Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Jens Chr. Jensenius"'
Autor:
Jens Chr. Jensenius, Bent Deleuran, Anne Troldborg, Kristian Stengaard-Pedersen, Steffen Thiel, Søren Hansen, Magdalena Janina Laska, Lone Donbæk Jensen
Publikováno v:
Troldborg, A, Thiel, S, Jensen, L, Hansen, S W K, Laska, M J, Deleuran, B, Jensenius, J C & Stengaard-Pedersen, K 2015, ' Collectin liver 1 and collectin kidney 1 and other complement-associated pattern recognition molecules in systemic lupus erythematosus ', Clinical and Experimental Immunology, vol. 182, no. 2, pp. 132-138 . https://doi.org/10.1111/cei.12678
Summary The objective of this study was to explore the involvement of collectin liver 1 (CL-L1) and collectin kidney 1 (CL-K1) and other pattern recognition molecules (PRMs) of the lectin pathway of the complement system in a cross-sectional cohort o
Autor:
Christel R. Brinkmann, Mogens Larsen, Steffen Thiel, Christian W. Heegaard, Jens Chr. Jensenius, Thor Petersen
Publikováno v:
Brinkmann, C R, Thiel, S, Larsen, M K, Petersen, T E, Jensenius, J C & Heegaard, C W 2011, ' Preparation and comparison of cytotoxic complexes formed between oleic acid and either bovine or human α-lactalbumin ', Indian Journal of Dairy Science, vol. 94, no. 5, pp. 2159-2170 . https://doi.org/10.3168/jds.2010-3622
α-Lactalbumin is a ubiquitous calcium-binding milk protein with a well-characterized function in regulating the synthesis of lactose. An entirely different activity has been shown to occur when a complex is formed between calcium-free α-lactalbumin
Autor:
Roland A. Ammann, Andreas Hirt, Luregn J. Schlapbach, Christoph Aebi, Jens Chr. Jensenius, Annette G. Hansen
Publikováno v:
Schlapbach, L J, Aebi, C, Hansen, A, Hirt, A, Jensenius, J C & Ammann, R A 2009, ' H-ficolin serum concentration and susceptibility to fever and neutropenia in paediatric cancer patients ', Clinical and Experimental Immunology, vol. 157, no. 1, pp. 83-9 . https://doi.org/10.1111/j.1365-2249.2009.03957.x
Summary H-ficolin (Hakata antigen, ficolin-3) activates the lectin pathway of complement similar to mannose-binding lectin. However, its impact on susceptibility to infection is currently unknown. This study investigated whether the serum concentrati
Autor:
Michael R. Hamblin, Steffen Thiel, Mette Møller-Kristensen, Jens Chr. Jensenius, Kazue Takahashi
Publikováno v:
Møller-Kristensen, M, Hamblin, MR, Thiel, S, Jensenius, J C & Takahashi, K 2007, ' Burn injury reveals altered phenotype in mannan-binding lectin-deficient mice ', J. Invest. Dermatol., vol. 127, pp. 1524-31 .
Møller-Kristensen, M, Hamblin, M R, Thiel, S, Jensenius, J C & Takahashi, K 2007, ' Burn injury reveals altered phenotype in mannan-binding lectin-deficient mice ', Journal of Investigative Dermatology, vol. 127, no. 6, pp. 1524-31 . https://doi.org/10.1038/sj.jid.5700748
Møller-Kristensen, M, Hamblin, M R, Thiel, S, Jensenius, J C & Takahashi, K 2007, ' Burn injury reveals altered phenotype in mannan-binding lectin-deficient mice ', Journal of Investigative Dermatology, vol. 127, no. 6, pp. 1524-31 . https://doi.org/10.1038/sj.jid.5700748
Burn injury destroys skin, the second largest innate immune organ in the body, and triggers chaotic immune and inflammatory responses. The pattern recognition molecule, mannan-binding lectin (MBL), plays an important role in the first-line host defen
Autor:
Finn Matthiesen, Lisbeth Jensen, Jens Chr. Jensenius, Steffen Thiel, Pernille Dorthea Frederiksen, Annette G. Hansen
Publikováno v:
Frederiksen, P D, Thiel, S, Jensen, L, Hansen, A G, Matthiesen, F & Jensenius, J C 2006, ' Quantification of mannan-binding lectin ', Journal of Immunological Methods, vol. 315, no. 1-2, pp. 49-60 . https://doi.org/10.1016/j.jim.2006.07.001
Mannan-binding lectin (MBL) is attracting considerable interest due to its role in the immune defense. The high frequency of congenital MBL deficiency makes it feasible to evaluate clinical relevance through epidemiological investigations on fairly l
Autor:
Jens Chr Jensenius, Ivan Dobrev, Marieta M. Rouseva, Uday Kishore, Mihaela Gadjeva, Rohit Ghai, Martin Kolev, A. Zlatarova, Neli Olova, Mihaela S. Kojouharova, Kenneth B.M. Reid, Lubka T. Roumenina
Publikováno v:
Zlatarova, A S, Rouseva, M, Roumenina, L T, Gadjeva, M, Kolev, M, Dobrev, I, Olova, N, Ghai, R, Jensenius, J C, Reid, K B M, Kishore, U & Kojouharova, M S 2006, ' Existence of different but overlapping IgG-and IgM-binding sites on the globular domain of human C1q ' Biochemistry, vol. 45, no. 33, pp. 9979-88 . https://doi.org/10.1021/bi060539v
C1q is the first subcomponent of the classical complement pathway that binds antigen-bound IgG or IgM and initiates complement activation via association of serine proteases C1r and C1s. The globular domain of C1q (gC1q), which is the ligand-recognit
Autor:
I. J. Christensen, L. Basse, Jacob Alexander Lykke, Steffen Thiel, Hans Jørgen Nielsen, Jens Chr. Jensenius, Henriette Ytting
Publikováno v:
Ytting, H, Christensen, I J, Basse, L, Lykke, J, Thiel, S, Jensenius, J C & Nielsen, H J 2006, ' Influence of major surgery on the mannan-binding lectin pathway of innate immunity ', Clin. Exp. Immunol., vol. 144, pp. 239-46 .
