Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Jens Claaßen"'
Autor:
David Pellerin, Felix Heindl, Carlo Wilke, Matt C. Danzi, Andreas Traschütz, Catherine Ashton, Marie-Josée Dicaire, Alexanne Cuillerier, Giulia Del Gobbo, Kym M. Boycott, Jens Claassen, Dan Rujescu, Annette M. Hartmann, Stephan Zuchner, Bernard Brais, Michael Strupp, Matthis Synofzik
Publikováno v:
EBioMedicine, Vol 102, Iss , Pp 105076- (2024)
Summary: Background: GAA-FGF14 disease/spinocerebellar ataxia 27B is a recently described neurodegenerative disease caused by (GAA)≥250 expansions in the fibroblast growth factor 14 (FGF14) gene, but its phenotypic spectrum, pathogenic threshold, a
Externí odkaz:
https://doaj.org/article/6a45cfb1de324e61a33fa2a7a9970a69
Autor:
Dominik Jäschke, Katharina M. Steiner, Dae-In Chang, Jens Claaßen, Ellen Uslar, Andreas Thieme, Marcus Gerwig, Viktor Pfaffenrot, Thomas Hulst, Alexander Gussew, Stefan Maderwald, Sophia L. Göricke, Martina Minnerop, Mark E. Ladd, Jürgen R. Reichenbach, Dagmar Timmann, Andreas Deistung
Publikováno v:
NeuroImage, Vol 270, Iss , Pp 119950- (2023)
Understanding cerebellar alterations due to healthy aging provides a reference point against which pathological findings in late-onset disease, for example spinocerebellar ataxia type 6 (SCA6), can be contrasted. In the present study, we investigated
Externí odkaz:
https://doaj.org/article/07bcb80147d244cb9d7ef51f37d0b8b5
Autor:
Anita Hennig, Jens Claassen, Tatiana Bremova-Ertl, Miriam Kolnikova, Uma Ramaswami, Simon Jones, Jan Raethjen, Kyriakos Martakis, Paul Gissen, Susanne A. Schneider, Anhar Hassan, Tomas Foltan, Reena Sharma, Jordi Gascón-Bayarri, Andreas Hahn
Publikováno v:
Bremova-Ertl, Tatiana; Claassen, Jens; Foltan, Tomas; Gascon-Bayarri, Jordi; Gissen, Paul; Hahn, Andreas; Hassan, Anhar; Hennig, Anita; Jones, Simon A; Kolnikova, Miriam; Martakis, Kyriakos; Raethjen, Jan; Ramaswami, Uma; Sharma, Reena; Schneider, Susanne A (2022). Efficacy and safety of N-acetyl-L-leucine in Niemann-Pick disease type C. Journal of neurology, 269(3), pp. 1651-1662. Springer 10.1007/s00415-021-10717-0
Dipòsit Digital de la UB
Universidad de Barcelona
Journal of Neurology
Dipòsit Digital de la UB
Universidad de Barcelona
Journal of Neurology
Objective To investigate the safety and efficacy of N-acetyl-l-leucine (NALL) on symptoms, functioning, and quality of life in pediatric (≥ 6 years) and adult Niemann–Pick disease type C (NPC) patients. Methods In this multi-national, open-label,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::101d4f5ad5e2702e3c802f701f642125
https://boris.unibe.ch/160811/1/Bremova_Ertl__2021__Efficacy_and_safety.pdf
https://boris.unibe.ch/160811/1/Bremova_Ertl__2021__Efficacy_and_safety.pdf
Autor:
Simon Jones, Jens Claassen, Anita Hennig, Nicolina Goldschagg, Jordi Gascón-Bayarri, Susan Perlman, Andreas Hahn, Tatiana Bremova-Ertl, Susanne A. Schneider, Kyriakos Martakis, Reena Sharma, Anhar Hassan, Heather Lau
Background and ObjectiveGM2 gangliosidosis (Tay-Sachs and Sandhoff diseases) are rare, inherited neurodegenerative disorders with no available symptomatic or disease modifying treatments. This clinical trial aimed to investigate the safety and effica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b9aa38e371f8ad3933e4a8b040e2fd5
https://doi.org/10.1101/2021.09.24.21264020
https://doi.org/10.1101/2021.09.24.21264020
Autor:
Reena Sharma, Jordi Gascón-Bayarri, Miriam Kolnikova, Stephanie Schneider, Jens Claassen, Anita Hennig, Tomas Foltan, Andreas Hahn, Anhar Hassan, T. Bremova-Ertl, Paul Gissen, K. Martakis, Uma Ramaswami, Simon Jones
