Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jens Hennecke"'
Autor:
Jens Hennecke, Don C. Wiley
Publikováno v:
Journal of Experimental Medicine. 195:571-581
The α/β T cell receptor (TCR) HA1.7 specific for the hemagglutinin (HA) antigen peptide from influenza A virus is HLA-DR1 restricted but cross-reactive for the HA peptide presented by the allo-major histocompatibility complex (MHC) class II molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c68d746d51c79ab26839f542c4c3f6f
https://doi.org/10.1084/jem.20011194
https://doi.org/10.1084/jem.20011194
Publikováno v:
Proteins: Structure, Function, and Genetics. 37:253-263
The disulfide oxidoreductase DsbA is a strong oxidant of protein thiols and is required for efficient disulfide bond formation in the bacterial periplasm. DsbA contains two tryptophans: W76 and W126. The fluorescence of W76 changes upon reduction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd441d72e6215228a9447216e2d8fce
https://doi.org/10.1002/(sici)1097-0134(19991101)37:2<253::aid-prot10>3.0.co
https://doi.org/10.1002/(sici)1097-0134(19991101)37:2<253::aid-prot10>3.0.co
Publikováno v:
Journal of Molecular Biology. 286:1197-1215
One of the key questions in protein folding is whether polypeptide chains require unique nucleation sites to fold to the native state. In order to identify possible essential polypeptide segments for folding, we have performed a complete circular per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d4dbe7a636ff1f22df6e00f92f341f2
https://doi.org/10.1006/jmbi.1998.2531
https://doi.org/10.1006/jmbi.1998.2531
Publikováno v:
Journal of Biological Chemistry. 272:21692-21699
Disulfide oxidoreductases are structurally related proteins that share the thioredoxin fold and a catalytic disulfide bond that is located at the N terminus of an alpha-helix. The different redox potentials of these enzymes varying from -270 mV for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5917011fe96b646ee1c2be8b6dac8d8d
https://doi.org/10.1074/jbc.272.35.21692
https://doi.org/10.1074/jbc.272.35.21692
Publikováno v:
Biochemistry. 36:6391-6400
The disulfide oxidoreductase DsbA is a strong oxidant of protein thiols and required for efficient disulfide bond formation in the bacterial periplasm. The enzyme consists of a thioredoxin-like domain and a second, alpha-helical domain which is inser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08922103fe4f4f49e2ae50a70db4b638
https://doi.org/10.1021/bi963017w
https://doi.org/10.1021/bi963017w
Publikováno v:
Journal of Biological Chemistry. 272:189-195
The catalytic disulfide bond Cys30-Cys33 of the disulfide oxidoreductase DsbA from Escherichia coli is located at the amino terminus of an alpha-helix, which has a kink caused by insertion of a tripeptide (residues 38-40). The oxidative force of DsbA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f4103fd60dc0f275f547d1245931b5b
https://doi.org/10.1074/jbc.272.1.189
https://doi.org/10.1074/jbc.272.1.189
Publikováno v:
Journal of molecular biology. 327(1)
Fluorescence resonance energy transfer (FRET) was used to establish a novel in vivo screening system that allows rapid detection of protein folding and protein variants with increased thermodynamic stability in the cytoplasm of Escherichia coli. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6afebd298350f0b6d2e75ba30f1193cf
https://pubmed.ncbi.nlm.nih.gov/12614622
https://pubmed.ncbi.nlm.nih.gov/12614622
Autor:
Jens, Hennecke, Don C, Wiley
Publikováno v:
The Journal of Experimental Medicine
The alpha/beta T cell receptor (TCR) HA1.7 specific for the hemagglutinin (HA) antigen peptide from influenza A virus is HLA-DR1 restricted but cross-reactive for the HA peptide presented by the allo-major histocompatibility complex (MHC) class II mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::02afa3bfa8f0476739bf2f1b5c7c6a96
https://pubmed.ncbi.nlm.nih.gov/11877480
https://pubmed.ncbi.nlm.nih.gov/11877480
Publikováno v:
Topics in Fluorescence Spectroscopy ISBN: 9780306464515
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7ac47afdf68d9fc33b9e53a64b50568
https://doi.org/10.1007/0-306-47102-7_6
https://doi.org/10.1007/0-306-47102-7_6
Autor:
Don C. Wiley, Jens Hennecke
Publikováno v:
Cell. 104(1)
X-ray crystal structures of αβTCRs bound to MHCI and MHCII molecules with bound antigenic peptides reveals the atomic contacts upon which MHC restricted T cell recognition is based. Very different signals can result from very similar structures and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::835cfae1ccb7b3dbf788a1bebade6300
https://pubmed.ncbi.nlm.nih.gov/11163234
https://pubmed.ncbi.nlm.nih.gov/11163234