Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Jens Ehmcke"'
Autor:
Ruth Kläver, Victoria Sánchez, Oliver S Damm, Klaus Redmann, Elisabeth Lahrmann, Reinhild Sandhowe-Klaverkamp, Christian Rohde, Joachim Wistuba, Jens Ehmcke, Stefan Schlatt, Jörg Gromoll
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117839 (2015)
Establishment and maintenance of the correct epigenetic code is essential for a plethora of physiological pathways and disturbed epigenetic patterns can provoke severe consequences, e.g. tumour formation. In recent years, epigenetic drugs altering th
Externí odkaz:
https://doaj.org/article/491567e9a0f7427684f680ac89e862e2
Autor:
Birgit Westernströer, Nicole Terwort, Jens Ehmcke, Joachim Wistuba, Stefan Schlatt, Nina Neuhaus
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e112598 (2014)
In mice the chemokine Cxcl12 and its receptor Cxcr4 participate in maintenance of the spermatogonial population during postnatal development. More complexity arises since Cxcl12 also binds to the non-classical/atypical chemokine receptor Cxcr7. We ex
Externí odkaz:
https://doaj.org/article/6ec19420b40c4089a607670c15fe380b
Publikováno v:
Der Urologe. 55:868-876
Hintergrund Eine ausreichend hohe und ungestorte Produktion befruchtungsfahiger Spermien ist Voraussetzung fur das Erzielen einer Vaterschaft. Damit steht der Prozess der Spermatogenese im Mittelpunkt der mannlichen Fertilitat. Der Hoden enthalt aber
Publikováno v:
Journal of Medical Primatology. 45:105-111
Background Hypothalamic kisspeptin–kisspeptin receptor signalling in primates ensures the successful progression into puberty during development and maintenance of reproductive capacity during adulthood. Human testis has been shown to express high-
Publikováno v:
Primate Biology. 2:1-8
The common marmoset (Callithrix jacchus) is a New World primate that exhibits a man-like adult testicular organization. Aims: this study examines the pubertal testicular development in the common marmoset. Material and methods: immature male common m
Autor:
Fedra Gottardo, Klaus Redmann, Frank Tuettelmann, Sabine Kliesch, Joachim Wistuba, Jens Ehmcke, Ursula Eppelmann, Birgit Westernstroeer, Frank Wuebbeling, Con Mallidis, Martin Burger, Nina Kossack
Publikováno v:
Cell and Tissue Research. 354:623-632
TCam-2 cells are the main in vitro model for investigations into seminomatous tumors. However, despite their widespread use, questions remain regarding the cells' homogeneity and consequently how representative they are of seminomas. We assess the TC
Publikováno v:
Andrologia. 46:610-617
Kisspeptin-Kiss1R signalling in mammals has been implicated as an integral part of the reproductive cascade. Kisspeptinergic neurons upstream of GnRH neurons are involved in the activation of the hypothalamic GnRH pulse generator during pubertal onse
Publikováno v:
Cancer Research. 72:5174-5178
Boys faced with future sterility as a result of the need of a sterilizing cancer therapy might avoid this fate by engraftment of cryopreserved immature testicular tissue after therapy is completed. Efforts to address this important survivorship issue
Publikováno v:
Spermatogenesis
Many previous studies have aimed at spermatogenesis of male murine germ cells in vitro, but no efficient system has been established yet that covers the entire process of mammalian spermatogenesis in a culture dish permanently. In this review, we rep
Autor:
K. Eildermann, Sabine Kliesch, Stefan Schlatt, N. Aeckerle, Joerg Gromoll, M. Heistermann, Jens Ehmcke, H. Christiansen, Katharina Debowski, Maren Godmann, S. Schweyer, Martin Bergmann, R. Behr
Publikováno v:
Cells Tissues Organs. 196:206-220
SALL4 (sal-like protein 4) is a pluripotency transcription fac- tor, which is highly expressed in embryonic stem (ES) cells and which is essential for mo use preimplantation develop- ment. In adult mouse organs, Sall4 mRNA is highly expressed in the