Ytting, H, Christensen, I J, Basse, L, Lykke, J, Thiel, S, Jensenius, J C & Nielsen, H J 2006, ' Influence of major surgery on the mannan-binding lectin pathway of innate immunity ', Clinical and Experimental Immunology, vol. 144, no. 2, pp. 239-46 . https://doi.org/10.1111/j.1365-2249.2006.03068.x
Ytting, H, Christensen, I J, Basse, L, Lykke, J, Thiel, S, Jensenius, J C & Nielsen, H J 2006, ' Influence of major surgery on the mannan-binding lectin pathway of innate immunity ', Clinical and Experimental Immunology, vol. 144, no. 2, pp. 239-46 . https://doi.org/10.1111/j.1365-2249.2006.03068.x
Summary The mannan-binding lectin (MBL) pathway of complement activation is important in host defence against pathogens and possibly against cancer. We investigated the effect of major surgery on two central components of the MBL pathway; MBL and the
Publikováno v:
Molecular Immunology
Aarhus University
Thiel, S, Frederiksen, P D & Jensenius, J C 2005, ' Clinical manifestations of mannan-binding lectin deficiency ', Mol. Immunol, vol. 43, pp. 86-96 .
Thiel, S, Frederiksen, P D & Jensenius, J C 2006, ' Clinical manifestations of mannan-binding lectin deficiency ', Mol. Immunol, vol. 43, pp. 86-96 .
Thiel, S, Frederiksen, P D & Jensenius, J C 2006, ' Clinical manifestations of mannan-binding lectin deficiency ', Molecular Immunology, vol. 43, no. 1-2, pp. 86-96 . https://doi.org/10.1016/j.molimm.2005.06.018
Aarhus University
Thiel, S, Frederiksen, P D & Jensenius, J C 2005, ' Clinical manifestations of mannan-binding lectin deficiency ', Mol. Immunol, vol. 43, pp. 86-96 .
Thiel, S, Frederiksen, P D & Jensenius, J C 2006, ' Clinical manifestations of mannan-binding lectin deficiency ', Mol. Immunol, vol. 43, pp. 86-96 .
Thiel, S, Frederiksen, P D & Jensenius, J C 2006, ' Clinical manifestations of mannan-binding lectin deficiency ', Molecular Immunology, vol. 43, no. 1-2, pp. 86-96 . https://doi.org/10.1016/j.molimm.2005.06.018
Mannan-binding lectin (MBL) is a plasma protein of the innate immune system with the ability to initiate antimicrobial and inflammatory actions. MBL deficiency is common. More than 10% of the general population may, depending on definition, be classi
Autor:
Steffen Thiel, Lennart Truedsson, Peter Meyer, Lena Mared, Leif Eriksson, Ragnhild Kornfält, Michael C. Carlsson, Birgitta Gullstrand, Mihaela Gadjeva, Anders G. Sjöholm, Jens Chr. Jensenius
Publikováno v:
Molecular Immunology. 40:171-228
Autor:
Liselotte E. Jensen, Steen V. Petersen, Frederik Dagnaes Hansen, Jens Chr. Jensenius, Søren Hansen, Alan Ezekowitz, Steffen Thiel, Hong Liu, Kazue Takahashi
Publikováno v:
Scandinavian Journal of Immunology. 53:489-497
Rat monoclonal antibodies (MoAbs) against mouse mannan-binding lectin (MBL)-A and MBL-C were generated and assays for MBL-A and MBL-C were constructed. This allowed for the quantitative analysis of both proteins for the first time. Previously only MB