Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jens Fricke"'
Autor:
Britta Eggenreich, Vignesh Rajamanickam, David Johannes Wurm, Jens Fricke, Christoph Herwig, Oliver Spadiut
Publikováno v:
Microbial Cell Factories, Vol 16, Iss 1, Pp 1-10 (2017)
Abstract Background Cell disruption is a key unit operation to make valuable, intracellular target products accessible for further downstream unit operations. Independent of the applied cell disruption method, each cell disruption process must be eva
Externí odkaz:
https://doaj.org/article/cbe651cb3d9e42d09c9a79d6a3bce2b8
Autor:
Julian Kopp, Christoph Slouka, Sophia Ulonska, Julian Kager, Jens Fricke, Oliver Spadiut, Christoph Herwig
Publikováno v:
Bioengineering, Vol 5, Iss 1, p 1 (2017)
The Gram-negative bacterium E. coli is the host of choice for a multitude of used recombinant proteins. Generally, cultivation is easy, media are cheap, and a high product titer can be obtained. However, harsh induction procedures using isopropyl β-
Externí odkaz:
https://doaj.org/article/174ddc87c677488c9c5b2d3b4d35b81c
Autor:
Christoph Slouka, Georg Christoph Brunauer, Julian Kopp, Michael Strahammer, Jens Fricke, Jürgen Fleig, Christoph Herwig
Publikováno v:
Chemosensors, Vol 5, Iss 3, p 24 (2017)
Today’s yeast total biomass and viability measurements during the brewing process are dependent on offline methods such as methylene blue or florescence dye-based staining, and/or the usage of flow cytometric measurements. Additionally, microscopic
Externí odkaz:
https://doaj.org/article/d73d817a0eab43fa881d30e1799f1a42
Publikováno v:
Process Biochemistry. 70:20-28
Although corn steep liquor (CSL) is a commonly applied raw material in biopharmaceutical production processes, its mechanistic impact on process performance is still not completely unraveled. It is a multicomponent and multiphase matrix, including fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9404ecfad764ee525b3ee62ddfd99470
https://doi.org/10.1016/j.procbio.2018.04.008
https://doi.org/10.1016/j.procbio.2018.04.008
Publikováno v:
Engineering in Life Sciences. 18:204-214
The shift from lactate production to consumption in CHO cell metabolism is a key event during cell culture cultivations and is connected to increased culture longevity and final product titers. However, the mechanisms controlling this metabolic shift
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b62a0cf46743e45844aa8d306a941948
https://doi.org/10.1002/elsc.201700131
https://doi.org/10.1002/elsc.201700131
Autor:
Daniela Ehgartner, Julian Kager, Sarah Heinzl, Manuela Frank, Jens Fricke, Christoph Herwig, Thomas Hartmann, Lukas Veiter
Publikováno v:
Chemical Engineering Science. 172:32-41
Increasing pressure on product quality and quantity pushes solutions of process control to be a central issue in pharmaceutical bioprocesses. Especially online biomass estimation, and further control of the specific growth rate are of central importa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a9894c80636cf65ede742b8525e4813
https://doi.org/10.1016/j.ces.2017.06.020
https://doi.org/10.1016/j.ces.2017.06.020
Publikováno v:
Applied Microbiology and Biotechnology
An important parameter in filamentous bioreactor cultivations is the morphology of the fungi, due to its interlink to productivity and its dependency on process conditions. Filamentous fungi show a large variety of morphological forms in submerged cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eec009d36a8d7d85a83ebc858a6fea6
https://doi.org/10.1007/s00253-017-8475-2
https://doi.org/10.1007/s00253-017-8475-2
Autor:
Adrian Hill, Micha Gryschka, Rachel Honnert, Jens Fricke, Andrew T. Lesage, Jan Chylik, Stephan R. de Roode, A. Pier Siebesma, Lorenzo Tomassini, Steven K. Krueger, Andrew S. Ackerman, Christine Lac, Paul R. Field, Thomas Frederikse
Publikováno v:
Journal of Advances in Modeling Earth Systems, 11(3)
Journal of Advances in Modeling Earth Systems
Journal of Advances in Modeling Earth Systems
To quantify the turbulent transport at gray zone length scales between 1 and 10 km, the Lagrangian evolution of the CONSTRAIN cold air outbreak case was simulated with seven large eddy models. The case is characterized by rather large latent and sens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cefc697bf4d168dad933bfe62da5cbe5
http://resolver.tudelft.nl/uuid:5e28cffe-31f6-4dd4-8ba1-8c363d66d4f6
http://resolver.tudelft.nl/uuid:5e28cffe-31f6-4dd4-8ba1-8c363d66d4f6
Publikováno v:
Applied Microbiology and Biotechnology
Spore inoculum quality in filamentous bioprocesses is a critical parameter associated with viable spore concentration (1) and spore germination (2). It influences pellet morphology and, consequently, process performance. The state-of-the-art method t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1e8e2bbf3b17e97fb025b9fddf69c8
https://doi.org/10.1007/s00253-016-7787-y
https://doi.org/10.1007/s00253-016-7787-y
Autor:
Jens Fricke, Markus Brillmann, Wieland Reichelt, Peter Thurrold, Julian Kager, Christoph Herwig
Publikováno v:
Engineering in Life Sciences. 16:720-730
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::084ac60180cc6239aae84c77dd8ef667
https://doi.org/10.1002/elsc.201500182
https://doi.org/10.1002/elsc.201500182