Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jens F, Bak"'
Publikováno v:
Diabetes. 40:1740-1745
Based on recent studies of the abnormal physiology and biochemistry of the glycogen synthesis in skeletal muscle of non-insulin-dependent diabetes mellitus (NIDDM) patients and their first-degree relatives, the key enzyme of this pathway, glycogen sy
Publikováno v:
Metabolism. 40:830-835
Insulin receptor function, glycogen synthase activity, and activation by phosphatases were studied in biopsies of human skeletal muscle under conditions of hyperglycemia and/or hyperinsulinemia for 150 minutes. Twenty-one healthy volunteers underwent
Publikováno v:
The American Journal of Medicine. 90:S22-S28
The effect of glibenclamide treatment on insulin action in isolated fat cells was studied in eight moderately obese patients with non-insulin-dependent diabetes mellitus (NIDDM). Insulin receptor binding and the effect of insulin on glucose transport
Autor:
Oluf Pedersen, Jens F. Bak
Publikováno v:
Diabetes Research and Clinical Practice. 14:S61-S64
Sulfonylureas are widely used drugs in the treatment of NIDDM when diet treatment is unsuccessful. In addition to their pancreatic effects sulfonylureas have been reported to have insulin-like and insulin-potentiating actions in vitro with respect bo
Autor:
Sten Lund, Per Heden Andersen, Jens F. Bak, Jeffrey S. Flier, Oluf Pedersen, Barbara B. Kahn, David E. Moller
Publikováno v:
Diabetes. 39:865-870
Studies of experimental diabetes in rodents induced by the β-cell toxin streptozocin have shown that the insulin-resistant glucose transport of peripheral tissues (muscle and adipose) in these animals can be ascribed in part to a pretranslational re
Autor:
Steen B, Pedersen, Dorthe, Møller, Jørgen Bendix, Holme, Peter M, Funch-Jensen, Lars Bolvig, Hansen, Hanne, Gammelgaard, Jens F, Bak, Bjørn, Richelsen
Publikováno v:
Ugeskrift for laeger. 167(18)
Publikováno v:
Metabolism: clinical and experimental. 44(12)
Fluoxetine (F) is a specific serotonin-reuptake inhibitor that has been shown to promote weight loss and improve glycemic control in obese diabetic patients. To study its long-term metabolic effect, 40 obese patients with non-insulin -dependent diabe
Publikováno v:
Metabolism: clinical and experimental. 42(8)
Insulin resistance is commonly associated with obesity. The present study was performed to investigate the relative importance of total fat mass versus localization of adipose tissue in insulin-stimulated glucose disposal (Rd) and skeletal muscle gly
Publikováno v:
Diabetes Research and Clinical Practice. 1:323-326
125I-Insulin binding to monocytes from 14 gestational diabetics was measured before and after 6 weeks of treatment with a 5500 kJ, low-fat, low-sucrose diet. After the hypoenergetic feeding of gestational diabetics, fasting plasma concentrations of g
Publikováno v:
Acta Endocrinologica. 121:744-750
To examine subcellular mechanisms behind the pathogenesis of peripheral insulin resistance in chronic uremic patients, insulin receptor function and glycogen synthase activity were studied in biopsies of skeletal muscle obtained during renal transpla