Cryoneurolysis versus radiofrequency ablation outcome on pain experience in chronic low back pain (COPE): a single-blinded randomised controlled trial

Autor: Maurits van Tulder, Lone Nikolajsen, Jens Christian Hedemann Sørensen, Kaare Meier, Kamilla Truong, Lasse Cramer Ahrens, Thea Overgaard Wichmann, Hamed Zaer, Lasse Hubertus Tiroke, Simon Arvin, Mindaugas Bazys, Peter Duel, Gudrun Gudmundsdottir, Jakob Gram Carlsen, Mikkel Mylius Rasmussen

Publikováno v: RMD Open, Vol 10, Iss 2 (2024)

Objective A comparison of cryoneurolysis or radio frequency (RF) with placebo in patients with facetogenic chronic low back pain (LBP) for patient global impression of change (PGIC), pain intensity, function and quality of life, with 1-year follow-up

Externí odkaz: https://doaj.org/article/def0c241646646d5aeec4e0d0170d92e

Spinal cord stimulation therapy for patients with Parkinson’s disease and gait problems (STEP-PD): study protocol for an exploratory, double-blind, randomised, placebo-controlled feasibility trial

Autor: Nicola Pavese, Jens Christian Hedemann Sørensen, Elena Moro, Andreas Nørgaard Glud, Victor S Hvingelby, Miriam Højholt Terkelsen, Erik L Johnsen, Mette Møller, Erik Hvid Danielsen, Tove Henriksen, Yen Tai, Anne Sofie Møller Andersen, Kaare Meier, Per Borghammer

Publikováno v: BMJ Neurology Open, Vol 4, Iss 2 (2022)

Introduction Gait difficulties are common in Parkinson’s disease (PD) and cause significant disability. These symptoms are often resistant to treatment. Spinal cord stimulation (SCS) has been found to improve gait, including freezing of gait, in a

Externí odkaz: https://doaj.org/article/d5cfe35b2e994bab9b8c3404132ffbdd

Activation of NMDA receptor ion channels by deep brain stimulation in the pig visualised with [18F]GE-179 PET

Autor: Ali Khalidan Vibholm, Anne Marlene Landau, Aage Kristian Olsen Alstrup, Jan Jacobsen, Kim Vang, Ole Lajord Munk, Martin Jensen Dietz, Dariusz Orlowski, Jens Christian Hedemann Sørensen, David James Brooks

Publikováno v: Brain Stimulation, Vol 13, Iss 4, Pp 1071-1078 (2020)

Background: No PET radioligand has yet demonstrated the capacity to map glutamate N-methyl-d-aspartate receptor ion channel (NMDAR-IC) function. [18F]GE-179 binds to the phencyclidine (PCP) site in open NMDAR-ICs and potentially provides a use-depend

Externí odkaz: https://doaj.org/article/c22c056fe5cc4cf1a1fa1cf055b0ecaf

Dopaminergic Neuromodulation of Spike Timing Dependent Plasticity in Mature Adult Rodent and Human Cortical Neurons

Autor: Emma Louise Louth, Rasmus Langelund Jørgensen, Anders Rosendal Korshoej, Jens Christian Hedemann Sørensen, Marco Capogna

Publikováno v: Frontiers in Cellular Neuroscience, Vol 15 (2021)

Synapses in the cerebral cortex constantly change and this dynamic property regulated by the action of neuromodulators such as dopamine (DA), is essential for reward learning and memory. DA modulates spike-timing-dependent plasticity (STDP), a cellul

Externí odkaz: https://doaj.org/article/200e8608f0374af2b970e2f3cfbe9275

Burst Spinal Cord Stimulation in Pregnancy: First Clinical Experiences

Autor: Kaare Meier, Julie Glavind, Ioanna Milidou, Jens Christian Hedemann Sørensen, Puk Sandager

Publikováno v: Meier, K, Glavind, J, Milidou, I, Sørensen, J C H & Sandager, P 2023, ' Burst Spinal Cord Stimulation in Pregnancy : First Clinical Experiences ', Neuromodulation: Technology at the Neural Interface, vol. 26, no. 1, pp. 224-232 . https://doi.org/10.1016/j.neurom.2022.03.008

OBJECTIVES: Spinal cord stimulation (SCS) is a treatment for chronic neuropathic pain. It is based on the delivery of electric impulses to the spinal cord, traditionally in a regular square-wave pattern ("tonic" stimulation) and, more recently, in a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172f18220420805b1d6dd0f327e86e52
https://doi.org/10.1016/j.neurom.2022.03.008