Zobrazeno 1 - 10 of 21 pro vyhledávání: '"Jens Damsgaard"'
1
Akademický článek
α7 and β2 Nicotinic Acetylcholine Receptor Subunits Form Heteromeric Receptor Complexes that Are Expressed in the Human Cortex and Display Distinct Pharmacological Properties.
Autor: Morten Skøtt Thomsen, Ruud Zwart, Daniel Ursu, Majbrit Myrup Jensen, Lars Hageman Pinborg, Gary Gilmour, Jie Wu, Emanuele Sher, Jens Damsgaard Mikkelsen
Publikováno v: PLoS ONE, Vol 10, Iss 6, p e0130572 (2015)
The existence of α7β2 nicotinic acetylcholine receptors (nAChRs) has recently been demonstrated in both the rodent and human brain. Since α7-containing nAChRs are promising drug targets for schizophrenia and Alzheimer's disease, it is critical to
Externí odkaz: https://doaj.org/article/2cc02c47cc8244f3991aa4db270c3f4b
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4
Epigenetic regulation of Arc and c-Fos in the hippocampus after acute electroconvulsive stimulation in the rat
Autor: Jens Damsgaard Mikkelsen, Mads Dyrvig, Jacek Lichota, Henrik H. Hansen, David P.D. Woldbye, Søren H. Christiansen
Publikováno v: Johannesen, M D, Hansen, H H, Christiansen, S H, Woldbye, D P D, Mikkelsen, J D & Lichota, J 2012, ' Epigenetic regulation of Arc and c-Fos in the hippocampus after acute electroconvulsive stimulation in the rat ', Brain Research Bulletin, vol. 88, no. 5, pp. 507–513 . https://doi.org/10.1016/j.brainresbull.2012.05.004
Electroconvulsive stimulation (ECS) remains one of the most effective treatments of major depression. However, the underlying molecular changes still remain to be elucidated. Since ECS causes rapid and significant changes in gene expression we have l
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e12f147304c6408799eb02ae10844474
https://doi.org/10.1016/j.brainresbull.2012.05.004
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5
Kv7 channels: interaction with dopaminergic and serotonergic neurotransmission in the CNS
Autor: Susana Aznar, Vincent Seutin, Henrik H. Hansen, Olivier Waroux, Jens Damsgaard Mikkelsen, Thomas J. Jentsch
Publikováno v: The Journal of Physiology. 586:1823-1832
Neuronal Kv7 channels (also termed KCNQ channels) are the molecular correlate of the M-current. The Kv7 channels activate at rather negative membrane potentials (≤ 60 mV), thereby ‘fine-tuning’ the resting membrane potential. The Kv7 channels a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7b10a3608bd0e9069bb0e0b48e2fdbf9
https://doi.org/10.1113/jphysiol.2007.149450
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6
Exacerbated loss of cell survival, neuropeptide Y-immunoreactive (IR) cells, and serotonin-IR fiber lengths in the dorsal hippocampus of the aged flinders sensitive line 'depressed' rat: Implications for the pathophysiology of depression?
Autor: Susana Aznar, Henriette Husum, Aleksander A. Mathé, A. Møller, Gitta Wörtwein, S. Høyer-Hansen, Jens Damsgaard Mikkelsen, M. Hald Larsen
Publikováno v: Journal of Neuroscience Research. 84:1292-1302
Impairment of hippocampal neurogenesis has been proposed to provide a cellular basis for the development of major depression. Studies have shown that serotonin (5-HT) and neuropeptide Y (NPY) may be involved in stimulating cell proliferation in the d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9a72ca3afc6212a18ea8ab68b5c131b
https://doi.org/10.1002/jnr.21027
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7
Praksispersonalets deltagelse i det kliniske arbejde
Autor: Lars Poulsen, Loni Ledderer, Jens Damsgaard, Lars Foged, Dorte Gilså Hansen, Anders Munck
Publikováno v: Poulsen, L, Ledderer, L, Damsgaard, J, Foged, L, Hansen, D G & Munck, A 2009, ' Praksispersonalets deltagelse i det kliniske arbejde ', Maanedsskrift for Praktisk Laegegerning, bind Årg. 87, nr. 3, s. 329-337 .
Aarhus University
University of Southern Denmark
Udgivelsesdato: Marts
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2d5ed76c98418ab04e7dec6495294971
https://portal.findresearcher.sdu.dk/da/publications/38dc7f60-cdcc-11dd-9908-000ea68e967b
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8
The alpha7 nicotinic receptor agonist SSR180711 increases activity regulated cytoskeleton protein (Arc) gene expression in the prefrontal cortex of the rat
Autor: Søren E. Kristensen, Jens Damsgaard Mikkelsen, Anders Hay-Schmidt, Henrik H. Hansen, Daniel B. Timmermann, Morten S. Thomsen
Publikováno v: Kristensen, S E, Thomsen, M S, Hansen, H H, Timmermann, D B, Hay-Schmidt, A & Mikkelsen, J D 2007, ' The alpha7 nicotinic receptor agonist SSR180711 increases activity regulated cytoskeleton protein (Arc) gene expression in the prefrontal cortex of the rat ', Neuroscience Letters, vol. 418, no. 2, pp. 154-158 . https://doi.org/10.1016/j.neulet.2007.03.016
Nicotinic alpha7 acetylcholine receptors (alpha7 nAChR) have been shown to enhance attentional function and aspects of memory function in experimental models and in man. The protein Arc encoded by the effector immediate early gene arc or arg3.1 has b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::291155e1a7a3e07bf98ac32c4a2d7b44
https://pubmed.ncbi.nlm.nih.gov/17379406
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9
Akademický článek
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10
Unaltered neuropeptide Y (NPY)-stimulated [35S]GTPgammaS binding suggests a net increase in NPY signalling after repeated electroconvulsive seizures in mice
Autor: D.Z. Christensen, David P.D. Woldbye, Jens Damsgaard Mikkelsen, H. Kristiansen, Mikkel V. Olesen
Publikováno v: Journal of neuroscience research. 84(6)
Although electroconvulsive seizures (ECS) are widely used as a treatment for severe depression, the working mechanism of ECS remains unclear. Repeated ECS causes anticonvulsant effects that have been proposed to underlie the therapeutic effect of ECS
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d54bed2d50bcef3c2872d7f1940f2cfa
https://pubmed.ncbi.nlm.nih.gov/16941487
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