Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Jens De, Vos"'
Autor:
Nick Devoogdt, Tony Lahoutte, Michael R. Zalutsky, Vicky Caveliers, Geert Raes, Sam Massa, Yann G.J. Sterckx, Marek Pruszynski, Catarina Xavier, Jens De Vos, Matthias D'Huyvetter
Supplementary Table S5 shows the ex vivo biodistribution of 131I-2Rs15d after 1h in mice with BT474/M1 xenografts that were pre-treated 72h earlier with a 100-fold molar excess of trastuzumab, pertuzumab or a combination of both.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2734222273f7d0ee6abe43e986834f4
https://doi.org/10.1158/1078-0432.22468586.v1
https://doi.org/10.1158/1078-0432.22468586.v1
Autor:
Nick Devoogdt, Tony Lahoutte, Michael R. Zalutsky, Vicky Caveliers, Geert Raes, Sam Massa, Yann G.J. Sterckx, Marek Pruszynski, Catarina Xavier, Jens De Vos, Matthias D'Huyvetter
Purpose: Camelid single-domain antibody-fragments (sdAb) have beneficial pharmacokinetic properties, and those targeted to HER2 can be used for imaging of HER2-overexpressing cancer. Labeled with a therapeutic radionuclide, they may be used for HER2-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0df94826128d37a28124562b009a8d4e
https://doi.org/10.1158/1078-0432.c.6527000.v1
https://doi.org/10.1158/1078-0432.c.6527000.v1
Autor:
Nick Devoogdt, Tony Lahoutte, Michael R. Zalutsky, Vicky Caveliers, Geert Raes, Sam Massa, Yann G.J. Sterckx, Marek Pruszynski, Catarina Xavier, Jens De Vos, Matthias D'Huyvetter
A detailed description of the materials and methods used for the HER2-2Rs15d structure determination, the radioiodination of sdAbs, and all flow cytometry experiments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1fb4552e292abbaed6e7e922ede3c0b
https://doi.org/10.1158/1078-0432.22468601.v1
https://doi.org/10.1158/1078-0432.22468601.v1
Autor:
Nick Devoogdt, Tony Lahoutte, Michael R. Zalutsky, Vicky Caveliers, Geert Raes, Sam Massa, Yann G.J. Sterckx, Marek Pruszynski, Catarina Xavier, Jens De Vos, Matthias D'Huyvetter
Supplementary figure S1 details the HER2-epitope recognized by 2Rs15d compared to those reported for other described HER2-binders and a view of HER2-ÂÃ,â2Rs15d interactions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b2c09a3063a53f6722e54527b5aa027
https://doi.org/10.1158/1078-0432.22468583.v1
https://doi.org/10.1158/1078-0432.22468583.v1
Autor:
Marleen Keyaerts, Frank van der Aa, Ilse Vaneycken, Matthias D'Huyvetter, Tony Lahoutte, Hendrik Everaert, Albert D. Windhorst, Vicky Caveliers, Nick Devoogdt, Pieterjan Gykiere, Geert Raes, N. Harry Hendrikse, Jens De Vos, Jos L E Eersels, Johannes Heemskerk, Christel Fontaine, Marian Vanhoeij, François Duhoux
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 62(8), 1097-1105
D'Huyvetter, M, Vos, J D, Caveliers, V, Vaneycken, I, Heemskerk, J, Duhoux, F P, Fontaine, C, Vanhoeij, M, Windhorst, A D, Aa, F V D, Hendrikse, N H, Eersels, J L E, Everaert, H, Gykiere, P, Devoogdt, N, Raes, G, Lahoutte, T & Keyaerts, M 2021, ' Phase I Trial of 131I-GMIB-Anti-HER2-VHH1, a New Promising Candidate for HER2-Targeted Radionuclide Therapy in Breast Cancer Patients ', Journal of nuclear medicine : official publication, Society of Nuclear Medicine, vol. 62, no. 8, pp. 1097-1105 . https://doi.org/10.2967/jnumed.120.255679
D'Huyvetter, M, Vos, J D, Caveliers, V, Vaneycken, I, Heemskerk, J, Duhoux, F P, Fontaine, C, Vanhoeij, M, Windhorst, A D, Aa, F V D, Hendrikse, N H, Eersels, J L E, Everaert, H, Gykiere, P, Devoogdt, N, Raes, G, Lahoutte, T & Keyaerts, M 2021, ' Phase I Trial of 131I-GMIB-Anti-HER2-VHH1, a New Promising Candidate for HER2-Targeted Radionuclide Therapy in Breast Cancer Patients ', Journal of nuclear medicine : official publication, Society of Nuclear Medicine, vol. 62, no. 8, pp. 1097-1105 . https://doi.org/10.2967/jnumed.120.255679
