Zobrazeno 1 - 10
of 300
pro vyhledávání: '"Jens Kreth"'
Publikováno v:
Frontiers in Oral Health, Vol 5 (2024)
Inflammatory dysbiotic diseases present an intriguing biological paradox. Like most other infectious disease processes, the alarm bells of the host are potently activated by tissue-destructive pathobionts, triggering a cascade of physiological respon
Externí odkaz:
https://doaj.org/article/5841f24297f04e56a107daaf797f5bf1
Publikováno v:
Frontiers in Oral Health, Vol 5 (2024)
Historically, the study of microbe-associated diseases has focused primarily on pathogens, guided by Koch's postulates. This pathogen-centric view has provided a mechanistic understanding of disease etiology and microbial pathogenesis. However, next-
Externí odkaz:
https://doaj.org/article/04ce0f1380dc4a36a5ca5939c8ecdb71
Autor:
Hua Qin, David Anderson, Zhengzhong Zou, Dustin Higashi, Christina Borland, Jens Kreth, Justin Merritt
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 2 (2024)
ABSTRACTMecA is a highly conserved adaptor protein encoded by prokaryotes from the Bacillota phylum. MecA mutants exhibit similar pleiotropic defects in a variety of organisms, although most of these phenotypes currently lack a mechanistic basis. Mec
Externí odkaz:
https://doaj.org/article/d1749319cebc4cf0a1ecdbd742776257
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT The study of human commensal bacteria began with the first observation of prokaryotes >340 years ago. Since then, the study of human-associated microbes has been justifiably biased toward the study of infectious pathogens. However, the role
Externí odkaz:
https://doaj.org/article/c2c74a3ccd464c5bad2c74574178d4c0
Publikováno v:
mSphere, Vol 8, Iss 3 (2023)
ABSTRACT The Streptococcus mutans genetic system offers a variety of strategies to rapidly engineer targeted chromosomal mutations. Previously, we reported the first S. mutans negative selection system that functions in a wild-type background. This s
Externí odkaz:
https://doaj.org/article/3d1cef0546964721abc7c5f03ffcb8b2
Autor:
Jens Kreth
Publikováno v:
Endodontic Topics. 22:127-127
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c74c92270c6c946d7e9b2d8bdae9f712
https://doi.org/10.1111/j.1601-1546.2012.0283_4.x
https://doi.org/10.1111/j.1601-1546.2012.0283_4.x
Publikováno v:
Brazilian Oral Research, Vol 36 (2022)
Abstract Although the commensal Streptococcus sanguinis [ S. sanguinis] is isolated from caries-free people, it can ferment carbohydrates producing acids. We aimed to characterize S. sanguinis cariogenic potential as a function of different enamel bi
Externí odkaz:
https://doaj.org/article/3fa40950a72e48b5abc60e7a8b7e1efb
Autor:
Dustin L. Higashi, Sean McGuire, Yasser M. Abdelrahman, Zhengzhong Zou, Hua Qin, David Anderson, Elizabeth A. Palmer, Jens Kreth, Justin Merritt
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 2 (2022)
ABSTRACT Parvimonas micra is a Gram-positive obligate anaerobe and a typical member of the human microbiome. P. micra is among the most highly enriched species at numerous sites of mucosal dysbiotic disease and is closely associated with the developm
Externí odkaz:
https://doaj.org/article/bf49c6e9f7794e62ae0435310f87f819
Autor:
Ulrike Redanz, Sylvio Redanz, Puthalayai Treerat, Sivaraman Prakasam, Li-Jung Lin, Justin Merritt, Jens Kreth
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Polymicrobial interactions with oral mucosal surfaces determine the health status of the host. While a homeostatic balance provides protection from oral disease, a dysbiotic polymicrobial community promotes tissue destruction and chronic oral disease
Externí odkaz:
https://doaj.org/article/43995369947a4eabb4941e46655def1f
Publikováno v:
Analytical Chemistry. 95:6332-6340
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e86f1f9ecf89bb7a7a52282a00ddd6b2
https://doi.org/10.1021/acs.analchem.2c05258
https://doi.org/10.1021/acs.analchem.2c05258