Zobrazeno 1 - 10
of 312
pro vyhledávání: '"Jens Hillengaß"'
Autor:
Elias K. Mai, Axel Nogai, Henk M. Lokhorst, Bronno van derHolt, Sonja Zweegman, Katja C. Weisel, Sandra Croockewit, Anna Jauch, Jens Hillengass, Marian Stevens‐Kroef, Marc S. Raab, Annemiek Broijl, Gerard M. J. Bos, Peter Brossart, Paula Ypma, Christine Hanoun, Uta Bertsch, Thomas Hielscher, Hans J. Salwender, Christoph Scheid, Hartmut Goldschmidt, Pieter Sonneveld
Publikováno v:
HemaSphere, Vol 8, Iss 11, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/60e59158ba384e1499fbae6e3c716563
Autor:
Lukas John, Alexandra M. Poos, Alexander Brobeil, Carolina Schinke, Stefanie Huhn, Nina Prokoph, Raphael Lutz, Barbara Wagner, Maurizio Zangari, Stephan M. Tirier, Jan-Philipp Mallm, Sabrina Schumacher, Dominik Vonficht, Llorenç Solé-Boldo, Sabine Quick, Simon Steiger, Moritz J. Przybilla, Katharina Bauer, Anja Baumann, Stefan Hemmer, Christoph Rehnitz, Christian Lückerath, Christos Sachpekidis, Gunhild Mechtersheimer, Uwe Haberkorn, Antonia Dimitrakopoulou-Strauss, Philipp Reichert, Bart Barlogie, Carsten Müller-Tidow, Hartmut Goldschmidt, Jens Hillengass, Leo Rasche, Simon F. Haas, Frits van Rhee, Karsten Rippe, Marc S. Raab, Sandra Sauer, Niels Weinhold
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract In multiple myeloma spatial differences in the subclonal architecture, molecular signatures and composition of the microenvironment remain poorly characterized. To address this shortcoming, we perform multi-region sequencing on paired random
Externí odkaz:
https://doaj.org/article/1de2b57c538f40e487f459cc7a327e33
Autor:
Jens Hillengass, Romain Lannes, Saeed Daneshmandi, Cameron Macdonald, Qi Yan, Jeeeun Choi, Prashant Singh, Ahmed Belal, Ronald Alberico, Ian Lund, Megan Schaefer, Sarah Parker, Nikhil Munshi, Kenneth Anderson, Mehmet Samur, Philip Mccarthy, Hemn Mohammadpour
Publikováno v:
HemaSphere, Vol 7, p e62848ef (2023)
Externí odkaz:
https://doaj.org/article/824362d6c0b24d9d9df6bf854ea4077a
Autor:
Shaji Kumar, Lawrence Baizer, Natalie S. Callander, Sergio A. Giralt, Jens Hillengass, Boris Freidlin, Antje Hoering, Paul G. Richardson, Elena I. Schwartz, Anthony Reiman, Suzanne Lentzsch, Philip L. McCarthy, Sundar Jagannath, Andrew J. Yee, Richard F. Little, Noopur S. Raje
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 6, Pp 1-11 (2022)
Abstract A wide variety of new therapeutic options for Multiple Myeloma (MM) have recently become available, extending progression-free and overall survival for patients in meaningful ways. However, these treatments are not curative, and patients eve
Externí odkaz:
https://doaj.org/article/0238267280cc4458be0fc24b8b97fe2d
Autor:
Maria A. Malik, Nathan W. Sweeney, Mohammad Jafri, Andriy Derkach, Cynthia Chmielewski, Peter A. Adintori, Sham Mailankody, Neha Korde, Carlyn R. Tan, Hani Hassoun, Malin Hultcrantz, Jens Hillengass, Susan E. McCann, Neil Iyengar, Saad Usmani, Sergio A. Giralt, Ola Landgren, Marcel R. M. van den Brink, Jennifer M. Ahlstrom, Alexander M. Lesokhin, Anita D’Souza, Susan Chimonas, Urvi A. Shah
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 4, Pp 1-5 (2022)
Externí odkaz:
https://doaj.org/article/68536ec941d147189e0677f18c00e7f0
Autor:
Maximilian Merz, Almuth Maria Anni Merz, Jie Wang, Lei Wei, Qiang Hu, Nicholas Hutson, Cherie Rondeau, Kimberly Celotto, Ahmed Belal, Ronald Alberico, AnneMarie W. Block, Hemn Mohammadpour, Paul K. Wallace, Joseph Tario, Jesse Luce, Sean T. Glenn, Prashant Singh, Megan M. Herr, Theresa Hahn, Mehmet Samur, Nikhil Munshi, Song Liu, Philip L. McCarthy, Jens Hillengass
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Osteolytic lesions (OL) are frequent in multiple myeloma (MM), but are poorly understood. Here, the authors characterise OLs in MM patient samples using single-cell RNA-seq, revealing genes that are specifically regulated in OL compared to random bon
Externí odkaz:
https://doaj.org/article/f796828f91bf49deafc2d56948663af8
Publikováno v:
Hemato, Vol 2, Iss 4, Pp 672-679 (2021)
Multiple myeloma and other plasma cell disorders infiltrate the bone marrow in different patterns. While some patients show a homogeneous distribution of the clonal plasma cells others present with focal accumulations, commonly called focal lesions.
