Výsledky vyhledávání - "Jens H Westhoff"

Akademický článek

Urinary Tissue Inhibitor of Metalloproteinase-2 (TIMP-2) • Insulin-Like Growth Factor-Binding Protein 7 (IGFBP7) Predicts Adverse Outcome in Pediatric Acute Kidney Injury.

Autor: Jens H Westhoff, Burkhard Tönshoff, Sina Waldherr, Johannes Pöschl, Ulrike Teufel, Timm H Westhoff, Alexander Fichtner

Publikováno v: PLoS ONE, Vol 10, Iss 11, p e0143628 (2015)

The G1 cell cycle inhibitors tissue inhibitor of metalloproteinase-2 (TIMP-2) and insulin-like growth factor-binding protein 7 (IGFBP7) have been identified as promising biomarkers for the prediction of adverse outcomes including renal replacement th

Externí odkaz: https://doaj.org/article/c1fab552e64743a290e53302caae5b56

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Akademický článek

Development of an automated imaging pipeline for the analysis of the zebrafish larval kidney.

Autor: Jens H Westhoff, Stefan Giselbrecht, Miriam Schmidts, Sebastian Schindler, Philip L Beales, Burkhard Tönshoff, Urban Liebel, Jochen Gehrig

Publikováno v: PLoS ONE, Vol 8, Iss 12, p e82137 (2013)

The analysis of kidney malformation caused by environmental influences during nephrogenesis or by hereditary nephropathies requires animal models allowing the in vivo observation of developmental processes. The zebrafish has emerged as a useful model

Externí odkaz: https://doaj.org/article/196d3fdff73e4263a2af9ab55b68685c

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Rescue of respiratory failure in pulmonary alveolar proteinosis due to pathogenic MARS1 variants

Autor: Dominik Schöndorf, Karl Reiter, Dominic Lenz, Carola Schön, Matias Wagner, Heiko Brennenstuhl, Florian Gesenhues, Gajja S. Salomons, Matthias Griese, Jens H Westhoff, Elias Seidl, Tina Heinzmann, Marisa I. Mendes, Mirjam Stahl, Desirée E.C. Smith, Christian Staufner, Thomas Longerich, Holger Prokisch, Olaf Sommerburg

Publikováno v: Pediatric pulmonology, 55(11), 3057-3066. Wiley-Liss Inc.
Pediatr. Pulmonol. 55, 3057-3066 (2020)
Pediatric Pulmonology, 55(11), 3057-3066. Wiley-Liss Inc.
Lenz, D, Stahl, M, Seidl, E, Schöndorf, D, Brennenstuhl, H, Gesenhues, F, Heinzmann, T, Longerich, T, Mendes, M I, Prokisch, H, Salomons, G S, Schön, C, Smith, D E C, Sommerburg, O, Wagner, M, Westhoff, J H, Reiter, K, Staufner, C & Griese, M 2020, ' Rescue of respiratory failure in pulmonary alveolar proteinosis due to pathogenic MARS1 variants ', Pediatric Pulmonology, vol. 55, no. 11, pp. 3057-3066 . https://doi.org/10.1002/ppul.25031

Background: Pulmonary alveolar proteinosis (PAP) is a heterogeneous condition with more than 100 different underlying disorders that need to be differentiated to target therapeutic options, which are generally limited. Methods: The clinical course of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc7093bf152485b881b8465b810e87e
http://www.scopus.com/inward/record.url?scp=85090311851&partnerID=8YFLogxK

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An Experimental Workflow for Studying Barrier Integrity, Permeability, and Tight Junction Composition and Localization in a Single Endothelial Cell Monolayer: Proof of Concept

Autor: Damir Krunic, Felix Bestvater, Michael Hausmann, Jens H Westhoff, Jana Heigwer, Sotirios G. Zarogiannis, David Ridinger, Stefan Terjung, Iva Marinovic, Claus Peter Schmitt, Georg Hildenbrand, Eszter Levai, Conghui Zhang, Franz Schaefer, Maria Bartosova

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 8178, p 8178 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 15

Endothelial and epithelial barrier function is crucial for the maintenance of physiological processes. The barrier paracellular permeability depends on the composition and spatial distribution of the cell-to-cell tight junctions (TJ). Here, we provid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa4dd63422a3220f59a58284eae52979
https://www.mdpi.com/1422-0067/22/15/8178

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Urinary acute kidney injury biomarkers in very low-birth-weight infants on indomethacin for patent ductus arteriosus

Autor: Franz Schaefer, Timm H. Westhoff, Alexander Fichtner, Burkhard Tönshoff, Johannes Pöschl, Thomas Bruckner, Bernd Beedgen, Sina Waldherr, Jens H. Westhoff

Publikováno v: Pediatric Research. 85:678-686

Serum creatinine (SCr)- or urine output-based definitions of acute kidney injury (AKI) have important limitations in neonates. This study evaluates the diagnostic value of urinary biomarkers in very low-birth-weight (VLBW) infants receiving indometha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::888089c674a31d3e18b43e40af9e1a5d
https://doi.org/10.1038/s41390-019-0332-9

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Next-generation sequencing diagnostics of bacteremia in pediatric sepsis

Autor: Thorsten Brenner, Manuel Feisst, Ursula Felderhoff-Müser, Jens H. Westhoff, Christina Klose, Georg F. Hoffmann, Steffen Luntz, Kai Sohn, Christian Dohna-Schwake, Thomas Bruckner, Sebastian Decker, Caroline Skolik, Thomas Schmoch, Annabell Skarabis, Markus A. Weigand

Publikováno v: Medicine

INTRODUCTION: Sepsis and septic shock are the most severe forms of infection affecting predominantly elderly people, preterm and term neonates, and young infants. Even in high-income countries sepsis causes about 8% of admissions to pediatric intensi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::416ff625de616ccc1871a5987de15e8b
https://www.ncbi.nlm.nih.gov/pubmed/34160425

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