BackgroundNiemann-Pick disease type C (NPC) is a rare autosomal recessive neurodegenerative disorder characterized by symptoms such as progressive cerebellar ataxia and cognitive decline. The modified amino acid N-acetyl-leucine has been associated w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46fe5fdd4a3b6c2c4c66e63a29e0bc93
https://doi.org/10.1101/2020.12.22.20248704
https://doi.org/10.1101/2020.12.22.20248704
Autor:
Katharina M Steiner, Sophia Göricke, Elke Wondzinski, Dagmar Timmann, Björn Koch, Jens Claassen, Yvonne Gisbertz, Mario Siebler, Dae-In Chang, Thomas M. Ernst, Ellen Uslar
Publikováno v:
The Cerebellum. 18:166-177
Extinction of conditioned aversive responses (CR) has been shown to be context-dependent. The hippocampus and prefrontal cortex are of particular importance. The cerebellum may contribute to context-related processes because of its known connections
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b42ac52e9ef058c5c0058a4dab5fd362
https://doi.org/10.1007/s12311-018-0973-y
https://doi.org/10.1007/s12311-018-0973-y
Autor:
Dagmar Timmann, Nina Theysohn, Ulrike Bingel, Sigrid Elsenbruch, Michael Forsting, Jens Claassen, Franziska Labrenz, Thomas M. Ernst, Laura Ricarda Koenen
Publikováno v:
Journal of neurology, neurosurgery, and psychiatry. 91(2)
Chronic pain disorders are extremely common, including chronic back pain and headaches, but also chronic visceral pain disorders, such as irritable bowel syndrome. Treatment is notoriously difficult. A detailed understanding of the neural pain circui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb7d16fdbe6aaf6713414d9d4e7021c
https://pubmed.ncbi.nlm.nih.gov/31558651
https://pubmed.ncbi.nlm.nih.gov/31558651
Publikováno v:
Journal of Neurophysiology, 121(6), 2112-2125. American Physiological Society
Previous studies have shown that cerebellar transcranial direct current stimulation (tDCS) leads to faster adaptation of arm reaching movements to visuomotor rotation and force field perturbations in healthy subjects. The first aim of the present stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06670b85c56ef2dcebf2bb07d13b93ee
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85067905977
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85067905977
Autor:
Parvis Farahmand, Klaus Jahn, Ales Hahn, Julian Teufel, Rainer Spiegel, Jens Claassen, Fábio Anciães da Silva, Stanislav Bardins, N. Rettinger, Roger Kalla, Michael Strupp, Thomas Brandt, Erich Schneider
Publikováno v:
Annals of the New York Academy of Sciences. 1375:66-73
Resting in an upright position during daytime decreases downbeat nystagmus (DBN). When measured in brightness only, that is, without intermitting exposure to darkness, it does not make a significant difference whether patients have previously rested
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f86b15627271d6cca7ca81595d2cdddf
https://doi.org/10.1111/nyas.13172
https://doi.org/10.1111/nyas.13172
Autor:
Michael Strupp, Roger Kalla, Roman Schniepp, Julian Teufel, Jens Claaßen, Stanislavs Bardins, Klaus Jahn, Siegbert Krafczyk, Katharina Feil, Erich Schneider
Publikováno v:
Feil, Katharina; Claassen, Jens; Bardins, Stanislavs; Teufel, Julian; Krafczyk, Siegbert; Schneider, Erich; Schniepp, Roman; Jahn, Klaus; Kalla, Roger; Strupp, Michael (2013). Effect of chlorzoxazone in patients with downbeat nystagmus: A pilot trial. Neurology, 81(13), pp. 1152-1158. Lippincott Williams & Wilkins 10.1212/WNL.0b013e3182a55f6d
Objective: Downbeat nystagmus (DBN) is the most frequent form of acquired persisting fixation nystagmus with different symptoms such as unsteadiness of gait, postural instability, and blurred vision with reduced visual acuity (VA) and oscillopsia. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5288aca7e4ff9daaa4b971c619e4d53d
https://doi.org/10.1212/wnl.0b013e3182a55f6d
https://doi.org/10.1212/wnl.0b013e3182a55f6d