H, Pennino, D, Suomela, S, Tessas, I, Lybeck, E, Baran, A M, Darban, H, Roopesh Singh, G, Gerstel, U, Jahn, K, Karisola, P, Yan, L, Hansmann, B, Katayama, S, Meller, S, Bylesjö, M, Hupé, P, Levi-Schaffer, F, Greco, D, Ranki, A, Schröder, J M, Barker, J N W N, Kere, J, Tsoka, S, Lauerma, A, Soumelis, V, Nestle, F O, Homey, B, Andersson, B & Alenius, H 2019, ' Microbe-host interplay in atopic dermatitis and psoriasis ', Nature Communications, vol. 10, no. 1, 4703 . https://doi.org/10.1038/s41467-019-12253-y
Despite recent advances in understanding microbial diversity in skin homeostasis, the relevance of microbial dysbiosis in inflammatory disease is poorly understood. Here we perform a comparative analysis of skin microbial communities coupled to globa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6610272fc0b03d655041f17877f5b05
http://hdl.handle.net/10138/306834
http://hdl.handle.net/10138/306834
Publikováno v:
Autoimmunity in Psoriasis ISBN: 9780429280283
Polymorphonuclear leukocytes (PMNs) are highly motile mammalian cells, which tend to migrate to the sites of tissue injury or inflammation. In psoriasis the presence of large numbers of PMNs within the diseased epidermis is well recognized and has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f68ee109ff8a974e6964e443d65cd3e8
https://doi.org/10.1201/9780429280283-9
https://doi.org/10.1201/9780429280283-9
Autor:
Jens-M. Schröder
Publikováno v:
Cell Host Microbe
Vitamin A deficiency increases susceptibility to skin infection. However, the mechanisms by which vitamin A regulates skin immunity remain unclear. Here, we show that resistin-like molecule α (RELMα), a small secreted cysteine-rich protein, is expr
Autor:
Curdin Conrad, Sophie Durr, Dipyaman Ganguly, Roberto Lande, Michel Gilliet, Olivier Demaria, Georgios Chamilos, Loredana Frasca, Jens M. Schröder
Publikováno v:
European Journal of Immunology. 45:203-213
Psoriasis is a T-cell-mediated skin autoimmune disease characterized by the aberrant activation of dermal dendritic cells (DCs) and the sustained epidermal expression of antimicrobial peptides. We have previously identified a link between these two e