Introduction:131I-GMIB-Anti-HER2-VHH1 is a targeted radionuclide theranostic agent directed at HER2 expressing cancers. VHH1 is a single domain antibody fragment covalently linked to therapeutic radio-iodine 131I via the linker SGMIB. The Phase I stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5332bb7a8f8e41c596fc523593f63dc0
https://research.vumc.nl/en/publications/8c6852db-7dae-40ad-b98a-16a2ca7c2938
https://research.vumc.nl/en/publications/8c6852db-7dae-40ad-b98a-16a2ca7c2938
Autor:
Matthias, D'Huyvetter, Jens De, Vos, Vicky, Caveliers, Ilse, Vaneycken, Johannes, Heemskerk, Francois P, Duhoux, Christel, Fontaine, Marian, Vanhoeij, Albert D, Windhorst, Frank van der, Aa, N Harry, Hendrikse, Jos L E, Eersels, Hendrik, Everaert, Pieterjan, Gykiere, Nick, Devoogdt, Geert, Raes, Tony, Lahoutte, Marleen, Keyaerts
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 62(8)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6fa67d9bb796d6fd000bb5dcb97ccbee
https://pubmed.ncbi.nlm.nih.gov/33277400
https://pubmed.ncbi.nlm.nih.gov/33277400
Autor:
Catarina Xavier, Yann G.-J. Sterckx, Michael R. Zalutsky, Geert Raes, Vicky Caveliers, Sam Massa, Marek Pruszynski, Nick Devoogdt, Tony Lahoutte, Matthias D'Huyvetter, Jens De Vos
Publikováno v:
Clinical Cancer Research. 23:6616-6628
Purpose: Camelid single-domain antibody-fragments (sdAb) have beneficial pharmacokinetic properties, and those targeted to HER2 can be used for imaging of HER2-overexpressing cancer. Labeled with a therapeutic radionuclide, they may be used for HER2-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09371574e9840eee5a3f88303a94ec57
https://doi.org/10.1158/1078-0432.ccr-17-0310
https://doi.org/10.1158/1078-0432.ccr-17-0310
Publikováno v:
Acta orthopaedica Belgica. 83(3)
The thumb contributes approximately 40 percent of hand function. In the case of an amputation, where replantation/revascularisation is impossible, a reconstruction should be planned as the second best treatment. Morrison described in 1980 the techniq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::551c67beed675867faac730c67e94b7d
https://pubmed.ncbi.nlm.nih.gov/30423649
https://pubmed.ncbi.nlm.nih.gov/30423649
Autor:
Ulrich Wernery, Tony Lahoutte, Jens De Vos, Luc Bouwens, Iris Mathijs, Serge Muyldermans, Catarina Xavier, Sam Massa, Nick Devoogdt
Publikováno v:
Vrije Universiteit Brussel
Purpose Molecular imaging has the potential to provide quantitative information about specific biological aspects of developing atherosclerotic lesions. This requires the generation of reliable, highly specific plaque tracers. This study reports a ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3ff72b0973007f21006586f80a73024
https://doi.org/10.1007/s11307-014-0731-6
https://doi.org/10.1007/s11307-014-0731-6
Autor:
Catarina Xavier, Pieter In 'T Veld, Sam Massa, Decio L. Eizirik, Jens De Vos, Iris Mathijs, Serge Goldman, Carmen Capito, Stéphane Demine, Piero Marchetti, Raphael Scharfmann, Dominique Egrise, Luc Bouwens, Alexander Balhuizen, Nick Devoogdt, Jean-Valery Turatsinze, Tony Lahoutte, Isabelle Millard, Olatz Villate, Serge Muyldermans
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific reports, 7 (1
Scientific Reports
Scientific reports, 7 (1
Scientific Reports
There are presently no reliable ways to quantify endocrine cell mass (ECM) in vivo, which prevents an accurate understanding of the progressive beta cell loss in diabetes or following islet transplantation. To address this unmet need, we coupled RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d49aa6311bd2f27219f65a50df1c0cd
http://hdl.handle.net/11568/880513
http://hdl.handle.net/11568/880513