Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jens D. Kristensen"'
Autor:
Irwin Klein, Bo Angelin, Anders G. Olsson, Mats Eriksson, Jens D. Kristensen, Paul W. Ladenson, Bo Carlsson, E. Chester Ridgway
Publikováno v:
Journal of Internal Medicine. 277:331-342
Liver-selective thyromimetic agents could provide a new approach for treating dyslipidaemia.We performed a multicentre, randomized, placebo-controlled, double-blind study to evaluate the efficacy and safety of eprotirome, a liver-selective thyroid ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3e86300bd2670bd38385f149ec2f93b
https://doi.org/10.1111/joim.12261
https://doi.org/10.1111/joim.12261
Autor:
Bo Angelin, E. Chester Ridgway, Anders G. Olsson, Jens D. Kristensen, Bo Carlsson, Paul W. Ladenson, John D. Baxter, Irwin Klein
Publikováno v:
New England Journal of Medicine. 362:906-916
Statins effectively reduce levels of serum cholesterol and lower the risk of cardiovascular disease, but have limited effectiveness if stringent goals for serum low-density lipoprotein (LDL) cholesterol levels are not met or adverse effects develop,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef89e659b2c18668a163a823d6f19ae
https://doi.org/10.1056/nejmoa0905633
https://doi.org/10.1056/nejmoa0905633
Publikováno v:
Anesthesia & Analgesia. 82:636-640
The study of spinal cord blood flow (SCBF) after spinal drug application is an important aspect of preclinical neurotoxicological screening. This investigation was designed to study how a new local anesthetic, ropivacaine, affects SCBF after intrathe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dc63c756d4343aebecf1825f1bbf74b
https://doi.org/10.1213/00000539-199603000-00036
https://doi.org/10.1213/00000539-199603000-00036
Autor:
Bengt Långström, Jan Svensson, Johann Valtysson, Jan Persson, Gunnar Antoni, Rolf Karlsten, Per Hartvig, Göran Westerberg, K. J. Lindner, Lars L. Gustafsson, Jens D. Kristensen, Ivar Øye
Publikováno v:
Clinical Pharmacology & Therapeutics. 58:165-173
Plasma concentrations, maximum regional brain concentrations, and specific regional binding in the brain after administration of 0, 0.1, and 0.2 mg/kg doses of (S)-ketamine were measured in a randomized, double-blind, crossover study in five voluntee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::596a89339b0d419c1531eb1a707cafe5
https://doi.org/10.1016/0009-9236(95)90194-9
https://doi.org/10.1016/0009-9236(95)90194-9
Publikováno v:
Anesthesia & Analgesia. 76:1279-1283
Evaluation of spinal cord blood flow (SCBF) is important as a preclinical screening for potential neurotoxicologic side effects before introducing new therapeutic drugs for intrathecal (IT) administration. This study was undertaken to determine wheth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf6029bea35a82a0fe65db453f93710
https://doi.org/10.1213/00000539-199306000-00016
https://doi.org/10.1213/00000539-199306000-00016
Publikováno v:
The Clinical journal of pain. 21(2)
To investigate the effects of gabapentin, carbamazepine, and amitriptyline on temporal summation, simple nociceptive pain, and innocuous touch sensation in healthy volunteers.A placebo controlled four-way crossover double-blind randomized protocol wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44a644345218c9c6266b5296d2bc3e63
https://pubmed.ncbi.nlm.nih.gov/15722805
https://pubmed.ncbi.nlm.nih.gov/15722805
Autor:
Alf Sollevi, Thomas Graven-Nielsen, Lars Arendt-Nielsen, Siegfried Mense, Ylva Jansson, Märta Segerdahl, Jens D. Kristensen
Publikováno v:
Graven-Nielsen, T, Jansson, Y, Segerdahl, M, Kristensen, J D, Mense, S, Arendt-Nielsen, L & Sollevi, A 2003, ' Experimental pain by ischaemic contractions compared with pain by intramuscular infusions of adenosine and hypertonic saline ', European Journal of Pain, vol. 7, no. 1, pp. 93-102 . https://doi.org/10.1016/S1090-3801(02)00069-1
Deep tissue pain can be related to reduced muscle blood flow, which comprises the metabolic demand under muscle work. The tissues and receptors involved in nociception after ischaemic muscle contractions are not known. The concentration of adenosine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfebfaac6f28d1ab554555388e2b929b
https://pubmed.ncbi.nlm.nih.gov/12527322
https://pubmed.ncbi.nlm.nih.gov/12527322
Autor:
Jens D. Kristensen
Publisher Summary This chapter discusses the role of the N -methyl- D -aspartate (NMDA) receptor in pain transmission. The NMDA receptor antagonist (DL-CPP) is a piperazine derivative that acts competitively at the glutamate recognition site. The NMD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f5c577b93c511b5af1c4779b7494fe2
https://doi.org/10.1016/b978-012546820-6/50005-0
https://doi.org/10.1016/b978-012546820-6/50005-0
Publikováno v:
Annals of medicine. 27(2)
Understanding of the complex pharmacology of the spinal cord may lead to rational advances in pain treatment. It appears that a number of specific neurochemical mechanisms exist, by which spinally administered receptor selective agents may modify noc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::619bea26808f76efc9b53b7281300a6d
https://pubmed.ncbi.nlm.nih.gov/7632419
https://pubmed.ncbi.nlm.nih.gov/7632419
Publikováno v:
Pain. 56(1)
This behavioral study was performed in order to delineate the antinociceptive effects of and the influence on motor function of a highly potent, competitive NMDA receptor antagonist 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid (CPP). After int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::099b7b7e4aca23c62c74f13d3c7659c0
https://pubmed.ncbi.nlm.nih.gov/8159442
https://pubmed.ncbi.nlm.nih.gov/8159442