Externí odkaz:
https://doaj.org/article/656a31c30a5d4fa5b72a1b69a5822165
Autor:
Marc-Andrea Baertsch, Elias K. Mai, Thomas Hielscher, Uta Bertsch, Hans J. Salwender, Markus Munder, Stephan Fuhrmann, Ulrich Dührsen, Peter Brossart, Kai Neben, Jana Schlenzka, Christina Kunz, Marc S. Raab, Jens Hillengaß, Anna Jauch, Anja Seckinger, Dirk Hose, Steffen Luntz, Pieter Sonneveld, Henk Lokhorst, Hans Martin, Martin Goerner, Martin Hoffmann, Hans-Walter Lindemann, Helga Bernhard, Igor W. Blau, Christof Scheid, Britta Besemer, Katja C. Weisel, Mathias Hänel, Jan Dürig, Hartmut Goldschmidt, German-Speaking Myeloma Multicenter Group (GMMG)
Publikováno v:
Blood Cancer Journal, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Lenalidomide (LEN) maintenance (MT) post autologous stem cell transplantation (ASCT) is standard of care in newly diagnosed multiple myeloma (MM) but has not been compared to other agents in clinical trials. We retrospectively compared borte
Externí odkaz:
https://doaj.org/article/c1262202ec704fb3bc2b8009125681e4
Autor:
Hans Salwender, Uta Bertsch, Katja Weisel, Jan Duerig, Christina Kunz, Axel Benner, Igor W. Blau, Marc Steffen Raab, Jens Hillengass, Dirk Hose, Stefanie Huhn, Michael Hundemer, Mindaugas Andrulis, Anna Jauch, Andrea Seidel-Glaetzer, Hans-Walter Lindemann, Manfred Hensel, Stefan Fronhoffs, Uwe Martens, Timon Hansen, Mohammed Wattad, Ullrich Graeven, Markus Munder, Roland Fenk, Mathias Haenel, Christof Scheid, Hartmut Goldschmidt
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background Despite major advances in therapy, multiple myeloma is still an incurable malignancy in the majority of patients. To increase survival, deeper remissions (i.e. CR) translating into longer PFS need to be achieved. Incorporation of
Externí odkaz:
https://doaj.org/article/5f886bfc9cbd44f2ba2caaa95f24d69d
Autor:
Molly Went, Amit Sud, Asta Försti, Britt-Marie Halvarsson, Niels Weinhold, Scott Kimber, Mark van Duin, Gudmar Thorleifsson, Amy Holroyd, David C. Johnson, Ni Li, Giulia Orlando, Philip J. Law, Mina Ali, Bowang Chen, Jonathan S. Mitchell, Daniel F. Gudbjartsson, Rowan Kuiper, Owen W. Stephens, Uta Bertsch, Peter Broderick, Chiara Campo, Obul R Bandapalli, Hermann Einsele, Walter A. Gregory, Urban Gullberg, Jens Hillengass, Per Hoffmann, Graham H. Jackson, Karl-Heinz Jöckel, Ellinor Johnsson, Sigurður Y. Kristinsson, Ulf-Henrik Mellqvist, Hareth Nahi, Douglas Easton, Paul Pharoah, Alison Dunning, Julian Peto, Federico Canzian, Anthony Swerdlow, Rosalind A. Eeles, ZSofia Kote-Jarai, Kenneth Muir, Nora Pashayan, Jolanta Nickel, Markus M. Nöthen, Thorunn Rafnar, Fiona M. Ross, Miguel Inacio da Silva Filho, Hauke Thomsen, Ingemar Turesson, Annette Vangsted, Niels Frost Andersen, Anders Waage, Brian A. Walker, Anna-Karin Wihlborg, Annemiek Broyl, Faith E. Davies, Unnur Thorsteinsdottir, Christian Langer, Markus Hansson, Hartmut Goldschmidt, Martin Kaiser, Pieter Sonneveld, Kari Stefansson, Gareth J. Morgan, Kari Hemminki, Björn Nilsson, Richard S. Houlston, The PRACTICAL consortium
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Multiple myeloma is a cancer of the plasma cells, and the complete aetiology of the disease is still unclear. Here the authors perform an additional GWAS analysis followed by a meta-analysis with existing GWAS and replication genotyping and identify
Externí odkaz:
https://doaj.org/article/af73d8d01835421aac1fd29b48af6093