Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jens Leike"'
Publikováno v:
Investigative Radiology. 36:303-308
RATIONALE AND OBJECTIVES Contrast-carrying liposomes are potentially useful as computed tomography (CT) blood-pool agents. In the present study, preliminary safety, pharmacokinetics, and the CT imaging behavior of continuously extruded iopromide-carr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe541b9636f3bd9bbf2ff34668a78903
https://doi.org/10.1097/00004424-200106000-00001
https://doi.org/10.1097/00004424-200106000-00001
Publikováno v:
Academic Radiology. 6:164-169
Rationale and Objectives. The purpose of this study was to determine the feasibility of using iodinated liposomes as blood pool agents for computed tomography (CT) in nonhuman primates. Materials and Methods. Five normal adult baboons (15–21 kg) we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8852765099a8508a79dfd36a7282d320
https://doi.org/10.1016/s1076-6332(99)80402-4
https://doi.org/10.1016/s1076-6332(99)80402-4
Autor:
Jens Leike, T. Schneider, G. Röβling, Martin Brandl, Margret Schmidtgen, Andreas Sachse, Markus Drechsler
Publikováno v:
International Journal of Pharmaceutics. 132:9-21
Surface-modified, contrast-carrying liposomes were generated by incorporation of amphipathic polymers into the membranes of continuously extruded vesicles. Besides the well described distearoylphosphatidylethanolamine monomethoxypolyethyleneglycol (D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::179639600ce95ace650a0bca7dbda6ac
https://doi.org/10.1016/0378-5173(95)04247-4
https://doi.org/10.1016/0378-5173(95)04247-4
Publikováno v:
Journal of Liposome Research. 6:665-680
Biodistribution and computed tomography (CT) imaging characteristics of iopromide-carrying liposomes were investigated in healthy or tumor-bearing rats. The mean diameter of the liposomes obtained by the ethanol evaporation method was approximately 0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54a9aa65fda81b549733ce665d317beb
https://doi.org/10.3109/08982109609039920
https://doi.org/10.3109/08982109609039920
Publikováno v:
Academic Radiology. 2:967-972
Rationale and Objectives. We studied the feasibility of using iodinated liposomes as computed tomography (CT) liver contrast agents in nonhuman primates. Methods. Iopromide-containing liposomes were investigated as reticuloendothelial (RES) contrast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dc42bc19ead083d1e1d14aa5b442554
https://doi.org/10.1016/s1076-6332(05)80697-x
https://doi.org/10.1016/s1076-6332(05)80697-x
Publikováno v:
Journal of Liposome Research. 5:933-953
Rationale and Objectives:The use of contrast-carrying liposomes in diagnostic applications (1) or of haemoglobin liposomes in blood replacement therapy (2) requires infusion of large lipid doses. Saturated lipids like HSPC are often used in these for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eebf1258fdc55c48f2b2b96d57fb7a78
https://doi.org/10.3109/08982109509012691
https://doi.org/10.3109/08982109509012691
Publikováno v:
Pharmaceutical Research. 12:1065-1071
Purpose. The dose-proportionality of pharmacokinetics of an iodinated contrast medium, iopromide, encapsulated into liposomes was investigated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a377b02a12906e551c28d6fe3b9a365a
https://doi.org/10.1023/a:1016226918768
https://doi.org/10.1023/a:1016226918768
Publikováno v:
Journal of Liposome Research. 4:239-253
Iopromide-carrying liposomes were prepared by the ethanol evaporation method and pharmacokinetic parameters and CT imaging efficiency were determined in rats and rabbits. The mean diameter of the liposomes was 0.5±0.1 urn and the encapsulation effic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7596b4a07e2710a03f3765572a2aabea
https://doi.org/10.3109/08982109409037040
https://doi.org/10.3109/08982109409037040
Publikováno v:
Investigative Radiology. 28:1028-1032
RATIONALE AND OBJECTIVES Iopromide-carrying liposomes were prepared and were characterized pharmaceutically and biologically. METHODS The liposomes were prepared by the ethanol evaporation method and were characterized by quasi-elastic light scatteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac8bc69254a5547e7c25287061ffe3f4
https://doi.org/10.1097/00004424-199311000-00011
https://doi.org/10.1097/00004424-199311000-00011
Autor:
Jens Leike, H. Strunk, Andreas Sachse, Gabrielle Schuhmann-Giampieri, Udo P. Schmiedl, Werner Krause
Publikováno v:
The Lens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69c6be98f15d86614101d39d07ce4e49
https://pubmed.ncbi.nlm.nih.gov/8796571
https://pubmed.ncbi.nlm.nih.gov/8796571