Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jens Loncke"'
Autor:
Mailis Liiv, Annika Vaarmann, Dzhamilja Safiulina, Vinay Choubey, Ruby Gupta, Malle Kuum, Lucia Janickova, Zuzana Hodurova, Michal Cagalinec, Akbar Zeb, Miriam A. Hickey, Yi-Long Huang, Nana Gogichaishvili, Merle Mandel, Mario Plaas, Eero Vasar, Jens Loncke, Tim Vervliet, Ting-Fen Tsai, Geert Bultynck, Vladimir Veksler, Allen Kaasik
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Wolfram syndrome is a rare genetic disease caused by mutations in the WFS1 or CISD2 gene. A primary defect in Wolfram syndrome involves poor ER Ca2+ handling, but how this disturbance leads to the disease is not known. The current study, per
Externí odkaz:
https://doaj.org/article/7119060b6c6844ed9cd995417943a2ed
Publikováno v:
BBA Advances, Vol 4, Iss , Pp 100105- (2023)
INPP5K (inositol polyphosphate 5-phosphatase K) is an endoplasmic reticulum (ER)-resident enzyme that acts as a phosphoinositide (PI) 5-phosphatase, capable of dephosphorylating various PIs including PI 4,5-bisphosphate (PI(4,5)P2), a key phosphoinos
Externí odkaz:
https://doaj.org/article/e39116bb13b34679bdd8ad09b7fdb31d
Publikováno v:
EBioMedicine, Vol 74, Iss , Pp 103741- (2021)
Externí odkaz:
https://doaj.org/article/85b4fd60bcf647bca7d5dcdd5d519b22
Publikováno v:
Cells, Vol 11, Iss 12, p 1963 (2022)
Calcium ions (Ca2+) operate as important messengers in the cell, indispensable for signaling the underlying numerous cellular processes in all of the cell types in the human body. In neurons, Ca2+ signaling is crucial for regulating synaptic transmis
Externí odkaz:
https://doaj.org/article/0b8e26c3068345129b7455cac6897599
Calcium ions (Ca2+) operate as important messengers in the cell, indispensable for signaling the underlying numerous cellular processes in all of the cell types in the human body. In neurons, Ca2+ signaling is crucial for regulating synaptic transmis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::571d1daea8671bc92687aa5b525a07ca
https://lirias.kuleuven.be/handle/20.500.12942/697908
https://lirias.kuleuven.be/handle/20.500.12942/697908
Publikováno v:
Cells. 11(12)
Calcium ions (Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d31a4cf3df3cc65564d06fdcb2b8ba07
https://pubmed.ncbi.nlm.nih.gov/35741091
https://pubmed.ncbi.nlm.nih.gov/35741091
Publikováno v:
Current Opinion in Physiology. 17:80-88
IP3 receptors (IP3Rs) are intracellular Ca2+ release channels gated by IP3 that are located in the endoplasmic reticulum (ER), including subregions that are in close contact with other organelles such as mitochondria. Recent studies have discovered u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff7b2f571ba54b5fe3b7c84ba9e3c1ac
https://doi.org/10.1016/j.cophys.2020.07.011
https://doi.org/10.1016/j.cophys.2020.07.011
Publikováno v:
Science signaling. 14(702)
Mutations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::05139f7e152383cb7e1ca4dda6905cd7
https://pubmed.ncbi.nlm.nih.gov/34582248
https://pubmed.ncbi.nlm.nih.gov/34582248
Publikováno v:
Science Signaling. 14
Mutations in WFS1 (which encodes Wolframin, WFS1) and CISD2 (which encodes CDGSH iron sulfur domain 2) result in Wolfram syndrome (WS), a rare genetic disorder that starts with juvenile diabetes an...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::faeef387c41f67062d9571c58bab8772
https://doi.org/10.1126/scisignal.abc6165
https://doi.org/10.1126/scisignal.abc6165
Publikováno v:
Trends Cell Biol
Organelles cooperate with each other to control cellular homeostasis and cell functions by forming close connections through membrane contact sites. Important contacts are present between the endoplasmic reticulum (ER), the main intracellular Ca2+-st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7840741cc855f828668b2b45dd61e5de
https://europepmc.org/articles/PMC8195822/
https://europepmc.org/articles/PMC8195822/